Densitometric analysis of flecainide in tablets. J. Planar Chromatogr. 23, 65-69 (2010). TLC of some antiarrhythmic compounds (disopyramide phosphate, verapamil hydrochloride, flecainide acetate, mexiletine hydrochloride, and tocainide hydrochloride) on RP8 and RP18 silica gel with organic-aqueous mobile phases containing citrate or acetate buffers at different pH in a horizontal chamber. The best separation of individual and mixed drug standards was achieved with tetrahydrofuran - citrate buffer (pH 4.45) 3:7. Flecainide acetate was identified and quantified by UV densitometry at 225 and 310 nm. Linear relationships were obtained between peak height or peak area and amount in the range 6.0 to 12.0 µg/spot, the correlation coefficient r was 0.990. Precision (RSD 1.1-5.9 %) and accuracy (96.2-103.6 %) were satisfactory.

Talanta, 80 (3), 1045-1051 (2010). Review on chromatographic methods for synthetic food dyes, including the following techniques: TLC, HPTLC, traditional column chromatography, HPLC, ion-pair chromatography, RP HPLC, and high performance ion chromatography, demonstrated by using examples in different conditions for each technique.

Int. J. Chem Sci 7(2), 986-992 (2009). A validated HPTLC method is reported for estimation of rofecoxib and tizanidine hydrochloride in combined dosage form. HPTLC on silica gel with methanol - ethyl acetate 1:1. The hRf value of tizanidine was 45 and of rofecoxib 67. Densitometric evaluation at 254 nm. The method was linear in the range of 180-260 ng/band for tizanidine and 2000-3000 ng/band for rofecoxib. Recovery was in the range of 99.5 - 102.5 % for both compounds. The method was suitable for routine quality control of combine dosage form.

Ind. J. Pharma. Sc. 72(4), 513-517 (2010). TLC on silica gel with dichloromethane - methanol - 25 % ammonia 95:10:3. Ofloxacin and ornidazole were well separated. Linearity was in the range of 20-100 ng/band for ofloxacin and 50-250 ng/band for ornidazole. Recovery was in the range of 99.3-100.5 %.

International Journal of ChemTech Research 1(4), 1129-1135 (2009) The marker compound was first isolated by column chromatography over silica gel by elution with toluene - ethyl acetate 17:3. TLC of ethanolic extracts of Syzgium cumini seed on silica gel with toluene - ethyl acetate 17:3. The hRf value of the marker compound was 50. Densitometric evaluation in fluorescence mode at 366 nm. The method was linear in the range of 1-5 µg/band. The extract of the powdered sample contained 7.4 % of the marker compound.

International Journal of Green Pharmacy 3 (1), 47-17 (2009). HPTLC of caffeine on silica gel with ethyl acetate - methanol 9:1. Densitometric quantification at 274 nm. The method was linear in the range of 2-14 µg/band. The sample extracted with 5 % diethyl amine in water gave the maximum yield of caffeine (2.1 %). The proposed chromatography gave the best resolution with caffeine at an hRf value of 40. The method can be used for quality control of tea samples in respect of caffeine contents.

International Journal of ChemTech Research 1(2), 139-141 (2009). TLC on silica gel with toluene - methanol 3:4. The hRf value was 41. Densitometric evaluation at 235 nm. The method was linear in the range of 100-500 ng/band. The average recovery was 98.9 %. The proposed method was suitable for estimation of quetiapine in bulk drug and dosage form.

Eur. J. Med. Chem. 45, 3719-3725 (2010). HPTLC of sulpiride and mebeverine on silica gel with ethanol - methylene chloride - triethyl amine 35:15:1. Quantitative determination by absorbance measurement at 221 nm. The hRF of sulpiride and mebeverine was 42 and 62, respectively. Linearity was between 0.4-1.4 µg/band for sulpiride and 0.2-1.6 µg/band for mebeverine. Detection and quantification limits were 0.02 and 0.3 µg/band for sulpiride and 0.04 and 0.2 µg/band for mebeverine. The intra-day and inter-day precisions had a %RSD lower than 2.6 %.Recoveries (by standard addition) were 99.3 % and 100.7 % for sulpiride and mebeverine, respectively. The proposed method showed comparable statistical results with the standard HPLC method