Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

Page
      107 096
      Development and validation of HPTLC and derivative spectroscopic method for simultaneous estimation of nebivolol and hydrochlorothiazide in combined dosage form
      J. SHAH*, H. PATEL, S. PATEL, S. PANCHOLI (*Dept. of Pharmaceutical Analysis, Babaria Institute of Pharmacy, Vadodara-Mumbai NH#8, Varnama, Vadodara 391240, Gujarat, India)

      62nd Indian Pharmaceutical Congress Abstract No. F-258 (2010). TLC of nebivolol HCl and hydrochlorothiazide on silica gel with methanol – chloroform – toluene – triethylamine 10:25:14:1. Quantitative determination by absorbance measurement at 284 nm. The hRf value of nebivolol was 78 and of hydrochlorthiazide 41. The method was linear in the range of 5-100 ng/band and 20-140 ng/band for nebivolol HCl and hydrochlorothiazide, respectively. Recovery was in the range of 98.8-100.0 % for both drugs.

      Classification: 23e
      107 116
      Simultaneous TLC-densitometric analysis of atenolol and lercanidipine hydrochloride in tablets
      P.V. DEORE*, A.A. SHIRKHEDKAR, S.J. SURANA (*R.C. Patel College of Pharmacy, Department of Pharmaceutical Chemistry Shirpur Dist. Dhule (M.S.), India, 425 405)

      Acta Chromatographica 20(3), 463-473 (2008). TLC on silica gel with toluene – methanol – triethylamine 35:15:1. The hRf of atenolol and lercanidipine hydrochloride was 24 and 68, respectively. Detection and quantitative determination by absorbance measurement at 275 nm. The linearity was in the range of 2-12 µg/band for atenolol and 400–2400 ng/band for lercanidipine hydrochloride. The recovery was 98.9 % for atenolol and 99.7 % for lercanidipine hydrochloride.

      Classification: 32c
      107 135
      (Study on the analysis of Ziyinzhike capsules by thin-layer chromatography) (Chinese)
      Y. PAN* (Pan Yanrong), X. WEI (Wei Xiaorui) (*Xuchang Inst. for Drug Contr. of Henan Prov., Henan, Xuchang 461000,China)

      J. Chinese Modern Med. & Pharm. 18 (1), 40-42 (2011). TLC on silica gel with petroleum ether (60-90 ºC) – ethyl acetate 1:1. Detection under UV 254 nm. Identification by comparison of the fingerprint of the main component, Rehmanniae Radix.

      Classification: 32e
      108 012
      The start-to-end chemometric image processing of 2D thin-layer videoscans
      L. KOMSTA*, L. CIESLA, Anna BOGUCKA-KOCKA, Aleksandra JÓZEFCZYK, J. KRYSZEN, Monika WAKSMUNDZKA-HAJNOS (*Dep. of Med. Chem., Med. Univ. of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland)

      J. of Chromatogr. A 1218 (19), 2820-2825 (2011). A unified procedure for image preprocessing of 2D TLC videoscans saved as JPG files is proposed for further supervised or unsupervised chemometric analysis. The procedure was based on open source software and included denoising using a median filter, baseline removal with the rollerball algorithm and nonlinear warping using spline functions. The application of the proposed procedure enabled filtration of random differences between images, such as changes in the intensity of the background as well as differences in the location of the zones. After the preprocessing only the zone intensity had an influence on the statistical analysis by principal component analysis (PCA) or other techniques. The proposed technique was successfully applied for the determination of the differences between three Carex species based on the 2D videoscans of the extracts.

      Classification: 3f
      108 036
      Validated high-performance thin-layer chromatographic method for estimation of olopatadine hydrochloride as bulk drug and in ophthalmic solutions
      M. ANAND, Purvi GANDHI, Nancy PANDITA, S. GANDHI, P. DESHPANDE* (*Dept. of Pharmaceutical Chemistry, School of Pharmacy & Technology Management, SVKMs NMIMS University, Vile-Parle (w) Mumbai, India)

      International Journal of ChemTech Research 2(3), 1372-1375 (2010). TLC of olopatadine hydrochloride on silica gel aluminum foil with methanol - water - glacial acetic acid 40:10:1 with chamber saturation for 20 min. The hRf value was 37. Quantitative determination by densitometry in absorbance mode at 247 nm. The method was linear in the range of 200-1200 ng/band. The average recovery was 100.5 %.

