Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

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      124 014
      Quantification of bioactive lignans in sesame seeds using HPTLC densitometry: Comparative evaluation by HPLC-PDA
      E. MIKROPOULOU, E. PETRAKIS, A. ARGYROPOULOU, S. MITAKOU, Maria HALABALAKI*, L. SKALTSOUNIS (*Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece, mariahal@pharm.uoa.gr)

      Food Chem. 288, 1-7 (2019). HPTLC of sesamin (1) and sesamolin (2) in sesame seed extracts on silica gel with n-pentane - diethyl ether 3:2. Quantitative determination by absorbance measurement at 290 nm. Linearity was between 25 and 150 µg/mL for (1) and 12.5 and 75 µg/mL for (2). Intermediate precision was below 3 % (n=6). The LOD and LOQ were 1.3 and 4 µg/mL for (1) and 0.4 and 1 µg/mL for (2), respectively. Recovery rate was  between 95 and 105 % for (1) and (2). Correlation of the HPTLC and a HPLC-PDA method was notably high. 

      Classification: 7
      124 058
      Development and validation of a high-performance thin-layer chromatographic method for the simultaneous estimation of torsemide and eplerenone by quality by design approach
      S. V. TATHE*, P.R. DESHMUKH, A.M. KASHID, S. GALKWAD (*Department of Pharmaceutical Chemistry, Sinhgad Institute of Pharmacy, Narhe, Pune 41, Maharashtra, India, tatheshraddha09@gmail.com)

      J. Planar Chromatogr. 32, 411-420 (2019). HPTLC of torsemide (1) and eplerenone (2) on silica gel aluminum foil with toluene - ethyl acetate - glacial acetic acid 70:30:1. Quantitative determination by absorbance measurement at 297 nm. The hRF values for (1) and (2) were 24 and 50, respectively. Linearity was between 50 and 300 ng/zone for (1) and 125 and 1225 ng/zone for (2). Intermediate precision was below 2 % (n=3). The LOD and LOQ were 3 and 10 ng/zone for (1) and 2 and 7 ng/zone for (2), respectively. Recovery rate was between 102.6 and 108.8 % for (1) and (2).

      Classification: 32a
      124 016
      Quality by design-based optimization and validation of a high-performance thin-layer chromatography method for the estimation of rivaroxaban in bulk and its pharmaceutical dosage form
      A.S. KHURD*, K.V. DOSHI (*Department of Pharmaceutical Chemistry, Sinhgad Technical Education Society Sinhgad Institute of Pharmacy, Narhe, Pune 411041, Maharashtra, India, amrutakhurd@rediffmail.com)

      J. Planar Chromatogr. 32, 505-510 (2019). HPTLC of rivaroxaban on silica gel with toluene - methanol 7:3. Quantitative determination by absorbance measurement at 250 nm. The hRF value for rivaroxaban was 63. Linearity was between 100 and 600 ng/zone.  Intermediate precision was below 2 % (n=3). The LOD and LOQ were 3 and 9 ng/zone. Recovery rate was between 101 and 102.3 %.

      Classification: 32a
      124 055
      Direct bioautography hyphenated to direct analysis in real time mass spectrometry: Chromatographic separation, bioassay and mass spectra, all in the same sample run
      T.T. HÄBE, M. JAMSHIDI-AIDJI, J. MACHO, Gertrud E. MORLOCK* (*Chair of Food Science, Institute of Nutritional Science, Interdisciplinary Research Center (IFZ), Justus Liebig Univ. Giessen, Heinrich-Buff-Ring 26-32, 35392, Giessen, Germany, Gertrud.Morlock@uni-giessen.de)

      J. of Chromatogr. A 1568, 188-196 (2018). Mass spectra by DART-MS were recorded directly in situ the bioautogram, immediately after direct bioautography (DB). This allowed to detect bioactive analytes within the bioautogram and discriminate microorganism cells and polar bioassay medium ingredients which could otherwise stress the MS system. DB-DART-MS was used for bioactive compounds in cosmetics using the Bacillus subtilis and Aliivibrio fischeri bioassays for detection of Gram-positive and Gram-negative antimicrobials. Planar yeast estrogen screen was used for detection of estrogen-effective compounds. HPTLC-DART-MS of parabens in hand creams either on silica gel with petroleum ether - glacial acetic acid 20:3 or on RP-18W with methanol - water 1:1. Detection under UV 254 and 366 nm. Bioassay by immersing the neutralized chromatograms into the bacterial suspensions.

