J. Planar Chromatogr. 18, 203-206 (2005). TLC of primycin (a mixture of related compounds), streptomycin, dihydrostreptomycin on silica gel with A) n-butanol - water - methanol - acetic acid 4:2:1:1; and B) chloroform - methanol - water - 35% formic acid - n-butanol - formaldehyde 160:53:9:6:3:3. When using phase B repeated development improved the resolution. After development the plates were dried in a vacuum chamber at 100 °C. An efficient prewashing technique (with methanol - 35 % formic acid 1:1 followed by drying with hot air) made the TLC plates suitable for densitometric measurements at short wavelengths. Quantitative determination by absorbance measurement at 200 nm.

J. Pharm. Biomed. Anal. 40, 68-74 (2006). Two TLC methods have been developed for the screening of fake (counterfeit) drugs of macrolide antibiotics. TLC on silica gel with ethyl acetate - n-hexane - ammonia 20:3:3 for 14 membered macrolides and trichloromethane - methanol - ammonia 100:5:1 for 16 membered macrolides. Detection by spraying with KMnO4 solution. Different chromatographic conditions were standardized and results of color reactions and TLC were correlated to judge the counterfeiting. The method was evaluated in five different laboratories in China.

Hosp. Pharm. (Zhongguo Yiyuan Yaoxue Zazhi) 25 (9), 894-896 (2005). TLC of the extracts on silica gel plates with acetone - ethanol - hydrochloric acid 10:6:1. Detection by spraying with potassium iodobismuthate solution. Identification by comparison with the standard. Quantification by densitometry at 510 nm. Validation of the method by investigation of linearity range (2.2 µg - 10.8 µg, r = 0.9994); precision (RSD = 1.05 %, n = 5); reproducibility of five time assay towards the same sample (RSD = 0.31 %); and standard addition recovery (98.1 %, RSD = 2.15 %, n = 5). The results for five real life samples are given.

J. AOAC Int. 87, 1319-1322 (2004). TLC of chlorpheniramine and pheniramine maleate in combination with other drugs in pharmaceutical preparations of tablets, syrups, eye and ear drops etc. on silica gel with cyclohexane - chloroform - methanol - diethylamine 9:8:1:2. Detection under UV light at 254 nm and quantitative determination by scanning at 260 nm. Recoveries of CPM and PM were 100.1 +/- 0.8 % and 100.1 +/- 0.9 %, respectively.

Indian Drugs 42 (8), 511-515 (2005). HPTLC carvedilol in tablets on silica gel with toluene - methanol - ethyl acetate - ammonia 40:10:5:1. Quantitative determination by absorbance measurement at 254 nm. The method was linear in the range of 50-250 µg/µL with recovery of 98.5-100.2 %. Stability was studied during and after development. Accuracy, precision, and specificity of the method were established.

CBS 96, 14-15 (2006). TLC of glibenclamide as adulterant in antidiabetic herbal drugs, on silica gel with toluene - ethyl formate - formic acid 5:4:1 in a saturated twin trough chamber over 150 mm. Detection under UV 365 nm, quantification of the image with VideoScan software. Rf of glibenclamide is 0.58. Results were compared with those obtained by UV spectrophotometry and HPLC and showed good correlation.

J. Chinese Trad. Patent Med. (Zhongchengyao) 27(5), suppl. 1-3 (2005). TLC of cinnamyl aldehyde in Chongcao Yangshen capsules on silica gel with petroleum ether (60 - 90 ºC) - ethyl acetate 6:1. Detection by spraying with 2,4-dinitrophenylhydrazine reagent. Quantification by densitometry at 514 nm. Validation of the method by investigation of its linearity range (0.0.3 µg - 2.5 µg, r = 0.99); precision (RSD = 1.1 %, n = 5); its reproducibility of five time assay towards the same sample (RSD = 1.2 %); standard addition recovery (99.9 %, RSD = 1.3 %, n = 5). The results for three batches of real life samples are given. Discussion of the application of the procedures for the quality control of the medicine.

J. Planar Chromatogr. 19, 443-448 (2006). HPTLC of diclofenac sodium and paracetamol (with aceclofenac as internal standard) on silica gel, pre-washed with methanol, in a presaturated twin-trough chamber with toluene - ethyl acetate - methanol - formic acid 50:40:10:1. Quantitative determination by absorbance measurement at 260 nm. The method was validated regarding accuracy and precision.