      Classification: 11a
      108 066
      Development and validation of a high-performance thin-layer chromatographic method for determination of ofloxacin residues on pharmaceutical equipment surfaces
      Irena VOVK*, B. SIMONOVSKA (*National Institute of Chemistry, Laboratory for Food Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia, and EN-FIST Centre of Excellence, Dunajska cesta 156, SI-1000 Ljubljana, Slovenia; irena.vovk@ki.si)

      J. AOAC Int. 94, 735-742 (2011). HPTLC and TLC of ofloxacin on silica gel with ethanol - conc. ammonia 4:1 in a horizontal chamber. Quantitative determination by fluorescence measurement at 313 nm. Simulated samples at a residue level of 1 mg/m² were prepared by spreading the calculated amount of ofloxacin solution on 1, 5, and 10 dm² stainless steel surfaces. The hRf of ofloxacin was 56. The mean recovery (n = 6) was 88.6-95.3 % with a CV of 3.8-4.9 %. The LOD was 0.6 ng/zone and the LOQ was 2 ng/zone, but it was shown that these can be lowered by immersion of the developed plate into a solution of liquid paraffin - n-hexane 1:2 to approximately 0.3 and 0.9 ng/zone. The repeatability (system precision) was 4.2 % for 2 ng, and 3.7 % for 20 ng. The recovery was between 88.6-95.3 %.

      Classification: 28a
      108 089
      Optimization and qualitative determination of Mezereon homeopathic tincture by applying rapid horizontal TLC
      B. GEHRMANN, M.F. MELZIG (*Einhorn-Rats-Apotheke, Markt 10-12, 25813 Husum, Germany)

      Planta Med. 75, 1000 (2009). TLC and HPTLC of Mezereon (Daphne mezereum) bark extracts and scopoletin, umbelliferone, mezerein, and daphnetoxin on silica gel with various mobile phases containing toluene, ethyl acetate, and formic acid at different proportions. Detection under UV 254 and 366 nm and visible light. The applied procedure may be proposed for an updated and optimized TLC identification test of the homeopathic monograph of Daphne mezereum L.

      Classification: 32e
      108 108
      Simultaneous densitometric determination of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol in some commercial gingers
      F. MELIANITA, J. WITHA, S. ARIFIN, W. KARTINASARI, G. INDRAYANTO* (*Department of R&D, Bernofarm Pharmaceutical Company, Sidoarjo, Surabaya, Indonesia, and Assessment Service Unit, Faculty of Pharmacy, Airlangga University, Jl. Dharmawangsadalam, Surabaya 60286, Indonesia, gunawanindrayanto@yahoo.com)

      J. Liq. Chromatogr. Relat. Technol. 32, 567-577 (2009). HPTLC of 6-gingerol (1), 8-gingerol (2), 10-gingerol (3), and 6-shogaol (4) in commercial gingers on Lichrosphere silica gel with toluene - ethyl acetate 3:1. Detection by spraying with anisaldehyde-sulfuric acid reagent, followed by heating at 120 ºC for 10 min. Quantitative determination by absorbance measurement at 577 nm. Linearity was between 96-480 ng for (1), 39-196 ng for (2), 49-242 ng for (3) and 50-256 ng for (4). Limits of detection and quantification were 26 and 77 ng/zone for (1), 16 and 47 ng/zone for (2), 17 and 50 ng/zone for (3) and 33 and 99 ng/zone for (4). %RSD of repeatability and intermediate precision were below 5 %. Recoveries were between 99.7 and 104 % for (1)-(4).

      Classification: 32e
Page