Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      100 082
      TLC of quaternary pyridinium aldoximes, antidotes of organophosphorus esterase inhibitors
      T. CSERMELY, G. PETROIANU, K. KUCA, J. FÜRÉSZ, F. DARVAS, Z. GULYