Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      78 121
      Quantitative analysis of lamotrigine in plasma and tablets by planar chromatography and UV spectrophotometry
      E. DREASSI*, G. CORBINI, P. CORTI, M. ULIVELLI, R. ROCCHI, (Univ. of Siena, Dept. of Chem. and Pharm. Techn., Via Banchi di Sotto 55, 53100 Siena, Italy)

      J. AOAC Int. 79, 1277-1280 (1996). TLC of lamotrigine (3,5-diamino-6-[2,3-dichlorophenyl]-1,2,4-triazine), 3,5-diamino-6-[2-methoxyphenyl]-1,2,4-triazine (as internal standard), carbamazepine and carbamazepine-10,11-epoxide, phenytoine, phenobarbitone, clonazepam, clobazam, on silica with ether - methanol - acetic acid 80:19:1 protected from light. Quantification by densitometry at 306 nm. Detection limit of lamotrigine 0.27 mg/ml.

      Classification: 32a, 32f
      96 118
      HPTLC method for quantitative estimation of corticosterone in rat plasma
      S. MARIHAL*, V. MARDANE, C. PATIL (*Department of Pharmaceutical Analysis, Goa College of Pharmacy, 18th June Road, Panaji 408001, Goa, India)

      Abstract G-19, IPC (2005). HPTLC for estimation of corticosterone in rat plasma on silica gel with chloroform - methanol - water 9:10:1. Quantitative determination by absorbance measurement at 245 nm. Betamethasone was employed as internal standard. The extraction of plasma with ethyl acetate gave an average recovery of >85 %. The linearity was within the range of 30-300 ng/mL with LOQ being 30 ng. The method was found to be rugged and robust.

      Classification: 13, 32a
      102 017
      Analysis of brain lipids by direct coupled matrix-assisted laser desorption ionization time-of-flight mass spectrometry and high-performance thin-layer chromatography
      B. FUCHS, A. NIMPTSCH, R. SÜSZ, J. SCHILLER* (*University of Leipzig, Institute of Medical Physics and Biophysics, Faculty of Medicine, Härtelstr. 16-18, 04107 Leipzig, Germany; juergen.schiller@medizin.uni-leipzig.de)

      J. AOAC Int. 91, 1227-1236 (2008). HPTLC on silica gel using chloroform - ethanol - water - triethylamine 5:5:1:5 for separation of phospholipids and chloroform - acetone - methanol - acetic acid - water 46:17:15:14:8 and chloroform - methanol - acetic acid 13:5:2 for separation of glycolipids. Visualization by spraying with primuline reagent (Direct Yellow) and observation under UV light at 366 nm. Also MALDI-TOF-MS analysis.

      Classification: 11c
      105 059
      Bioassay guided fractionation of Lagenaria siceraria for antihyperlipidemic activity
      M. BOMBAYWALA*, D. MOHALE, A. CHANDEWAR (*P. WADHWANI College of Pharmacy, Yavatmal, Mah, India)

      International Seminar on Herbal Drug Research, PN-009 (2009). Bioassay guided fractionation of Lagenaria siceraria was carried out on a silica gel column with solvents in ascending order of polarity. Each fraction obtained was subjected to preparative TLC on silica gel with n-butanol - methanol - water 3:1:1. Four bands with different Rf values were collected and active compounds were extracted and screened for antihyperlipidemic activity.

      Classification: 32e
      109 061
      A simple, rapid, and sensitive HPTLC method for the estimation of clarithromycin
      P. LOYA, P. D. HAMRAPURKAR* (*Principal K. M. Kundnani College of Pharmacy, Plot no. 23, Joy Building, Rambhau, Salgaonkar Marg, Cuffe parade, Colaba, Mumbai - 400 005, India; phamrapurkar@gmail.com)

      J. Planar Chromatogr. 24, 534-538 (2011). HPTLC of clarithromycin in plasma on silica gel (prewashed with methanol) with ethyl acetate - methanol - 15 % ammonium acetate (pH 10.6) 7:2:1 in a twin-trough chamber with saturation for 15 min. Detection by dipping into xanthydrol solution (10 % in methanol). Quantitative determination by densitometry in absorbance mode at 506 nm. The hRf was 62. The method was linear over the range of 0.1-3.0 µg/mL (r2 = 0.9974). The recovery (by standard addition) was over 85 %. The intra-day and inter-day precision (%RSD) of the assay was in the range of 0.8-4.6 %. The recovery was above 95 %.

      Classification: 28a
      114 084
      Development of validated HPTLC method for quantification of trazodone in human serum
      Sigrid MENNICKENT*, Ana GONZALEZ, M. VEGA, Gisela RIOS, Marta DE DIEGO (*Department of Pharmacy, Faculty of Pharmacy, University of Concepción, P.O.Box 237, Concepción, Chile, smennick@udec.cl)

      J. Chil. Chem. Soc. 59, 2405-2408 (2014). HPTLC of trazodone in human serum on silica gel with toluene - acetone - ethanol - ammonium 18:14:4:1. Quantitative determination by absorbance measurement at 290 nm. The hRF values of trazodone and its metabolite were 82 and 39, respectively. Linearity was between 0.2 and 2 ng/zone. The intermediate intra-day and inter-day precisions were below 3.5 % (n=3). The LOD and LOQ were 16 and 48 pg/zone, respectively. Recoveries for trazodone were in the range of 94.7-99.0 %.

      Classification: 32c, 32f
      122 025
      High-performance thin-layer chromatography coupled with electrospray ionization tandem mass spectrometry for identifying neutral lipids and sphingolipids in complex samples
      Carmen JARNE*, M. SAVIRON, M. LAPIEZA, L. MEMBRADO, J. ORDUNA, J. GALBAN, R. GARRIGA, G. MORLOCK, V. CEBOLLA (*Instituto de Carboquímica, ICB-CSIC, C/ Miguel Luesma, 4, 50018 Zaragoza, Spain, vcebolla@icb.csic.es)

      J. AOAC Int. 101, 1993-2000 (2018). HPTLC of neutral lipids in fatty acid methyl ester (FAME)-derived biodiesel (1) and sphingolipids in human plasma (2) on LiChrospher or silica gel with a 4-step gradient based on t-butyl methyl ether, dichloromethane, and n-heptane for (1) and a 7-step gradient based on methanol and dichloromethane for (2). Detection of neutral lipids by dipping into a methanolic primuline solution (0.02 g/100 mL), followed by fluorescence recording at 366/>400 nm. Detection of sphingolipids by absorbance measurement at 190 nm. Zones of interest were eluted into an electrospray ionization-ion trap MS (ESI-MS) using a TLC-MS interface. _x000D_

      Classification: 4e, 11c, 11e
      57 084
      Dtsch
      H. WAGNER, H. REGER, R. BAUER

      Apoth. Ztg. 125, 1513-1517 (1985). Saponinhaltige Drogen und Fertigarzneimittel. HPLC-Analyse am Beispiel von Rosskastaniensamen. (Qualitative and quantitative analysis of the saponins of hippocastani semen and pharmaceutical preparations using reversed-phase HPLC.) TLC of chestnut extracts on silica with chloroform - methanol - acetic acid - water 60:32:12:8. Identification of beta-escin and cryptoescin.

      Classification: 14