Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      102 022
      Further studies on the neutral lipid content in the feces of BALB/c mice infected with Echinostoma caproni as determined by silica gel HPTLC-densitometry
      D.R. MASSA, B. FRIED*, J. SHERMA (*Department of Biology, Lafayette College, Easton, PA 18042, USA; friedb@lafayette.edu)

      J. Liq. Chromatogr. Relat. Technol. 31, 1871-1880 (2008). HPTLC for the determination of neutral lipid profils using a standard mixture (containing cholesterol, oleic acid, triolein, methyl oleate, cholesteryl oleate) on silica gel (plates with 19 scored lanes and a preadsorbent application area, prewashed by development with dichloromethane - methanol 1:1) with petroleum ether - diethyl ether - acetic acid 80:20:1 in a saturated twin-trough chamber. Detection by spraying with 5 % ethanolic phosphomolybdic acid and heating for 10 min at 115 °C. Quantitative determination by absorbance measurement at 610 nm.

      Classification: 11c
      102 045
      A pharmacognostic study on Sphaeranthus indicus
      K. VIKANI*, R. DANGAR, N. KAPADIA, M. SHAH (*L. M. College of Pharmacy, Dept. of Pharmacognosy, Ahmedabad 380009, India, mamta_b_shah@yahoo.com)

      Journal of Natural Remedies 8(1), 61-67 (2008). During pharmacognostic studies on Sphaeranthus indicus (Asteraceae) the sesquiterpenoid 7-OH-eudesmanolide was isolated. HPTLC of the ethyl acetate soluble fraction of aqueous alcoholic Sphaeranthus indicus extracts, on silica gel with n-hexane - diethyl ether 3:7. The plant extract and the marker (7-OH-eudesmanolide) were chromatographed simultaneously. Quantitative determination by absorbance measurement at 213 nm.

      Classification: 15a
      102 069
      Estimation of berberine in Ayurvedic formulations containing Berberis aristata
      K.K. ROUT, S. PRADHAN, S. K. MISHRA* (*Utkal University, Pharmacognosy and Phytochemistry Division, University Department of Pharmaceutical Sciences, Vani Vihar,Bhubaneswar 751004, Orissa, India; skmishraudps@gmail.com)

      J. AOAC Int. 91, 1149-1153 (2008). HPTLC of berberine on silica gel prewashed with methanol using n-butanol - acetic acid - water 8:1:1 in a twin-trough chamber with chamber saturation for 5 min at 33 °C at 57 % relative humidity. Quantitative determination by absorbance measurement at 350 nm.

      Classification: 22
      102 094
      Validated HPTLC method for simultaneous determination of nebivolol hydrochloride and hydrochlorothiazide from tablets
      L. BHAT*, K. BOTHARA, M. DAMLE (*AISSMS College of Pharmacy, Dept. of Pharmaceutical Analysis, Kennedy road, Pune 411001, India, mrunal.damle@rediffmail.com)

      Indian Drugs 45(12), 948-951 (2008). HPTLC of nebivolol hydrochloride and hydrochlorothiazide on silica gel with ethyl acetate - methanol - ammonia 17:2:1. Absorbance measurement at 280 nm. The method was linear in the range of 500-1500 µg/mL and 100-500 µg/mL for nebivolol hydrochloride and hydrochlorothiazide respectively. Recovery was 99.3-101.9 % for both compounds. The method is suitable for routine quality control.

