Ind. J. Pharm. Res. 6 (4), 205-207 (2007). HPTLC of itraconazole on silica gel with toluene - acetone - triethylamine 30:30:1. Detection at 270 nm. The hRf value of itraconazole was 62. Linearity was between 0.2 and 0.6 µg. The market formulation contained itraconazole amounts of 99.6 % via peak height and 100.2 via peak area, respectively. Recovery (by standard addition) was 99.4 % and 100.3 % respectively.

Ind. J. Pharm. Sci. 69 (5), 684-686 (2007). HPTLC of lansoprazole and domperidone in tablet formulations on silica gel with n-butanol - acetic acid - water 186:5:10. Densitometric analysis in absorbance mode at 288 nm. The calibration covered the range of 100 to 500 ng/spot for both substances. The hRf value of lansoprazole and domperidone was 78 and 21, respectively. The limit of detection and quantification for lansoprazole was 10 and 40 ng/spot and for domperidone 30 and 65 ng/spot, respectively. The method is suitable for routine quality control.

J. Chromatogr. A 1207 (1-2), 155-159 (2008). HPTLC of secoisolariciresinol diglucoside in flaxseed on RP18W with methanol - 0.1 % formic acid 2:3, using the alkaline hydrolysis in aqueous medium of undefatted samples. Quantitative determination by absorbance measurement at 282 nm. Validation of the method following the protocol proposed by the Société Francaise des Sciences et Techniques Pharmaceutiques lead to a dependable and high throughput procedure well suited for routine application. Linearity was between 321–1071 ng/zone and the RSD of repeatability and intermediate precision did not exceed 3.6 %.

J. AOAC Int. 91, 1331-1338 (2008). HPTLC of ciprofloxacin (1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(piperazin-1-yl)quinoline-3-carboxylic acid hydrochloride) and degradation products (7-[(2-aminoethyl)amino]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid and 7-amino-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid) on silica gel with chloroform - methanol - 25 % ammonia 43:43:14. Detection with 0.3 % methanolic ninhydrin solution and dimethylaminobenzaldehyde and quantitative determination by absorbance measurement at 277 nm.

60th Indian Pharmaceutical Congress PA-204, (2008). HPTLC of carvedilol on silica gel with methanol - ethyl acetate 13:7. The hRF was 49. Quantitative determination by absorbance measurement at 242 nm. Linearity was between 200-1000 ng/spot. The recovery was 98-102 %. The method was suitable for routine quality control of the drug in formulation.

60th Indian Pharmaceutical Congress PA-207, (2008). HPTLC of glibenclamide, rosiglitazone and metformin in combined dosage form on silica gel with methanol - tetrahydrofuran - water - acetate acid 40:9:10:1 with chamber saturation for 10 min. ThehRF values were 56, 60, and 80 for glibenclamide, rosiglitazone, and metformin respectively. Quantitative determination by absorbance measurement at 245 nm. The method was linear in the range of 200-1000 ng/zone (glibenclamide, rosiglitazone) and 120-600 ng/zone (metformin). Recovery was 0.97-99.3 % for all the three compounds. The method was suitable for simultaneous estimation of all three compounds in dosage form.

60th Indian Pharmaceutical Congress PA-87, (2008). HPTLC of carvedilol on silica gel with toluene - chloroform - methanol - acetic acid 20:20:10:1. Densitometric evaluation at 240 nm. The method was linear in the range of 50-1000 ng/spot. The method could effectively separate the drug from its degradation products (acid, base, oxidaline, photodegradation). The kinetic studies confirmed that the drug is more degraded in alkaline medium than in acidic medium.

J. AOAC Int. 91, 1237-1243 (2008). HPTLC of zinc bis(O,O’-diisobutyl dithiophosphate), zinc bis(O,O’-didodecyl dithiophosphate), and Aglamol 99 on RP-2 by automated multiple development with methanol - water - acetic acid 6:3:2 for 25 mm, then acetonitrile - water 11:9 for 60 mm, and again acetonitrile - water for 80 mm, or on silica gel with a 14-step gradient based on toluene. For derivatization, the plate was dipped in a solution of 0.05 % primuline in acetone - water 4:1 for 1 s and immediately dried in warm air. Quantitative determination by fluorescence measurement at 366/>400 nm and by absorbance measurement at 220 nm. HPTLC-ATR-IR and HPTLC-FTIR, as well as HPTLC/DART-MS and HPTLC/ESI-MS were applied for identification.