Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

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      120 021
      Selective two-dimensional effect-directed analysis with thin-layer chromatography
      Lena STÜTZ*, S.C. WEISS, W. SCHULZ, W. SCHWACK, R. WINZENBACHER (*Lab. for Oper. Contr. & Res., Zweckverband Landeswasserversorgung, Am spitzigen Berg 1, 89129 Langenau, Germany, stuetz.l@lw-online.de)

      J. Chromatogr. A 1524, 273-282 (2017). Application of effect-directed analysis (EDA) to assess the effects of a substance via in-vitro bioassays, thus to provide information about the relevance of the substance to the ecosystem. Development of selective two-dimensional (2D) HPTLC-EDA to increase the peak capacity and facilitate the identification of effective compounds in environmental samples of high complexity. Selection of effective zones in the first dimension in terms of heart-cutting and transfer to the second dimension through elution head-based extraction. Development and validation of three 2D approaches by using the retardation factors of the first dimension to adjust the mobile phase for the second dimension, achieving the best results in terms of peak capacity and orthogonality. Exemplarily shown for acetylcholinesterase (AChE) inhibition, the analysis of spiked surface water by 2D HPTLC-EDA allowed to assign zones with neurotoxic effects to the corresponding substances. The results proved that the 2D separation reduced the complexity of effective zones and thus facilitated the subsequent identification of effective compounds, and provided knowledge about a substance effect enabled assessment of its relevance to the environment.

      Classification: 3d, 37
      120 039
      Detection of antioxidant butylated hydroxytoluene (BHT) in Antarctic krill (Euphausia superba Dana)
      M. WANG (Wang Meng Yao), D. LIU (Liu Dai Cheng)* (*Key Laboratory of Animal Resistance, College of Life Science, Shandong Normal University, Jinan, P. R. China, liudch@sdnu.edu.cn)

      J. Liq. Chromatogr. Relat. Technol. 40, 725-731 (2017). HPTLC of butylated hydroxytoluene (BHT) in Antarctic krill on silica gel with petroleum ether – ethyl acetate – hexane 8:2:1. Detection by spraying with 5 % aqueous ferric chloride followed by heating at 105 °C for 5-10 min. Quantitative determination by absorbance measurement at 600 nm. The hRF value for BHT was 79. Average recovery was 101.8 %.

      Classification: 7
      120 057
      Detection of steroids and selective androgen receptor
      modulators
      M. GRILL, Melanie BROSZAT* (*CAMAG, Sonnenmattstr. 11, 4132 Muttenz, Switzerland, melanie.broszat@camag.com)

      CBS 118, 1-4 (2017). Screening of steroids and selective androgen receptor modulators (SARMs) in bodybuilding supplements by HPTLC of methanedienone, ibutamoren, and ostarine on silica gel with n-heptane – ethyl acetate 1:1 (steroids) and dichloromethane – methanol 9:1 (SARMs) to the migration distance of 70 mm. Detection by immersion into (1) toluene sulfonic acid reagent (10 % in ethanol) followed by heating at 150 °C for 3 min, or (2) Seebach reagent (5 g phosphomolybdic acid, 2 g cerium sulfate and 12 mL sulfuric acid made up to a volume of 200 mL with water) followed by heating at 110 °C for 5 min. Detection under UV 254 nm, 366 nm and under white light. Densitometric evaluation by multi-wavelength scan at the respective absorption maxima. For example for the steroid testosterone the LOD was 8 ng/zone (absorbance measurement at 250 nm). Direct elution of target zones into the MS and analysis in positive ionization mode.

      Classification: 13
      120 074
      HPTLC for the quantitation of nicotine in liquids for electronic cigarettes
      J.-M. JACQUELIN*, R. HAIZE, S. LO, F. TETARD (*Fabster, 5 Rue des Moissons,
      91670 Angerville, France, jacquelinjmarie@aol.com)

      CBS 118, 13-15 (2017). HPTLC of nicotine in liquids for electronic cigarettes (e-liquids) on silica gel Nano-ADAMANT with dichloromethane – methanol – 28 % ammonia 224:25:1 to the migration distance of 70 mm. Quantitative determination by absorbance measurement at 260 nm. The hRF of nicotine was 38. Confirmation by overlay of UV spectra of standard and sample.