      Keywords: densitometry HPTLC
      Classification: 4e, 5b
      124 065
      Design of experiment approach for the development and validation of a stability-indicating high-performance thin-layer chromatography method for the estimation of metformin hydrochloride and ursodeoxycholic acid in pharmaceutical dosage form
      R.K. PATEL*, V.K. SHAH (*Pharmaceutical Chemistry Department, K.B. Institute of Pharmaceutical Education and Research, Gandhinagar, Gujarat 382023, India, rajukpatel2006@gmail.com)

      J. Planar Chromatogr. 32, 481-493 (2019). HPTLC of metformin hydrochloride (1) and ursodeoxycholic acid (2) on silica gel with toluene - ethanol - acetone - formic acid 90:40:50:17. Quantitative determination by absorbance measurement at 234 and 700 nm for (1) and (2), respectively. The hRF values for (1) and (2) were 19 and 80, respectively. Linearity was between 5000 and 40000 ng/zone for (1) and 1500 and 12000 ng/zone for (2). Intermediate precision was below 1 % (n=3). The LOD and LOQ were 195 and 592 ng/zone for (1) and 150 and 455 ng/zone for (2), respectively. Recovery rate was 100.5 % for (1) and 99.9 % for (2).

      Classification: 32a
      124 062
      Rapid isolation of a dipeptidyl peptidase IV inhibitor from Fritillaria cirrhosa by thin-layer chromatography–bioautography and mass spectrometry-directed autopurification system
      L. GU, T. TIAN, L. XIA, G. CHOU*, Z. WANG (*Key Laboratory of Standardization of Chinese Medicines, Ministry of Education, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China, chouguixinzyb@126.com)

      J. Planar Chromatogr. 32, 447-451 (2019). HPTLC of Fritillaria cirrhosa on silica gel with ethyl acetate - methanol - ammonia solution - water 180:20:10:1. Bioautography by dipping into a 0.15 mg/mL solution of substrate Gly-Pro-p-nitroanilide hydrochloride in 50 % of ethanol, followed by ethanol removal in the hood and dipping into a 10 U/L DPP IV enzyme solution in TrisHCl buffer (pH 8.2, 70 mM), followed by incubation at 37°C for 40 min. Detection by dipping into a solution of 0.5 % sodium nitrite in 1.2 M hydrochloric acid, followed by drying slightly for 5 min and dipping into 0.05 % N-(1-naphthyl)ethylenediamine dihydrochloride solution. Further analysis by mass spectrometry using a TLC interface. The hRF value for the dipeptidyl peptidase IV inhibitor was 58.

      Classification: 4e, 8b
      124 020
      Unsupervised pattern recognition chemometrics for distinguishing different Egyptian olive varieties using a new integrated densitometric reversed-phase high-performance thin-layer chromatography–image analysis technique
      R. IBRAHIM*, H. ZAATOUT (*Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt, reham.abdelkader@alexu.edu.eg; rehamsaid84@yahoo)

      J. Planar Chromatogr. 32, 411-420 (2019). HPTLC of oleuropein in olive leave samples belonging to 9 different Egyptian olive varieties on RP-18 with methanol - acetonitrile 7:3. Detection by dipping into a methanolic 2-aminoethyldiphenylborane reagent (0.5 %), followed by drying and dipping into methanolic PEG 400 solution (5 %). Qualitative determination under UV light at 366 nm. Captured images were processed using the ImageJ software in order to build 2 separate data matrices (before and after derivatization). Quantitative determination by absorbance measurement at 240 nm. The hRF value for oleuropein was 35. Linearity was between 0.1 and 0.6 µg/zone.  Intermediate precision was below 1 % (n=6). The LOD and LOQ were 0.07 and 0.22 µg/zone. Recovery rate was 100.5 %.

      Classification: 7
      124 021
      A rapid high-performance thin-layer chromatographic method to estimate quercetin in Benincasa hispida (Thunb.) Cogn. fruit pulp
      A. SHAKYA*, S. CHAUDHARY, H. BHAT, N. GOGOI, S. GHOSH (*Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786 004, Assam, India, anshulshakya@dibru.ac.in)

      J. Planar Chromatogr. 32, 467-474 (2019). HPTLC of quercetin in the fresh fruits of Benincasa hispida on silica gel with toluene - ethyl acetate - formic acid 25:20:1. Quantitative determination by absorbance measurement at 262 nm. The hRF value for quercetin was 39. Linearity was between 100 and 1200 ng/zone. Intermediate precision was below 2 % (n=6). The LOD and LOQ were 20 and 60 ng/zone. Recovery rate was 94.3 %.

      Classification: 8a
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