Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      100 118
      Development and validation of a High-Performance Thin-Layer Chromatographic method, with densitometry, for quantitative analysis of tizoxanide (a metabolite of nitazoxanide) in human plasma
      S. NAMUR*, L. CARINO, M. GONZALES-DE LA PARRA (*Fundación Liomont A. C. Mexico City, México, Privada Jesús del Monte 77, Cuajimalpa CP 05000, México)

      J. Planar Chromatogr. 20, 331-334 (2007). HPTLC of tizoxanide (with nitazoxanide as internal standard) on silica gel prewashed with methanol in a twin-trough chamber with toluene - ethyl acetate - acetic acid 62:134:4. UV detection and quantitation at 313 nm for the internal standard and at 410 nm for tizoxanide.

      Classification: 32a
      100 153
      Validation and development of an HPTLC method for the simultaneous estimation of olmesartan medoxomil and hydrochlorothiazide in tablet dosage form
      S.H. SHAH*, C.R. SHAH, N.J. SHAH, N.M. PATEL, B.N. SUHAGIA, (*Shri B.M. Shah College of Pharm. Edu. and Res. Gujrat, India)

      59th Indian Pharmaceutical congress F-10, 392, (2007). HPTLC of olmesartan medoxomil and hydrochlorothiazide on silica gel with acetonitrile - chloroform - glacial acetic acid 14:4:1 with chamber saturation for 30 min. Densitometric evaluation at 254 nm. Linearity was between 480 and 900 ng/zone for olmesartan and 150 and 600 ng/zone for hydrochlorothiazide. Recovery was 99.7 - 100.4 % . The method can be used for routine quality control of formulations.

      Classification: 32a
      101 065
      Optimization of UDP-N-acetylmuramic acid synthesis
      J. HUMLJAN*, S. STARCEVIC, V. CAR, P. STEFANIC ANDERLUH, D. KOCJAN, B. JENKO, U. URLEB (*Drug Discovery Department, Lek Pharmaceuticals, Verovskova 57, 1526 Ljubljana, Slovenia; jan.humljan@sandoz.com)

      Pharmazie 63, 102-106 (2008). TLC of benzyl 2-acetamido-6-O-acetyl-3-O-[(R)-1-carboxyethyl]-2-deoxy-alpha-D-glucopyranoside 1’,4-lactone, 2-acetamido-6-O-acetyl-3-O-[(R)-1-carboxyethyl]-2-deoxy-alpha-D-glucopyranoside 1’,4-lactone, and 2-acetamido-6-O-acetyl-3-O-[(R)-1-carboxyethyl]-2-deoxy-alpha-D-glucopyranoside-1-alpha-(diphenyl phosphate) 1’,4-lactone on silica gel with ethyl acetate - acetone 2:1. TLC of triethylammonium muramyl phosphate on silica gel with isopropanol - water - 25 % ammonia 6:1:3. Evaluation under UV light and by heating the plate at 250 °C.

      Classification: 32a
      102 096
      High performance thin layer chromatographic method for simultaneous estimation of ibuprofen and pseudoephedrine hydrochloride
      S. Chitlange*, D. Sakarkar, S. Wankhede and S. Wadodkar (*Pad. Dr. D. Y. Patil Institute of Pharmaceutical Science and Research, S. T. Nagar, Pimpri, Pune 411018, India)

      Ind. J. Pharm. Sci. 70(3), 398 - 400 (2008). HPTLC of ibuprofen and pseudoephedrine HCl on silica gel with tert-butanol - ethyl acetate - acetic acid - water 7:4:2:2. Quantitative determination by absorbance measurement at 254 nm. The hRf value of pseudoephedrine was 68 and of ibuprofen 91. The method was linear in the concentration range of 45.6 - 75.6 µg/mL for ibuprofen and 6.8 - 11.3 µg/mL for pseudoephedrine. The recovery was between 100.7 and 101.0 % for both compounds. The method was suitable for routine quality control.

      Classification: 32a
      102 119
      Use of HPTLC as a problem solving technique in pharmaceutical analysis
      Clare MCKINLAY (Analytical Sciences, GlaxoSmithKline, Medicines Research Park, Gunnels Wood Road, Stevenage, Hertfordshire, UK, SG 1 1WZ, clare@mckinlay@gsk.com)

      CBS 101, 12-13 (2008). During a drug substance stability study a mass imbalance was discovered in light degraded samples. HPTLC on silica gel first with ethyl acetate - heptane, then, after drying, with tetrahydrofuran in a horizontal developing chamber. Detection under UV 254 nm and by densitometry at 240 nm. During another project differences in color between batches of a drug substance were observed. HPTLC on amino phase with methanol in a horizontal developing chamber. Detection under white light and under UV 366/>400 nm.

      Classification: 32a
      102 140
      Use of video densitometry and scanning densitometry to study an impact of silica gel and L-arginine on the retention of ibuprofen and naproxen in TLC systems
      M. SAJEWICZ, M. GONTARSKA, A. DABROWA, Teresa KOWALSKA* (*Institute of Chemistry, Silesian University, 9, Szkolna Street, 40-006 Katowice, Poland; kowalska@us.edu.pl)

      J. Liq. Chromatogr. Relat. Technol. 30, 2369-2383 (2007). TLC of 2-arylpropionic acids, namely ibuprofen and naproxen, on silica gel and silica gel impregnated with a 0.03 mol/L solution of L-arginine in methanol by dipping for 2 s, with ethanol and ethanol containing several drops of acetic acid. Quantitative determination by absorbance measurement at 254 nm. It was demonstrated that the crystalline chirality of the silica gel adsorbent is most probably responsible for the horizontal enantioseparation, whereas the molecular chirality of L-arginine deposited on the silica gel layer is responsible for the vertical enantioseparation.

      Classification: 32a
      102 160
      A validated HPTLC method for simultaneous estimation of lamivudine and zidovudine in tablets
      S. WANKHEDE*, K. GUPTA, M. TAJNE, S. WADODKAR (*Dept. of Pharmaceutical Science, Nagpur Univeristy Campus, Amravati Rd., Nagpur 440033, India, sagar_277@rediffmail.com)

      Asian J. Chem. 18(4), 2669-2672 (2006). TLC of lamivudine and zidovudine on silica gel with toluene - methanol - n-hexane 14:3:2. Quantitative determination by absorbance measurement at 275 nm. Linearity for lamivudine and zidovudine was in the range of 0.8-2.0 and 1.5-4.0 µg/zone, respectively. The average recovery was 99.4 - 100.3 % for both drugs. The method can be applied for routine simultaneous estimation in combined dosage form.

      Classification: 32a
      103 122
      Thin-layer and column-chromatographic methods for simultaneous analysis of ambroxol hydrochloride and doxycycline hyclate in a binary mixture
      M.A.A. MOHAMMAD*, N.H. ZAWILLA (*Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini 11562, Cairo, Egypt; mohammadazim97@yahoo.com)

      J. Planar Chromatogr. 22, 201-206 (2009). TLC of ambroxol hydrochloride and doxycycline hyclate on silica gel with ethyl acetate - ethanol - glacial acetic acid - water 90:40:5:10 with chamber saturation for 1 h. Detection under UV 254 nm. Quantitative determination by absorbance measurement at 254 nm for ambroxol hydrochloride and 270 nm for doxycycline hyclate.

      Classification: 32a