      Classification: 22
      121 002
      Botany, ethnomedicines, phytochemistry and pharmacology of Himalayan paeony (Paeonia emodi Royle
      M. AHMAD*, K. MALIK, A. TARIQ, G. ZHANG, G. YASEEN, N. RASHID, S. SULTANA, M. ZAFAR, K. ULLAH, M. KHAN (*Center for Natural Products Lab, Chengdu Institute of Biology, Sichuan, China, mushtaqflora@hotmail.com)

      J. Ethnopharmacol. 220, 197-219 (2018). Review of traditional uses, phytochemistry, pharmacology, antimicrobial potential, including the literature published on the application of TLC and HPTLC for taxonomic validity of P. emodi.

      Keywords: HPTLC review
      Classification: 1
      121 022
      Unprecedented sensitivity of the planar yeast estrogen screen by using a spray-on technology
      A. SCHOENBORN*, P. SCHMID, S. BRÄM, G. REIFFERSCHEID, M. OHLIG, S. BUCHINGER (ZHAW Life Sciences und Facility Management, Grüental, 8820 Wädenswil, Switzerland)

      J. Chromatogr. A 1530, 185-191 (2017). Development of a new spray-on method for applying yeast cells to HPTLC plates, leading to a much higher sensitivity of the planar yeast estrogen screen (p-YES), which can serve as a highly valuable and sensitive screening tool for the detection of estrogenic compounds in various sample matrices such as water and wastewater, personal care products and foodstuff. HPTLC of sample constituents and direct detection of estrogenic compounds by spraying with yeast cells. This resulted in much sharper signals compared to those in previous publications. Satisfying results were achieved using cultures with cell densities of 1000 FAU with reduced signal broadening, thus lower LOQ for estrogenic compounds, e.g. estrone 2 pg/zone, 17β-estradiol 0.5 pg/zone, 17α-ethinylestradiol 0.5 pg/zone and estriol 20 pg/zone. Demonstration of the possibility of the method to characterize profiles of estrogenic activity of wastewater samples with high quality and reproducibility by using native samples from wastewater or even surface water directly applied on HPTLC plates without the need for prior sample treatment.

      Classification: 4e, 13b, 37c
      121 045
      Characterization and classification of medicinal plants according to their antioxidant profile estimated by thin layer chromatography assisted by chemometric expertise
      I. SIMION, D. CASONI, C. SARBU* (*Department of Chemistry, Faculty of Chemistry and Chemical Engineering, Babe?-Bolyai University, Arany, csarbu@chem.ubbcluj.ro)

      J. Liq. Chromatogr. Relat. Technol. 41, 342-348 (2018). HPTLC characterization and classification of flavonoids in a set of 42 medicinal plants extracts commercially available in Romania on silica gel with ethyl acetate – toluene – formic acid – water 60:3:8:6. Detection by spraying with 2-aminoethyldiphenylborate solution 0.2 % in ethanol, after drying for 30 min at 60 °C. Qualitative identification under UV 254 nm and 365 nm. Plates were immersed into a DPPH solution (0.02 % in ethanol) and images captured with a CCD camera at between 5 and 30 min after plate immersion. A multivariate data analysis including Principal Component Analysis and Cluster Analysis was performed to classify the investigated medicinal plants according to their antioxidant capacity.

      Classification: 8a
      121 065
      Determination of caffeine, theobromine and theophylline in Mate beer and Mate soft drinks by high-performance thin-layer chromatography
      Claudia OELLIG*, J. SCHUNCK, W. SCHWACK* (*Inst. of Food Chem., Univ. of Hohenheim, Garbenstrasse 28, 70599, Stuttgart, Germany)

      J. Chromatogr. A 1533, 208-212 (2018). Development of a rapid method for the determination of caffeine, theobromine and theophylline in Mate beer and Mate soft drinks. Sample preparation through filtration followed by degassing, dilution with acetonitrile in the case of Mate beers for protein precipitation and centrifugation. HPTLC of the extracts on silica gel with acetone – toluene – chloroform 4:3:3, detection and quantification by densitometry at UV 274 nm. The LOD and LOQ were 1 and 4 ng/zone for caffeine, theobromine and theophylline, respectively, and recoveries were close to 100%. Demonstration of the method by applying to the analysis of the concentrations of three methylxanthines in Mate beers as well as Mate beers and Mate soft drinks available from the market proved to be sensitive, accurate and reliable.

      Classification: 21a
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