Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

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      75 017
      Use of a macrocyclic antibiotic as the chiral selector for enantiomeric separations by TLC
      D.W. ARMSTRONG*, YIWEN ZHOU, (Univ. Missouri-Rolla, Dept. Chem., 341 Schrenk Hall, Rolla, Missouri 65401, USA)

      J. Liquid Chromatogr. 17, 1695-1707 (1994). Description of the use of vancomycin as chiral mobile phase additive for TLC resolution of 6-aminoquinolyl-N-hydroxy-succinimidyl carbamate derivatized amino acids, racemic drugs and dansyl-amino acids, giving excellent separation in the reversed-phase mode. Discussion of the influence of the nature of the stationary phase and the composition of the mobile phase on enantiomeric resolution.

      Keywords:
      Classification: 3d, 38
      80 166
      Planar chromatographic direct separation of some aromatic amino acids and aromatic amino alcohols into enantiomers using cyclodextrin mobile phase additives
      M. HUANG (Huang Mubin), H. LI (Li Hongkuan), G. LI (Li Gaolan), CH. YAN (Yan Changtai), L. WANG (Wang Liping), (Dept. Chem., Shandong Univ., Jinan 250100, P.R. China)

      J. Chromatogr. A 742, 289-294 (1996). TLC on cellulose with mobile phases containing cyclodextrin a or b. Investigation of the influence of the mobile phase composition and the structure of the compounds on enantiomeric resolution.

      Keywords:
      Classification: 18a, 38
      87 004
      Inclusion planar chromatography of enantiomeric and racemic compounds
      L. LEPRI, M. Del BUBBA, A. CINCINELLI, L. BODDI*, (Dept. of Public Health, Epidemiology and Env. Anal. Chem., Univ. of Florence, Via G. Capponi 9, 50121 Florence, Italy)

      J. Planar Chromatogr. 13, 384-387 (2000). TLC of enantiomers (1-acenaphthol, phenoxymethyl oxirane, 4-chlorophenoxymethyl oxirane, 2-methylphenoxymethyl oxirane, trityloxymethyl oxirane) on microcrystalline cellulose triacetate (MCTA) with 2-propanol - water resp. ethanol - water 4:1 or of 7 glycidyl ethers with mobile phases containing derivatized and underivatized cyclodextrins on chiral stationary phases. Detection under UV 254 and 366 nm. Quantitation by densitometry in reflectance mode at 254 nm.

      Keywords:
      Classification: 2c, 38
      96 167
      Some aspects of chiral separations in planar chromatography compared with HPLC
      A.M. SIOUFFI*, P. PIRAS, C. ROUSSEL (*Université Paul Cezanne, UMR 6180, 13397, Marseille, France)

      J. Planar Chromatogr. 18, 5-12 (2005). Review of the latest achievements in chiral separation by planar chromatography since 2001 (chiral ligand exchange; cellulose and derivatives; coated or impregnated layers; cyclodextrins; miscellaneous; diastereoisomers; conclusions). The emphasis is on cellulose derivatives and, especially, microcrystalline cellulose triacetate (MCTA) showing that TLC has some interesting features compared with HPLC. Some enantiomer separations have been successfully achieved by TLC whereas no data are available for HPLC. For tribenzoyl cellulose derivatives general trends for resoution by both TLC and HPLC are discussed. Furtheron reasons for the scarcity of publications on chiral separations by either planar chromatography or overpressured layer chromatography are discussed. The possibilities of PC for chiral separations are rather unexploited.

      Keywords: review
      Classification: 1, 38
      104 243
      Different approaches of impregnation for resolution of enantiomers of atenolol, propranolol and salbutamol using Cu(II)-l-amino acid complexes for ligand exchange on commercial thin-layer chromatographic plates
      R. BHUSHAN*, S. TANWAR (*Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee – 247667, India)

      J. Chromatogr. A 1217(8), 1396-1398 (2010). Sparation of enantiomers of atenolol, propranolol, and salbutamol using different loading/impregnation techniques for the Cu(II) complexes of l-proline, l-phenylalanine, l-histidine, N,N-dimethyl-l-phenylalanine, and l-tryptophan. TLC on silica gel with acetonitrile – methanol – 2 mM aqueous solution of Cu(II) 3:4:5. The different techniques were: A) using the Cu(II)-l-amino acid complex as chiral mobile phase additive, B) development of plates in solutions of Cu-complex, and C) with a solution of Cu(II)acetate as mobile phase additive for plates impregnated with the amino acids. Detection of zones by exposure to iodine vapor.

      Classification: 38
      115 052
      Thin-layer chromatographic investigation of L-cysteine in solution
      Agnieszka GODZIEK, Anna MACIEJOWSKA, Ewa TALIK, M. SAJEWICZ, Teresa KOWALSKA* (*Institute of Chemistry, University of Silesia, 9 Szklona Street, 40-006 Katowice, Poland, teresa.kowalska@us.edu.pl)

      J. Planar Chromatogr. 28, 144-151 (2015). TLC of L-cysteine on cellulose phase with 2-butanol - pyridine - glacial acetic acid - water 5:10:3:12. Just before development an equimolar amount of (1) manganese(II) acetate or (2) zinc(II) nitrate was added to the sample solutions. Detection in reflectance mode at 485 nm, concentration of L-cysteine and DL-cysteine in 70 % aqueous acetonitrile was 0.7 mg/mL. Developing distance was 7 cm, development time ca. 3 h. Derivatization by spraying with 0.5 % ninhydrin solution in 2-propanol, followed by heating for 5 min at 110 °C. The experiments demonstrate the spontaneous chiral conversion and spontaneous peptidization of L-cysteine, and the enantioseparation of L-cys and D-cys enantiomers is facilitated by chelating the transition metal cation (e.g. Mn(II)) with the cys ligands.

      Classification: 18a, 38
      63 207
      Separation and determination of some amino acid ester enantiomers by thin-layer chromatography after derivatization with (s)- (+)-naproxen
      N. BÜYÜKTIMKIN*, A. BUSCHANER, (Fac. Farm., Univ. Istanbul, 34452 Istanbul, Turkey)

      J. Chromatogr. 450, 281-283 (1988). TLC on silica with toluene - dichloromethane - tetrahydrofuran 5:1:1 or 5:1:2 in NH3 conditioned chamber. Detection by densitometry at 254 nm.

      Classification: 38
      68 218
      Chiral mobile phase additives in reversed-phase TLC
      J.D. DUNCAN, D.W. ARMSTRONG*, (*Univ. of Missouri-Rolla, Dept. Chem., Rolla, Missouri 65401, USA)

      J. Planar Chromatogr. 3, 65-67 (1990). Description of a method for chromatographic separation of enantiomers involving chiral mobile phase additives. Amino acid derivatives and several alkaloids are separated by TLC on different types of RP plates using a mobile phase containing maltosyl-ß-cyclodextrin. Visualization under 254 nm UV. A comparison was made between octadecyl, diphenyl, and ethyl RP TLC plates.

      Keywords:
      Classification: 18a, 22, 38