CBS 92, 1-3 (2004). HPTLC of cinchocaine hydrochloride from suppositories on silica gel with 1-butanol - toluene - ethanol - water - 100 % acetic acid 10:8:7:4:1 over 30 mm followed by heating at 110 °C for 10 min. Quantitative determination by fluorescence measurement at 313/>400 nm.Precision is 2 % and recovery 101 %.

CBS 86, 6 (2001). HPTLC of etoposide solution (in 5 % dextrose or 0.9% NaCl) on silica gel in horizontal development chamber in sandwich configuration with diethyl ether - dichloromethane - methanol 24:20:1. Quantitative determination by absorbance measurement at 290 nm.

J. Chinese Trad. Patent Med. (Zhongchengyao) 25 (7), 583-584 (2004). TLC on silica gel with benzene - ethyl acetate - methanol - glacial acetic acid - water 16:10:8:4:3. Detection under daylight or UV light. Identification by finger print technique. TLC screening of many other animal's bile, such as duck bile, chicken bile, cow bile, sheep bile, pig bile and fish bile, etc. Discussion of the possibility of replacing snake bile with some other animal's bile containing similar components.

CBS 93, 5-7 (2004). HPTLC of N,N-diethylethane-1,2-diamine in metoclopramide finished products on silica gel with 32 % ammonia - methanol - dichloromethane 3:15:80 over 40 mm with chamber saturation. Detection by dipping in 0.2 % ethanolic ninhydrin solution for 1 s, followed by drying at 120 °C for 5 min. Quantitative determination by absorbance measurement at 480 nm and evaluation of peak area with polynomial regression. The correlation coefficient of the calibration curve is 0.9995, the residual standard deviation 2.19 %. Intermediate precision is 1.65 %. Recovery for 0.2-1.0 % impurity is 100.5 %. Limit of quantitation is 0.05 % impurity.

J. Planar Chromatogr. 17, 137-142 (2004). TLC of naproxen in pharmaceutical preparations (Naprosyn, Apranax, Aleve, Naproxen) on silica gel with cyclohexane - chloroform - methanol 12:6:1. Quantitative determination at 223 nm. Limit of detection for naproxen is 30 ng. Recovery and repeatability were satisfactory.

J. Planar Chromatogr. 17, 154-156 (2004). HPTLC of pioglitazone hydrochloride ((±)-5-{p-[2-(5-ethyl-2-pyridyl)-ethoxy]benzyl}-2,4-thiazolidinedione hydrochloride) and glimepiride (trans-3-ethyl-2,5-dihydroxy-4-methyl-N-[2-[4-[[[[(4-methylcyclohexyl)amino]-carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide)and atorvastatin as internal standard on silica gel after pre-washing in a twin-trough chamber after pre-saturation with toluene - methanol - ethyl acetate - formic acid 70:20:15:0.1. Evaluation by densitometry at 235 nm.

J. Planar Chromatogr. 17, 164-168 (2004). HPTLC of flupirtine maleate on silica gel with ethyl acetate - methanol - 25 % ammonia 17:2:1 in a saturated developing chamber. Then the developed plate must be dipped for 2 s in 1:3 paraffin - hexane. Dipping increases the fluorescence tenfold and preserves the fluorescence stability for hours. Presentation of a new formula for transforming fluorescence measurements in accordance with Kubelka-Munk theory. The fluorescence signals, the absorption signals, and data from a selected reference are combined in one expression. Only diode-array techniques can measure all the required data simultaneously. The fluorescence calibration curve was linear over the range 300 to 5000 ng per spot.

Chinese J. Trad. Pat. Med. (Zhongchengyao) 26 (9), 716-719 (2004). TLC on silica gel with 1) ethyl acetate - chloroform - formic acid 3:2:1; 2) chloroform - methanol 7:2; 3) petroleum ether (60-90 ºC) - ethyl acetate 7:3. Detection 1) under UV 365 nm; 2) by spraying with 10 % H2SO4 in ethanol and heating at 105 ºC for 5 min; 3) by spraying with vanillin - H2SO4 solution. Identification by fingerprint technique. Quantification of icarrin by HPLC.