Cumulative CAMAG Bibliography Service CCBS
Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.
The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:
- Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
- Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
- Keyword register: select an initial character and browse associated keywords
- Search by CBS edition: Select a CBS edition and find all related publications
Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.
Biomed. Chromatogr. 10, 146-147 (1996). TLC on silica by developing twice with 1) ethyl acetate - isooctane - acetic acid 100:400:11, and 2) ethyl acetate - hexane 3:1. Detection by spraying with Triton X-100 - chloroform - petrol ether 1:9:30. Quantification by densitometry at 340 nm/> 540nm.
J. Pharm. Biomed. Anal. 39, 581-586 (2005). For post-production quality control of camptothecin derivatives irinotecan (CPT 11) and topotecan (TPT), HPLC and HPTLC methods have been developed which were suitable for identification, determination of purity and quantification. HPTLC on silica gel with methylene chloride - methanol - formic acid - water 82:24:2:1. After development, the plate was soaked in 15 % paraffin in n-heptane. Quantitative determination by fluorescence measurement at 366/>400 nm. The method was linear within the range of 100-1000 ng/mL for both CPT-11 and TPT. The method was validated for accuracy, precision, LOD, and LOQ.
J. Planar Chromatogr. 21, 209-212 (2008). HPTLC of levofloxacon, (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, and amlodipine besylate (as internal standard) on silica gel, prewashed with methanol, with chloroform - methanol - acetic acid 58:39:3 in a twin trough chamber. Quantitation by densitometry at 300 nm (levofloxacin) and 350 nm (internal standard).
J. Chromatogr. B 877 (29), 3719-3723 (2009). HPTLC of gemifloxacin mesylate in human plasma, extracted with chloroform - acetic acid 59:1, on silica gel with ethyl acetate – methanol - ammonia 8:4:3. The hRf value of gemifloxacin mesylate was 33. Quantification by densitometry at 254 nm. The calibration curve was established in the range of 50 to 600 ng/spot. Recovery of gemifloxacin mesylate was between 80.0 and 86.2 %. The stability of gemifloxacin mesylate in plasma was confirmed with samples submitted to three cycles of freeze–thawing at -20 °C, and with samples stored on the bench for 12 h.
J. Planar Chromatogr. 24, 222-226 (2011). HPTLC of lamotrigine in human serum with chloramphenicol as internal standard on silica gel, prewashed with methanol, with ethyl acetate - methanol - 32 % aqueous ammonia 17:2:1 in a saturated twin-trough chamber. Quantitative determination by densitometry at 280 nm. The hRf of lamotrigine was 37. Linearity was between 0.6 and 300 ng/band, corresponding to 0.06-30.00 ng/µL lamotrigine in human serum after extraction and application of 1 µL to the chromatographic plate. The correlation coefficient was 0.998. Intra-assay and inter-assay precision (%RSD) were in the range of 0.5-2.9 % (n = 3) and 1.6 -2.9 % (n = 9), respectively. LOD and LOQ were 16 and 42 pg/zone, respectively. Recovery (by standard addition) was between 94.1-101.3 %, with %RSD not higher than 3.5 %.
J. Planar Chromatogr. 27, 377-384 (2014). HPTLC of metformin in urine on silica gel with chloroform – methanol – ammonia 27 % 25:25:1. Quantitative determination by absorbance measurement at 237 nm. The hRF value of metformin was 25. Linearity was between 200 and 2000 ng/zone. The intermediate inter-day and intra-day precisions were below 9 % (n=5). The LOD and LOQ were 40 and 120 ng/zone, respectively. Recoveries were in the range of 92-94 %.
J. Chromatogr. Sci. 56, 498-509 (2018). Investigation of the analysis of valsartan (VAL) and sacubitril (SAC) in their supramolecular complex (LCZ696), a newly approved remedy for heart failure, along with the SAC-related substance biphenyl methyl pyrrolidinone (BMP). BMP is an intermediate of the SAC synthesis and is a suspected impurity for SAC and/or LCZ696 tablets. HPTLC coupled with a fluorescence detector (FLD) and a diode array detector (DAD) aimed at analyzing BMP at the low level of 3 % in the presence of its parent drug, SAC. HPLC-FLD and HPLC-DAD were used for detection and quantitation of lower BMP concentrations.
Clin. Chim. Acta 147, 183-90 (1985). TLC of sphingomyelin, phosphatidylcholine, phosphatidylserine and phosphatidylethanolamine on silica with chloroform - methanol - acetic acid - water 100:55:16:6. Detection by staining with Naphtho Blue Black. Quantification by spectrodensitometry.