Indian Drugs 44(10), 734 (2007). HPTLC of valdecoxib on silica gel with toluene - ethyl acetate 1:1. Quantitative evaluation by densitometry at 262 nm. Valdecoxib was well separated from rofecoxib. Linearity was between 800 and 1000 ng/zone. Recovery was 98.9 %.

Chromatographia 67 (1-2), 101-107 (2008). HPTLC of simvastatin and ezetimibe on silica gel with n-hexane – acetone 3:2. Quantification by densitometry in absorbance mode at 234 nm. The hRf value of simvastatin was 39 and of ezetimibe 50. Linearity was between 200 and 1600 ng/spot with correlation coefficients r2 = 0.9917 for simvastatin and r2 = 0.9927 for ezetimibe. Limits of detection and quantitation were 25 and 150 ng per band, respectively. For investigation of stability simvastatin and ezetimibe were subjected to acid, pH 6.8 phosphate buffer, oxidation, dry heat, and wet heat. The degradation products were well resolved from the pure drug, therefore the method could be effectively used for stability-indicating analysis.

59th Indian Pharmaceutical congress F-152, 426, (2007). HPTLC of rosiglitazone on silica gel aluminum layer with chloroform - ethyl acetate - ammonia 70:30:1. The hRf value of rosiglitazone was 40. Densitometric analysis in absorbance mode at 230 nm. Linearity was between 100 and 1000 ng/zone. Recovery (by standard addition method) was 99.6 %. Limit of detection and quantification was 10 ng and 50 ng/zone, respectively.

59th Indian Pharmaceutical congress F-224, 443, (2007). HPTLC of cilostazol on silica gel with ethyl acetate - toluene - methanol - ether 4:4:2:1. The hRf value was 64. Limit of detection and quantification was 7 ng/spot and 20 ng/spot respectively.

59th Indian Pharmaceutical Congress F-55, 402, (2007). HPTLC of metformin hydrochloride on silica gel with methanol - chloroform - ammonium acetate 6:3:1. Densitometry at 236 nm. The method has a range from 100 - 300 ng/zone. The limit of detection and quantification was 25 ng and 100 ng/zone, respectively. The method was applied for analysis of metformin hydrochloride in multi-component formulations containing glipizide, gliclazide and glibenclamide as well as in serum.

59th Indian Pharmaceutical congress F-225, 443, (2007). HPTLC cinnamaldehyde in the bark powder of Cinnamomum zeylenicum on silica gel with toluene - ethyl acetate - formic acid 190:10:1. Densitometric evaluation at 295 nm for quantification. The method was linear within the range of 31 and 157 ng/zone. The identity of the compound was confirmed by over overlaying the UV spectra of sample and standard. Cinnamomum bark was found to contain 0.25 % of cinnamaldehyde. Limit of detection and quantification was 3000 and 9900 ng/mL, respectively.

J. Chromatogr. A 1183 (1-2), 179-185 (2008). Ultrathin layer chromatography (UTLC) with a 10 µm thick monolithic silica sorbent layer provides fast separations with low limits of detection and reduced analyte and solvent volumes. Production of UTLC plates with controllable nanostructure and thickness. The separation characteristics of the layer depend on the nanostructure of the film. Layers made with in-plane anisotropic nanostructures exhibit a decoupling effect, where the analyte spots do not develop in the same direction as the solvent front moves. Discussion of the possibility of application in multi-dimensional TLC by added layer morphology and material selection.

Biochem. Biophys. Res. Commun. 365, 118-123 (2008). TLC of prenyl alcohols (farnesol and geranylgeraniol) after enzymatic hydrolysis of trans-isoprenyl diphosphates on RP-18 with acetone - water 9:1. Detection with iodine vapour. Quantitative determination by measuring the absolute radioactivity of the spots.