Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      121 020
      Quality control of saffron and evaluation of potential adulteration by means of thin layer chromatography-image analysis and chemometrics methods
      H. SERESHTI*, Z. POURSORKH, G. ALIAKBARZADEH, S. ZARRE (*School of Chemistry, College of Science, University of Tehran, Tehran, Iran, sereshti@ut.ac.ir)

      Food Control 90, 48-57 (2018). HPTLC of saffron and its main adulterants (sumac, turmeric, safflower, common madder, quinoline yellow, sunset yellow and tartrazine) on silica gel with 1-butanol – acetic acid – water 4:1:1. Images were captured under visible light and subjected to MATLAB software. The method included image preprocessing capable of identifying such adulteration based on modelling that includes principal component analysis, k-means and chemometric methods such as partial least squares discrimination analysis, variable selection (loading weight and variable importance in projection) and linear discriminant analysis.

      Classification: 3f
      121 058
      Stability-indicating TLC-densitometric assay for methyltestosterone and quantum chemical calculations
      S.G. MUSHARRAF*, Q.U. ARFEEN, F.U. HAQ, Aliya KHATOON, R.A. ALI (*H.E.J. Res. Inst. of Chem., Intern. Center for Chem. & Biol. Sciences, Univ. of Karachi, Karachi 75270, Pakistan, musharraf1977@yahoo.com)

      J. Chromatogr. Sci. 55 (9), 954-960 (2017). Presentation of a simple, cost-effective and rapid stability-indicating assay for densitometric quantification of methyltestosterone, a synthetic testosterone derivative commonly used for the treatment of testosterone deficiency in males, in pharmaceutical formulation. TLC of methyltestosterone on silica gel with hexane – acetone 13:7. Quantitative determination by densitometry at 254 nm in absorbance mode. Evaluation via peak areas using linear regression. The LOD and LOQ were 2 and 6 ng/zone, respectively. Investigation of the degradation of methyltestosterone by applying various stress conditions such as hydrolysis under acidic, basic and neutral conditions, heating in anhydrous conditions and exposure to light. Good separation of the degraded products caused by photodegradation, acidic and basic hydrolysis, and identification of acid degraded product as 17,17-dimethyl-18-norandrosta-4,13(14)-dien-3-one by spectroscopy. Explanation of the reactivity of methyltestosterone under applied stress conditions by quantum chemical calculations. The developed method proved to be repeatable, selective and accurate for quantification of methyltestosterone and can be employed for routine analysis.

      Classification: 14
      121 088
      Development of quantitative HPTLC-densitometry methods following a model approach for transfer of TLC screening methods for pharmaceutical products of atenolol, chloramphenicol, furosemide, glibenclamide, penicillin V potassium, and praziquantel
      B. ZENG, K. NGUYEN, J. SHERMA* (*Department of Chemistry, 326 Hugel Science Center, Lafayette College, 701 Sullivan Road, Easton, PA 18042, USA, shermaj@lafayette.edu)

      J. Liq. Chromatogr. Relat. Technol. 41, 324-328 (2018). TLC minilab protocols were transferred to HPTLC validated methods for the determination of atenolol (1), chloramphenicol (2), furosemide (3), glibenclamide (4), penicillin V potassium (5), and praziquantel (6) on silica gel with methanol – ammonia 100:1 for (1), ethyl acetate – toluene – methanol 15:5:3 for (2), toluene – ethyl acetate – acetic acid 17:13:1 for (3), ethyl acetate – methanol – toluene – ammonia 11:7:1:1 for (4), ethyl acetate – methanol – acetic acid 20:10:1 for (5) and acetone – toluene 14:7 for (6). Qualitative evaluation under UV 254 nm. The hRf values for (1) to (6) were 35, 52, 30, 61, 48 and 65, respectively.

      Classification: 32b
      122 036
      Development of a validated high-performance thin-layer chromatography method for the simultaneous estimation
      of caffeic acid, ferulic acid, ?-sitosterol, and lupeol in Convolvulus pluricaulis Choisy and its adulterants/substitutes
      S. IRSHAD, S. KHATOON* (* Pharmacognosy Division, CSIR-National Botanical
      Research Institute, Post Box No. 436, Rana Pratap Marg Lucknow 226001,
      India, sayyadak@gmail.com; sayyadak@nbri.res.in)

