Indian J. Pharma Educ. Res. 42(1), 32-35 (2008). HPTLC of metoprolol succinate on silica gel with toluene - methanol - triethylamine 30:50:3. Quantitative determination by absorbance measurement at 274 nm. The hRf value was 40. The method was linear in the range of 5-10 ng/spot. The limit of detection and quantification was 430 ng/spot and 1310 ng/spot respectively. The method was suitable for routine quality control.

Ind. J. Pharm. Sci. 70(3), 398 - 400 (2008). HPTLC of ibuprofen and pseudoephedrine HCl on silica gel with tert-butanol - ethyl acetate - acetic acid - water 7:4:2:2. Quantitative determination by absorbance measurement at 254 nm. The hRf value of pseudoephedrine was 68 and of ibuprofen 91. The method was linear in the concentration range of 45.6 - 75.6 µg/mL for ibuprofen and 6.8 - 11.3 µg/mL for pseudoephedrine. The recovery was between 100.7 and 101.0 % for both compounds. The method was suitable for routine quality control.

60th Indian Phamaceutical Congress PA-132, (2008). HPTLC of lamivudine and zidovudine on silica gel with acetone - methanol - toluene 2:1:2. Quantitative determination by absorbance measurement at 273 nm. The method was suitable for routine quality control of both drugs in combined dosage form.

J. Liq. Chromatogr. Relat. Technol. 31, 1204-1212 (2008). HPTLC of mirtazapine (1,2,3,4,10,14b-hexahydro-2-methyl-pyrazino[2,3-c][2-benzazepine]), and three impurities (2-(4-methyl-2-phenyl-piperazin-1-yl)nicotinic acid, [2-(4-methyl-2-phenyl-piperazinyl)-pyridin-3-yl]methanol, and 2-chloronicotinic acid on silica gel with toluene - acetone - methanol 6:2:2 with chamber saturation. Quantitative determination by absorbance measurement at 285 nm. The limit of detection and quantification for mirtazapine was 22 and 75 ng/spot, respectively.

Ind. J. Pharm. Sci. 70(3), 366-368 (2008). TLC of rabeprazole and itopride hydrochloride in tablets on silica gel with n-butanol - toluene - ammonia 17:1:2. Quantitative determination by absorbance measurement at 288 nm. The hRf value of rabeprazole was 23 and of itopride hydrochloride 75. Linearity was found to be in the range of 40 - 200 ng/spot for rabeprazole and 300-1500 ng/spot for itopride hydrochloride. The limit of detection and quantification for rabeprazole was 10 and 20 ng/spot and for itopride hydrochloride 50 and 100 ng/spot, respectively. The method is suitable for simultaneous anlysis of both the drugs in dosage form.

Acta Chromatographica 21 (1), 83-93 (2009). HPTLC of quetiapine fumarate on silica gel with toluene - methanol 4:1. The hRf value of quetiapine fumarate was 37. Quantitative determination by absorbance measurement at 254 nm. There was no chromatographic interference from tablet excipients. The drug is susceptible to treatment with acid and alkaline hydrolysis, oxidation, and photodegradation. The method was able to separate the degradation products from the pure drug, it can be used for stability tests.

J. Planar Chromatogr. 22, 137-140 (2009). HPTLC of fluvastatin and photochemical decomposition products on RP-18 with phosphate buffer (pH 4.0) - methanol 3:17 at 4 +/- 0.5 °C with chamber saturation and under light protection. Before development the plates were thermostated for 10 min in the dry chamber. Detection of fluvastatin and its photoproducts under UV 254 nm. Isolation of photoproducts by preparative TLC on RP-18.

J. Planar Chromatogr. 21, 251-258 (2008). TLC of tiaprofenic acid, ketoprofen, naproxen, dexibuprofen, flurbiprofen, alminoprofen, and ibuprofen on silica gel with chloroform - acetone - toluene 12:5:2 and chloroform - ethyl acetate 1:1. Quantitative determination by absorbance measurement at 225 nm (for naproxen, dexibuprofen, and ibuprofen) and at 270 nm (for tiaprofenic acid, ketoprofen, flurbiprofen, and alminoprofen).