Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

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      104 054
      (Determination of gentamycin and the related compounds by thin-layer chromatography) (Chinese)
      L. YANG (Yang Lihong)*, CH. HU (Hu Changqin), W. LIU (Liu Wenying) (*China Pharm. Univ., Nanjing 210009, China)

      Chinese J. Pharm. Anal. 26 (2), 221-224 (2006). HPTLC of gentamycin and related compounds on silica gel with chloroform – methanol – 25 % ammonia 5:7:6. The main compound is well separated from the impurities. Quantification by densitometry at 485 nm. Linearity was between 4.0 – 40 ng/spot (r2 = 0.99) and the limit of detection was at the low ng level.

      Classification: 28a
      104 106
      Stability-indicating HPTLC determination of ambroxol hydrochloride in bulk drug and pharmaceutical dosage form
      P.S. JAIN (R.C. Patel College of Pharmacy, Karwand Naka, Shirpur Dist. Dhule 425 405 (M.S.) India)

      J. Chromatogr. Sci. 48 (1), 45-48 (2010). HPTLC of ambroxol hydrochloride on silica gel with methanol - triethylamine 2:3. The hRf value of ambroxol was 53. Quantification by absorbance measurement at 254 nm. Linearity was given in the range of 100-1000 ng/spot with r2 = 0.9966 (via peak area). The limits of detection and quantitation were 10 and 30 ng/spot, respectively. Ambroxol hydrochloride was susceptible to degradation under oxidation and thermal stress conditions. The method is suitable for purity testing of the drug as it detects the related impurities.

      Classification: 32c
      104 231
      (Determination of astragaloside in Tianjian capsule) (Chinese)
      T. XONG (Xong Ting) (Pharm. Coll., Wuhan Univ., Wuhan, Hubei 430072, China)

      Chinese J. Hospit. Pharm. 29 (4), 336-338 (2009). TLC of astragaloside in Tianjian capsules on silica gel with chloroform - methanol - water 13:6:2. Detection by spraying with 5 % sulfuric acid in ethanol followed by heating at 105 ºC until coloration. Quantification by densitometry at 515 nm. The linearity was between 0.98 and 4.90 µg/spot (r2 = 0.998), the %RSD was 2.4 % (n = 6) within plate and 2.3 % (n = 6) inter-plate, standard addition recovery was 99.2 % with RSD = 1.7 % (n = 6).

      Classification: 32e
      105 019
      Simultaneous HPTLC analysis of flavonoids in the leaves of three different species of bamboo
      J. SUN (Sun Jia) , Y. YUE* (Yue Yongde), F. TANG (Tang Feng), X. GUO (Guo Xuefeng) (*International Centre for Bamboo and Rattan, No. 8 Futong Dongdajie), Wangjing, Chaoyang District, Beijing 100102, Cina; yueyd@icbr.ac.cn)

      J. Planar Chromatogr. 23, 40-45 (2010). HPTLC of flavonoids (vitexin, isovitexin, orientin, isoorientin, rutin) on polyamide at 23 +/- 2°C and 40 % relative humidity with the three-component mobile phase A-B-C 33:67:8, where A is dodecyl sulfate - n-butanol - n-heptane 147:158:28, B is water, and C is formic acid. The solvent mentioned gave the best resolution of vitexin (hRf 61), isovitexin (hRf 21), orientin (hRf 28), isoorientin (hRf 34), and rutin (hRf 52). Detection by spraying with 1 % aluminium trichloride in ethanol followed by waiting for approximately 1h. Quantitative determination by fluorescence measurement at 366 nm. Precision was found to be 0.98, 0.91, 1.02, 1.04 and 0.87 % for isovitexin, rutin, orientin, isoorientin, and vitexin, respectively. Average recoveries (at three different concentrations) were between 98.9 and 100.6 % from P. pubescens, P. glauca and P. yixingensis.

