Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

Page
      101 014
      Diterpenoic acids analysis using a coupled TLC-surface-enhanced Raman spectroscopy system
      A. ORINÁK, I. TALIAN, E.V. EFREMOV, F. ARIESE, Renata ORIÁAKOVÁ (*Institute of Chemistry Sciences, Department of Physical Chemistry, University of P. J. Šafárik, Moyzesova 11, 041 54 Košice, Slovak Republic)

      Chromatographia 67 (3-4), 315-319 (2008). Presentation of a hyphenation technique of TLC with surface-based spectral methods which require a homogeneous surface for direct and quantitative analysis on the chromatographic plate after separation. Investigation of the suitability of two different chromatographic substrates and one interface for coupling surface-enhanced Raman spectroscopy (SERS) with TLC, since most chromatographic materials do not produce strong background signals in Raman spectroscopy. Evaluation of a chromatographic thin layer, specially produced for Raman spectroscopy measurements, a monolithic silica thin layer and a typical TLC plate with a modified aluminium backplate foil on one side used as an interface. Test analytes were three biologically active diterpenes (gibberellic acid, abietic acid, and kaurenoic acid) which were applied directly onto the surfaces, followed by the addition of silver colloid and measurements by SERS. The strongest signal (excitation at 514.5 nm) for gibberellic acid was obtained using a Raman treated thin layer where the enhancement factor value was determined to be 102, and several fundamental Raman bands for GA were found at 1622, 1593, 1570, 1542, 1366 and 1236 cm-1. However, no useful SERS signals were observed when the monolithic silica layer was used. Similar SERS spectra on modified aluminium backplate were obtained for abietic acid and gibberellic acid, but no SERS spectrum was obtained for kaurenoic acid.

      Classification: 4e
      101 045
      New rapid validated HPTLC method for the determination of galanthamine in Amaryllidaceae plant extracts
      A. ABOU-DONIA*, S. TOAIMA, H. HAMMODA, E. SHAWKY (*Department of Pharmacognosy, Faculty of Pharmacy, University of Alexandria, Alexandria 21521, Egypt, shawkyeman@yahoo.com)

      Phytochem. Anal. 19, 353-358 (2008). HPTLC of galanthamine in the bulbs of Narcissus cv. on silica gel with chloroform - methanol 9:1 with chamber saturation for 30 min. Quantitative determination by absorbance measurement at 288 nm. The hRf value was 72 and selectivity regarding matrix was given. Linearity was in the range of 0.25 and 7.5 µg/spot. The limits of detection and quantification were 47 and 142 ng/spot, respectively. Recovery was 97.8 %. No significant intra- and interday variation was observed. The method proved to be precise, accurate, and rapid in comparison with a reference HPLC method.

      Classification: 32e
      101 074
      High-performance thin-layer chromatographic method for quantification of atisine from Aconitum heterophyllum Roth
      R.K. PATEL*, A.M. PRAJAPATI, M.M. PATEL (*S. K. Patel College of Pharmaceutical Education and Research, Ganapat University, Kherava 382711, Mehsana, Gujarat, India)

      Indian Drugs 45 (3), 233-225 (2008). HPTLC of atisine in Aconitum heterophyllum on silica gel with toluene - ethyl acetate - diethylamine 7:2:1. Densitometric evaluation at 274 nm. Detection by spraying with Dragendorff reagent followed by spraying with 10 % sodium nitrate. Densitometric evaluation of reddish brown zones at 520 nm. Linearity of atisine was between 10 and 60 ng/spot.

      Classification: 32a
      101 098
      Silica thin-layer chromatographic studies of surfactants with mixed aqueous-organic eluents containing thiourea
      A. MOHAMMAD*, S.A. BHAWANI (*Analytical Research Laboratory, Department of Applied Chemistry, Faculty of Engineering & Technology, Aligarh Muslim University, Aligarh 202 002, India)

      J. Chromatogr. Sci. 46 (4), 298-303 (2008). HPTLC of three surfactants, cetyltrimethylammonium bromide (CTAB), dodecyltrimethylammonium bromide (DTAB), and polyoxyethylene (20) sorbitan monolaurate (Tween 20), on silica gel with 5 % aqueous thiourea - acetone - methanol 3:1:1. Evaluation of the effect of the carbon chain length of alcohols (methanol, ethanol, n-propanol, and n-butanol) on the mobility of these surfactants. The comparative study was performed with sulfur- (thiourea) and oxygen- (urea) containing compounds in the eluent. Investigation of the interference on the resolution of the mixture of CTAB, DTAB, and Tween 20, due to presence of metal cations as impurities.

