J. Chinese Trad. Patent Med. (Zhongchengyao) 27 (3), 279-282 (2005). TLC of the extracts of the title Chinese traditional patent medicine on silica gel with 1) ethyl acetate - methanol - ammonia 17:2:1; 2) n-butanol - glacial acetic acid - water 19:5:5. Detection 1) under UV 365 nm; 2) by spraying with ninhydrin solution followed by heating at 105 ºC until the spots are visualized. Identification by fingerprint technique. Quantification of paracetamol and pseudoephedrine arginine by HPLC.

J. Pharm. Biomed. Anal. 39, 801-804 (2005). HPTLC on silica gel with chloroform - methanol 9:1. Quantitative determination by absorbance measurement at 265 nm. The hRf values of stavudine (SV), lamivudine (LV) and nevirapine (NV) were 25, 67 and 87 respectively. The method was linear within the range of 0.01-0.06 mg/mL, 0.05-0.30 mg/mL and 0.06-0.40 mg/mL for SV, LV, and NV respectively, recovery rates were between 98.2 and 99.9 %. The HPTLC method was compared with the UV and HPLC methods. Accuracy, precision and ruggedness of the method were established.

J. Pharm. Biomed. Anal 39, 132-138 (2005). A simple, selective, precise and stability-indicating HPTLC method of analysis of curcumin both as a bulk drug and in formulations was developed and validated. HPTLC on silica gel with chloroform-methanol 37:3. This system was found to give compact spots of curcumin (Rf 0.48). Densitometric analysis of curcumin in the absorbance mode at 430 nm. The linear regression analysis data for the calibration plots showed good linear relationship with r =0.996 and 0.994 via peak height and peak area, respectively, in the concentration range of 50-300 ng per spot. The method was validated for precision, recovery, robustness. The LOD and LOQ were 8 and 25 ng per spot, respectively. Curcumin was subjected to acid and alkali hydrolysis, oxidation and photodegradation.

Indian Drugs 42 (6), 345-352 (2005). TLC fingerprint identification of methanolic extracts of Adhatoda vasica, Lawsonia inermis and Alkanna tinctoria, on silica gel. For Lawsonia inermis and Alkanna tinctoria the developing solvent toluene - acetone - acetic acid 90:10:1 was used, and for Adhatoda vasica n-hexane - acetone - diethyl ether 3:1:1 for. Detection of alkannin by spraying with 10 % methanolic KOH.

Indian J. Pharm. Sci. 67 (2), 182-186 (2005). HPTLC of atorvastatin calcium in its commercial single component tablet formulations (10 mg/tablet), on silica gel with benzene-methanol 7:3. The Rf value was 0.46. Quantitative determination by absorbance measurement at 281 nm. The method was validated in terms of linearity (200-600 ng/spot), precision (intraday variation: 0.25 - 1.01 %, interday variation: 0.21 - 0.88 %), accuracy and specificity. The LOD for atorvastatin calcium was 40 ng/spot, the LOQ was 200 ng/spot. The proposed method was successfully applied to determine atorvastatin calcium content of 10 individual tablet units of two market formulations after extracting atorvastatin calcium with methanol. All formulations were compliant with USP specifications (RSD less than or equal to 6 %) of the content uniformity test. The proposed HPTLC method can analyse ten or more formulation units simultaneously on a single plate and provides a faster and cost effective quality control tool for routine analysis of atorvastatin calcium formulation.

J. Planar Chromatogr. 19, 288-296 (2006). TLC of metformin hydrochloride, pioglitazone hydrochloride, rosiglitazone maleate, gliclazide, and glibenclamide on silica gel in a pre-equilibrated chamber at 26 - 30 °C with toluene - ethyl acetate - methanol 17:2:17 and n-butanol - acetic acid - water - methanol 12:4:1:2. Detection by exposure to iodine vapor. Highly reproducible RF and compact spots were obtained in normal-phase TLC which was found to be the least expensive method.

Anal. Sci. 22, 743-745 (2006). HPTLC of gatifloxacin and ornidazole on silica gel with n-butanol – methanol 8:1 and 1 drop ammonia with chamber saturation for 45 min. Quantitative determination by absorbance measurement at 302 nm. Linearity of determination of gatifloxacin is 100 – 500 ng and of ornidazole 250 – 1250 ng, with a correlation coefficient of more than 0.9850. The intra-day and inter-day coefficients of variation are found to be in the range of 0.68 - 2.58 % and 0.37 - 3.62%, respectively.

J. Liq. Chromatogr. Relat. Technol. 28, 3243-3254(2005). TLC of tranexamic acid (trans-4-(aminomethyl)cyclohexane carboxylicacid) on silica gel with n-butanol - glacial acetic acid - water 4:1:1 in a twin-trough chamber with chamber saturation. Detection by dipping in a 0.25 % solution of ninhydrin in ethanol and heating at 100 °C for 1 min. Quantitation by densitometry in absorbance mode at 488 nm.