Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

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      97 007
      Study of a new version of classical Thin-Layer Chromatography with a closed adsorbent layer
      V. G. BEREZKIN*, E. V. KORMISHKINA (*A. V. Topchiev Institute of Petro-Chemical Synthesis, Russian Academy of Sciences, Leninski Prospekt 29, Moscow 119991, Russia)

      J. Planar Chromatogr. 19, 81-85 (2006). A simple device is proposed for chromatographic separation with a traditional plate under the condition of a closed adsorbent layer (TLC-CL). Compared with traditional TLC the new variant has certain advantages, it takes for example 20-30 % less time; the efficiency of TLC-CL was, however, usually less than that of traditional TLC.

      Classification: 3c
      97 137
      Determination of rutin in Ginkgo Biloba from a solid dosage form by High Performance Thin Layer Chromatography
      S.Y.GANDHE, S.V.PIMPLE* AND M.A. JOSHI (*Emcure R & D Centre, T-184 MIDC Bhosari, Pune 411026, India)

      Indian Drugs 42 (9), 592-596 (2005). HPTLC of rutin in Ginkgo biloba from a solid dosage form, on silica gel with n-butanol - n-propanol - chloroform - acetic acid-water 4:1:2:1:1 containing 1 % formic acid. Quantitative determination by absorbance measurement at 254 nm. Rf value of rutin was 0.24. The method was linear in the range of 30-70 ng/µL. No interference was observed from excipients present in solid dosage form.

      Classification: 32a
      98 106
      On problems with liquid chromatographic quantification of chiral 2-arylpropionic acids by use of UV-absorbtion-based detection
      M. SAJEWICZ*, T. KOWALSKA (*Inst. of Chem., Silesian Univ., 9 Szkolna Street, 40-006 Katowice, Poland)

      Acta Chrom. 17, 292-301 (2006). TLC of ibuprofen and naproxen on silica gel pre-washed with methanol - water 9:1 and dryed at ambient temperature for 3 h. The plates were impregnated with a 0.03 M solution of L-arginine in methanol. Development with acetonitrile - methanol - water 5:1:1 containing several drops of glacial acetic acid for S-(+)-ibuprofen, and acetonitrile - methanol - water 10:2:3 containing several drops of glacial acetic acid for S-(+)-naproxen. Densitometry at 200, 205, and 210 nm for S-(+)-ibuprofen and at 202, 215, and 225 nm for S-(+)-naproxen. The investigations were performed by using three independent measurement techniques, all based on UV absorption: HPLC–UV, HPLC–DAD, and TLC–densitometry.

      Classification: 32a
      100 146
      Development & Validation of HPTLC method for Estimation of Metformin HCl
      M. REDDY*, G. MUBEEN, Sanjay PAI, P.N. GORLE, L. GANESH, B.K. GOPAL (*R.R. College of Pharmacy, Chikkababavara, Bangalore, Karnataka, India)

      59th Indian Pharmaceutical Congress F-55, 402, (2007). HPTLC of metformin hydrochloride on silica gel with methanol - chloroform - ammonium acetate 6:3:1. Densitometry at 236 nm. The method has a range from 100 - 300 ng/zone. The limit of detection and quantification was 25 ng and 100 ng/zone, respectively. The method was applied for analysis of metformin hydrochloride in multi-component formulations containing glipizide, gliclazide and glibenclamide as well as in serum.

      Classification: 32a
      101 097
      Use of different salt solutions in salting-out TLC of Co(III) complexes on silica gel
      Vukosava ŽIVKOVIC-RADOVANOVIC*, Gordana VUCKOVIC (*Faculty of Chemistry, University of Belgrade, P.O. Box 158, 11001 Belgrade, Serbia)

      Chromatographia 67 (3-4), 259-267 (2008). Investigation of saturated aqueous solutions of 28 different salts used as potential mobile phases for salting-out TLC, on silica gel, of a series of four mixed bis-aminocarboxylato cobalt(III) complexes. Confirmation of three alkali metal chlorides, and four alkaline earth metal chlorides, for linear dependences previously established on different adsorbents with (NH4)2SO4 solutions by linear regression analysis of chromatographic data obtained for fifteen mixed aminocarboxylato Co(III) complexes (four series) with solutions of ammonium chloride. Comparison of separation achieved with different salts. Li+, Mg2+, and Ca2+ chlorides are most suitable.

      Classification: 33a
      103 031
      Pressurized planar electrochromatography as the mode for determination of solvent composition - retention relationships in reversed-phase systems
      T.H. DZIDO*, P.W. PLOCHARZ, A. KLIMEK-TUREK, A. TORBICZ, B. BUSZEWSKI (*Department of Physical Chemistry, Medical University, Lublin, Poland; tadeusz.dzido@am.lublin.pl)

      J. Planar Chromatogr. 21, 295-298 (2008). HPTLC of a test compound [1-(4-hydroxyphenylazo)-2-napthol] on RP-18 (prewashed with methanol) with acetonitrile - water - buffer (pH 4.8) in the desired volume ratio in a horizontal developing chamber saturated for 15 min. Quantitative determination by absorbance measurement with a diode array TLC scanner. The retention-composition relationship obtained with TLC is similar to those of pressurized planar electrochromatography and HPLC in the modifier concentration range 60-80 % but deviates substantially at higher modifier concentrations.

      Classification: 7
      104 234
      Iridoid glycoside-based quantitative chromatographic fingerprint analysis
      A. YADAV*, N. TIWARI, P. SRIVASTAVA, S. SINGH, K. SHANKER, R. VERMA, M. GUPTA (*Analytical Chemistry Div. Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, India, guptammg@rediffmail.com)

      J. Pharm. Biomed. Anal. 47, 841-846 (2008). HPTLC of iridoid glycosides in the aerial part of Gambhari (Gmelina arborea) with iridoid gycoside 6-0-(2”, 3”- dibenzoyl)-o-L-rhamnopyranosylcatalpol as a chemical marker for the standardization of G. arborea plant extracts on silica gel with chloroform - methanol 4:1. Quantitative determination by absorbance measurement at 240 nm and at 430 nm after derivatization with vanillin - sulfuric acid reagent. The linear working range was between 1000-5000 ng/spot with a good correlation coefficient of 0.994.

      Classification: 32e
      105 080
      Development of validated HPTLC & HPLC methods for estimation of citicoline sodium in tablet dosage form
      V. KUMAR*, S. VARGHESE, H. JOHN (*Dept. of Pharmaceutical Analysis, College of Pharmacy, SRIPMS, Coimbatore, T.N., India)

      IPA Convention, 2010, RA-PO 35. HPTLC of citicoline sodium in tablet formulation on silica gel with chloroform - methanol - water 3:7:3. The compound was well resolved with an hRf value of 53. Densitometric measurement at 280 nm. The method was linear in the range of 300-900 ng/band. HPLC analysis was performed on RP18 column using 1 % formic acid - methanol 19:1. Results obtained with either method were comparable.

      Classification: 32a