      Classification: 35a
      102 025
      Quantitative TLC and gas chromatography determination of the lipid composition of raw and microwave roasted walnuts, hazelnuts, and almonds
      S. MOMCHILOVA, Boryana NIKOLOVA-DAMYANOVA* (*Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria; bmd@orgchm.bas.bg)

      J. Liq. Chromatogr. Relat. Technol. 30, 2267-2285 (2007). Analytical and preparative TLC of lipid classes, their fatty acid profiles, and the triacylglycerol and sterol composition on silica gel and modified silica gel (impregnated with silver nitrate for Ag-TLC or dimethyldichlorosilane for RP-TLC). TLC of lipid reference mixture on silica gel with hexane - acetone 25:4. Detection by spraying with 50 % ethanolic sulfuric acid and heating at 200 °C. Preparative TLC for isolation and quantification, followed by detection under UV light, spraying the edges with 2’,7’-dichlorofluorescein, scraping off, elution with diethyl ether and weighting. Quantitative Ag-TLC (impregnated by dipping into 0.5 % or 2 % methanolic solution of silver nitrate) followed by detection with bromine and sulfuryl chloride vapor for 30 min each, followed by heating at 180-200 °C. Preparative Ag-TLC with 4 different mobile phases. Quantitative RP-TLC on Kieselguhr treated for 6 h with vapors of dimethyldichlorosilane and washed with methanol using acetone - acetonitrile - water. Quantitative determination by absorbance measurement at 450 nm.

      Classification: 11c
      102 047
      Sildenafil determination in pharmaceutical products and aphrodisiac herbal preparations
      E.A. ABOURASHED (ElSohly Laboratories Inc., Oxford, MS 38655, USA, eabourashed@elsohly.com)

      CBS 99, 6-7 (2007). HPTLC of sildenafil in pharmaceutical products and herbal preparations (extracted with methanol) on silica gel with chloroform - methanol - diethylamine 90:10:1 in a twin-trough chamber saturated for 30 min. Quantitative determination by absorbance measurement at 305 nm. The hRf value of sildenafil was 48 and selectivity regarding matrix was given. The 4-level calibration (n=3) from 150 to 1200 ng/band showed a polynomial regression. Inter-day precision was <1 % (n=6). Mean recovery (by standard addition ) was 98.2 % for three different concentration levels.

      Classification: 17a
      102 067
      Lipophilicity of 5’-carbonates of lamivudine with antiretroviral activity
      S. RAVETTI, M. S. GUALDESI, Margarita Cristina BRINÓN* (*Departamento de Farmacia, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Ciudad Universitária, 5000 Córdoba, Argentina; macribri@fcg.unc.edu.ar)

      Correlation between different methods. J. Liq. Chromatogr. Relat. Technol. 31, 1014-1032 (2008). TLC of cytidine, lamivudine (2’,3’-dideoxy-3’-thiacytidine) and seven new 5’-carbonates of lamivudine on RP-18 with acetone - buffer pH 7.4 and methanol - buffer 7.4 mixtures with modifier contents between 40 and 80 % in 10 % increments. Detection under UV light. RP-TLC is a reliable and accurate technique to describe the lipophilic character of this nucleoside family of compounds.

      Classification: 21a
      102 092
      SIMULTANEOUS HPTLC ESTIMATION OF AMBROXOL HCl AND CETIRIZINE HCl IN THEIR COMBINED DOSE TABLET
      S. Bagade*, N. Gowekar, A. Kasture (*University Dept. of Pharmaceutical Sciences, R. T. M. Nagpur University Campus, Nagpur 440033, India, sbbagade@rediffmail.com)

      Asian J. Chem. 19(2), 1487-1493 (2007). TLC of ambroxol HCl and cetirizine HCl on silica gel with methanol - ethyl acetate - toluene - ammonia 3:10:12:1. Quantitative determination by absorbance measurement at 231 nm. The hRf value of ambroxol HCl was 78 and of cetirizine HCl 40. The calibration curve response was observed between 4 and 10 µg for ambroxol HCl and 0.4 and 0.8 µg for cetirizine HCl via peak height and area. The percent drug estimated for ambroxol HCl and cetirizine HCl from marketed formulation was 99.9, 100.2 by height and 100.8, 99.1 by area respectively. Recovery of ambroxol HCl via peak height and via peak area was 102.7 and 100.0 % respectively, and for cetirizine HCl 99.3 and 98.1 %.

      Classification: 32a
Page