      Classification: 8a
      105 084
      Usefulness of transgenic luminescent bacteria in direct bioautographic investigation of chamomile extracts
      Ágnes M. MÓRICZ*, E. TYIHÁK, P. G. OTT (*Plant Protection Institute, Hungarian Academy of Sciences, Herman O. u. 15, 1022 Budapest, Hungary; moricz_am@nki.hu)

      J. Planar Chromatogr. 23, 180-183 (2010). TLC of chamomile extracts on silica gel with benzene - ethyl acetate 19:1 or chloroform - methanol - water 40:10:1 in an unsaturated chamber. Detection at 254 and 366 nm. For bioautographic evaluation bioluminescent Bacillus subtilis or Pseudomonas syringae pv. maculicola were used; visualization by dye a reagent was achieved by dipping the plate in an aqueous solution of MTT. Quantitative determination by densitometric scanning at 300 nm (before biological detection) or at 590 nm (after visualization of the bioautogram with MTT).

      Classification: 32e
      106 072
      TLC chromatographic-densitometric assay of ibuprofen and its impurities
      Malgorzata STAREK*, J. KRZEK (*Department of Inorganic and Analytical Chemistry, Jagiellonian University, Collegium Medium, 9 Medyczna Str., 30-688 Cracow, Poland)

      J. Chromatogr. Sci. 48(10), 825-829 (2010). TLC of ibuprofen and its impurities in pharmaceutical preparations on silica gel with toluene - ethyl acetate - glacial acetic acid 17:13:1. Quantification by densitometry. The limit of detection and quantification ranges from 0.13-0.27 µg/zone. The recovery is 96.8-99.0 % for the individual constituents. The method is suitable for routine quality-control analysis of pharmaceuticals containing ibuprofen.

      Classification: 11a
      106 143
      Phytochemical investigation and immunomodulatory activity of Lagenaria siceraria fruits
      A. GANGWAL*, S. PARMAL, N. SHETH (*Dept. of Pharmaceutical Sciences, Suarashtra University, Rajkot 360005, India)

      Journal of Natural Remedies 10(2), 170-174 (2010). The powdered plant material was defatted, extracted with methanol, concentrated and successively extracted with ethyl acetate and n-butanol. The resulting fractions were concentrated and subjected to chromatographic fingerprint analysis of the phytoconstituents, i.e. alkaloids, saponins, tannins, flavonoids, anthraquinones and sterols. TLC on silica gel with n-butanol - acetic acid - water 4:1:5 for the ethyl acetate fraction and with chloroform - methanol 9:1 for the n-butanol fraction. Densitometric evaluation at 254 nm and 366 nm for the n-butanol fraction and at 290 nm for the ethyl acetate fraction. Derivatization with vanillin-sulfuric acid reagent for the n-butanol fraction and with AlCl3 reagent for the ethyl acetate-fraction, evaluation at 600 nm. The n-butanol fraction contained sterols and saponins, the ethyl acetate fraction flavonoids.

      Classification: 32e
      106 182
      Different approaches of impregnation for resolution of enantiomers of atenolol, propranolol and salbutamol using Cu(II)-L-amino acid complexes for ligand exchange on commercial thin-layer chromatographic plates
      R. BHUSHAN*, Shivani TANWAR (*Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee 247667, India)

      J. Chromatogr. A 1217(8), 1395-1398 (2010). TLC of atenolol, propranolol and salbutamol and their enantiomers by using different modes of loading/impregnating the Cu(II) complexes of L-proline, L-phenylalanine, L-histidine, N,N-dimethyl-L-phenylalanine, and L-tryptophan on silica gel with 1) the Cu(II)-L-amino acid complex as chiral mobile phase additive, 2) ascending development of plain commercial plates in the solutions of Cu complex, and 3) using a solution of Cu(II)acetate as mobile phase additive for the commercial TLC plates impregnated by development with the amino acid solutions. Detection by exposure to iodine vapor. The detection limit was 0.18 µg for each enantiomer. For the best method performance the Cu(II)cation has to be involved.

      Classification: 38
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