Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

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      106 145
      Validated chromatographic methods for determination of hydrochlorothiazide and spironolactone in pharmaceutical formulation in presence of impurities and degradants
      Maha HEGAZY*, Fadia METWALY, M. ABDELKAWY, NADA ABDELWAHAB (*Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, 11562 Cairo, Egypt)

      J. Chromatogr. Sci. 49, 129-135 (2011). TLC of hydrochlorothiazide (HCT), spironolactone (SPR) and their impurities and degradation products on silica gel with ethyl acetate - chloroform - formic acid - triethyl amine 70:30:1:1. Quantification by densitometry. The different method parameters were optimized for maximum separation. The method was applied for determination of HCT and SPR in commercial tablets. Statistical comparison with the also performed HPLC method showed that there is no significant difference in the performance of the methods.

      Classification: 32c
      106 171
      Development and validation of a normal-phase HPTLC method for the simultaneous analysis of lamivudine, stavudine and nevirapine in fixed-dose combination tablets
      D. SHEWIYO*, E. KAALE, C. UGULLUM, M. SIGONDA, P. RISHA, B. DEJAEGHER, J. VERBEKE, Y. HEYDEN (Tanzania Food and Drugs Authority, P.O. Box 77150, Dares Salaam, Tanzania)

      J. Pharm. Biomed. Analysis 54, 445-450 (2011). An improved HPTLC method has been developed for simultaneous estimation of lamivudine (LVD), stavudine (STV), and nevirapine (NVP) in fixed dose formulation. HPTLC on silica gel with ethyl acetate - methanol - toluene - 25 % ammonia 12:6:12:1. The hRf value is 24 for LVD, 38 for STV and 69 for NVP. Densitometric evaluation at 254 nm. The method was linear in the range of 42-209 ng/band (LVD), 38-192 ng/band (STV) and 42-208 ng/band (NVP). The recovery values were in the range of 98.4-102.2 % for all three compounds. The method was found suitable for quality control of LVD, STV and NVP in fixed dose formulation.

      Classification: 32c
      107 013
      Studies of Biomphalaria snails infected with larval trematodes using chromatography and atomic spectrometry
      J. SHERMA*, B. FRIED (*Lafayette College, Department of Chemistry, Easton PA 18042-1782, USA)

      B. Fried, R. Toledo (Eds): Biomphalaria snails and larval trematodes. Springer 20119. Chapter 4. This book chapter reviews TLC, HPTLC and other methods for the analysis of larval trematodes from Biomphalaria snails. The analysis of different classes of organic compounds is described: neutral and polar lipids, glycolipids, lutein, beta-carotene, sugars and amino acids. Various TLC and HPTLC phases and developing solvents were used.

      Classification: 1
      107 061
      Optimization of an AMD2 method for determination of stratum corneum lipids
      I. SCHELLENBERG, Kathrin KABRODT* (*Anhalt University of Applied Sciences, Center of Life Sciences, Institute of Bioanalytical Sciences, Strenzfelder Allee 28, 06406 Bernburg, Germany, k.kabrodt@loel.hs-anhalt.de)

      CBS 105, 10-12 (2010). HPTLC of stratum corneum lipids (ceramides, cholesterol, phosphatidylcholine, squalene, sphingomyelin etc.) on silica gel by automated multiple development with a 8-step gradient from methanol to hexane in the AMD2 with pre-conditioning with 4M acetic acid before step 6. Detection by immersion in copper(II)sulfate reagent followed by heating at 170 °C for 8 min. Quantitative determination by absorbance measurement at 600 nm. Phosphatidylcholine and sphingomyelin remain at the start position, all other substances are separated.

      Classification: 11
      107 119
      Development and validation of a method for densitometric analysis of lupeol from Mimosoups elengi
      G.P. GANU*, S.S. JADHAV, A.D. DESHPANDE (*Pad. Dr D.Y. Patil Inst. of Pharm. Sci. & Res., Dep. of Pharmacy, Pimpri, Pune, India)

      Acta Chromatographica 22 (3), 491-497 (2010). HPTLC of lupeol (methanolic Soxhlet extract from the bark of Mimosoups elengi) on silica gel with toluene – ethyl acetate – formic acid 12:2:1. The hRf value of lupeol was 64. Evaluation by densitometry at 220 nm. The linearity was in the range of 1–4 µg/band. The precision was 1.06 and 1.03 %RSD, respectively. Recovery was 97.3 %.

      Classification: 32e
      107 153
      Determination of additives in plastic foils
      Elisabeth DYTKIEWITZ, W. SCHWACK* (*University of Hohenheim, institute of Food Chemistry, Garbenstrasse 28, 70599 Stuttgart, Germany, wolfgang.schwack@uni-hohenheim.de)

      CBS 105, 13-15 (2010). HPTLC of PVC foil samples on silica gel with isooctane – toluene – diethyl ether – ethyl acetate 8:7:4:1 after chamber saturation for 10 min, up to a migration distance of 65 mm. Detection of the biological activity of any compound migrated from the plastic foils in migration studies by dipping in Vibrio fischeri bacteria suspension and documentation with the Bioluminizer. Also direct extraction of additives from plastic foils by the TLC-MS Interface coupled to an Agilent LC-MS system and recording of the eluted additives in the positive ESI mode. Exact masses of unknowns were calculated with MassWorks software allowing their improved specification and thus their confirmation.

      Classification: 35
      108 025
      Spectrodensitometric evaluation and determination of fluconazole and its impurities in pharmaceutical formulation by high-performance thin-layer chromatography
      B. RAMESH, P. NARAYANA, A. REDDY, P. DEVI (*Analytical Chemistry Div, Indian Institute of Chemical Technology, Tarnaka, Hyderabad, (A.P.), India)

      Journal of Pharmacy Research 4(5), 1401-1404 (2011). HPTLC of fluconazole and its structurally related impurities, on silica gel (prewashed with methanol) with n-butanol - water - acetic acid 8:2:1 with chamber saturation for 20 min. The hRf value of fluconazole was 67 and of the two separated impurities 49 (impurity B) and 79 (impurity E). Quantitative determination by densitometry in absorbance mode at 254 nm. The method was linear in the range of 1-6 µg/band for fluconazole and 0.5-2.5 µg/band for both impurities.

      Classification: 6
      108 050
      HPTLC estimation of nateglinide in bulk drug and tablet dosage form
      D. KALE*, R. KAKDE (*Dept. of Pharmaceutical Sciences, R.T.M. Nagpur University, Amravati Rd., Nagpur, India)

      Asian Journal of Chemistry 23(10), 4351-4354 (2011). HPTLC of nateglinide in tablet dosage form on silica gel with n-hexane - methanol - isopropanol 75:15:10. The hRf value was 56. Quantitative evaluation by absorbance measurement at 210 nm. The method was linear in the range of 300-1000 ng/band. The average recovery was 98.5 %.

      Classification: 17a
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