      Classification: 32a
      102 113
      A HPTLC DENSITOMETRIC DETERMINATION OF ANTIOXIDANT CONSTITUENTS FROM CHYAWANPRASH
      K. Ladha*, R. Kasar, J. Chaudhary, A. Shukla (*Medical Natural Products Research Lab., Pharmaceutical Div., A-282, University Institute of Chemistry Technology, University of Mumbai, Mantunga Mumbai 400019, India, ksladha@udct.org)

      Indian Drugs 45 (7), 536 - 541 (2008). Chyawanprash contains many phytoconstituents, out of which gallic acid, catechin, epicatechin are considered to be responsible for the antioxidant activity and piperine is responsible for the bioavailability enhancing effect. HPTLC with toluene - ethyl acetate - formic acid - ethanol 60:40:3:4. Quantitative determination by absorbance measurement at 254 nm. The hRf values of epicatechin, catechin, gallic acid, and piperine were 13, 32, 44, and 82 respectively. Recovery was 99.0 % for epicatechin, 96.1 % for catechin, 102.5 % for gallic acid and 100.6 % for piperine in Chyawanprash. The results obtained were compared with similar formulations available in the market employing tests for identification and purity determination. The developed method may be considered as an additional tool for quality control of Chyawanprash.

      Classification:
      102 137
      Simultaneous determination of mirtazapine and its three main impurities by a high performance thin layer chromatography/densitometry method
      T.S. REDDY, P.S. DEVI* (*Analytical Chemistry Division, Indian Institute of Chemical Technology, Tarnaka Hyderabad 500007, India; sitadevi@iictuet.org)

      J. Liq. Chromatogr. Relat. Technol. 31, 1204-1212 (2008). HPTLC of mirtazapine (1,2,3,4,10,14b-hexahydro-2-methyl-pyrazino[2,3-c][2-benzazepine]), and three impurities (2-(4-methyl-2-phenyl-piperazin-1-yl)nicotinic acid, [2-(4-methyl-2-phenyl-piperazinyl)-pyridin-3-yl]methanol, and 2-chloronicotinic acid on silica gel with toluene - acetone - methanol 6:2:2 with chamber saturation. Quantitative determination by absorbance measurement at 285 nm. The limit of detection and quantification for mirtazapine was 22 and 75 ng/spot, respectively.

      Classification: 32a
      102 157
      HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHIC ESTIMATION OF LANSOPRAZOLE AND DOMPERIDONE IN TABLETS
      J. Susheel*, M. Lekha, T. Ravi (*Dept. of Pharmaceutical Analysis, College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences, Coimbatore 641044, India)

      Ind. J. Pharm. Sci. 69 (5), 689 - 686 (2007). A simple, fast precise and accurate HPTLC method has been developed for the simultaneous estimation of lansoprazole and domperidone in tablet formulations. This method allows the determination of 100-500 ng/spot of lansoprazole and 100-500 ng/spot of domperidone. HPTLC on silica gel with n-butanol - acetic acid - water 36:12:1:2. Quantitative determination by absorbance measurement at 288 nm. The hRf value of lansoprazole was 78 and of domperidone 21. The limit of detection and quantification for lansoprazole was 10 ng/spot and 40 ng/spot, and for domperidone 30 ng/spot and 65 ng/spot, respectivey. The method was suitable for routine quality control.

      Classification: 32a
      103 029
      Thin-Layer Chromatography and Mass Spectrometry Coupled Using Desorption Electrospray Ionization
      G. VAN BERKEL*, M. FORD, M. DEIBEL (*Organic and Biological Mass Spectrometry Group, Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6131, USA, vanberkelgj@ornl.gov)

      Anal. Chem. 77, 1207-1215 (2005). Desorption electrospray ionization (DESI) was demonstrated as a means to couple TLC with mass spectrometry. HPTLC of rhodamines on RP-2 and RP-8 with methanol - water 4:1 containing 200 mM ammonium acetate. HPTLC of FD&C dyes on RP-18 with water - acetone 7:3 containing 500 mM ammonium acetate. HPTLC of aspirin, acetaminophen and caffeine on silica gel with acetate - acetic acid 99:1. Tracks were scanned by moving the plate under computer control while directing the stationary DESI emitter charged droplet plume at the plate surface. Positioning of the DESI emitter, plate surface, and the atmospheric sampling orifice of the mass spectrometer were found to be crucial for obtaining maximum analyte signal levels. Desorption ionization from all TLC phases was not equivalent.

      Keywords: HPTLC
      Classification: 4e
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