      J. Planar Chromatogr. 31, 429-436 (2018). HPTLC of _x000D_caffeic acid (1), ferulic acid (2), β-sitosterol (3), and lupeol (4) on silica gel with toluene – ethyl acetate – formic acid 85:15:1. Quantitative determination by absorbance measurement at 366 nm for (1) and (2) and 580 nm for (3) and (4). The hRF values for (1) to (4) were 14, 29, 48 and 63, respectively. Linearity ranged between 100-600 ng/zone for (1) and (2) and 200-700 ng/zone for (3) and (4). LOD and LOQ were 49 and 149 ng/zone for (1), 93 and 282 ng/zone for (2), 194 and 589 ng/zone for (3) and 36 and 109 ng/zone for (4), respectively. The intermediate precision was <2 % (n=6). Average recovery was 99.6 % for (1), 99.9 % for (2), 99.2 % for (3) and 99.5 % for (4).

      Classification: 8a, 13c
      122 057
      Estimation of pentacyclic triterpenoids from hydromethanolic extracts of two cytotypes of Achyranthes aspera L
      R. GUPTA, N. BHAT*, A. BANSAL (*Department of Botany, Punjabi University, Patiala,
      Punjab 147002, India, bhattnusrat91@gmail.com)

      by high-performance thin-layer chromatography method. J. Planar Chromatogr. 31, 337-342 (2018). HPTLC of betulinic acid (1), oleanolic acid (2) and lupeol (3) in Achyranthes aspera on silica gel with benzene – ethyl acetate – formic acid 679:227:94 for (1), n-hexane – ethyl acetate – glacial acetic acid 40:20:1 for (2) and n-hexane – ethyl acetate 4:1 for (3). Detection by spraying with anisaldehyde sulfuric acid reagent for (1) and (2) and ceric ammonium sulfate for (3), followed by heating at 105-110°C for 5-10 min. Quantitative determination by absorbance measurement at 530 nm for (1) and (2) and 366 nm for (3). The hRF values for (1) to (3) were 79, 46 and 44, respectively. Linearity was between 2-10 μL/zone. LOD and LOQ were 1 and 4 ng/zone for (1), 1 and 3 ng/zone for (2), and 2 and 5 ng/zone for (3), respectively.

      Classification: 14
      122 078
      Factorial design for development of a high-performance thin-layer chromatography method for the simultaneous estimation of abacavir sulfate, lamivudine hydrochloride, and dolutegravir sodium
      K. DAVE, S. DESAI* (*Department of Quality Assurance, S.S.R. College of
      Pharmacy, S.S.R. Campus, Sayli Road, Silvassa 396230, India, desai6381@gmail.com)

      J. Planar Chromatogr. 31, 489-495 (2018). HPTLC of abacavir sulfate (1), lamivudine hydrochloride (2), and dolutegravir sodium (3) on silica gel with ethyl acetate ‒ ethanol ‒ acetone ‒ ammonia 2239:370:250:75. A factorial design was utilized to aid in method development and optimization. Quantitative determination by absorbance measurement at 267 nm. The hRF values for (1) to (3) were 65, 34 and 26, respectively. Linearity ranged between 4.8-14.4 μg/zone for (1), 2.4-7.2 μg/zone for (2) and 0.4-1.2 μg/zone for (3). LOD and LOQ were 997 ng/zone and 3022 ng/zone for (1), 254 ng/zone and 771 ng/zone for (2), and 100 ng/zone and 304 ng/zone for (3), respectively. The intermediate precision was <2 % (n=3). Recoveries were found in the range of 98.1–101.0 % for (1), 98.3–100.00 % for (2), and 98.5–101.3 % for (3), respectively._x000D_

      Classification: 32a
      55 121
      Two-dimensional thin-layer chromatographic identification of twelve 1,4-benzodiazepines
      M. BAKAVOLI, V. NAVARATNAM, N. NAIR

      J. Chromatogr. 299, 465-470 (1984). TLC separation of a mixture of benzodiazepines on silica with chloroform - acetone 9:1 (first direction), followed by in-situ acidic hydrolysis of the unresolved spots with sulfuric acid in methanol (15 %; 5 mL per component) and subsequent chromatography with dichloromethane - chloroform 1 :1 (second direction). Detection by UV 254 and 366 nm.

      Classification: 32a
      57 079
      Japanese Anal
      O. NARA

      Chem. (Bunseki Kagaku) 34, 612-618 (1985). (Japanese). (High-purity, high-recovery purification of prednisolone by the automatic recrystallization method and its purity evaluation by thin-layer chromatography and by differential scanning colorimetry.) TLC of prednisolone on silica with chloroform - methanol 9:1. Detection by UV 254 nm.

      Classification: 13a, 32c
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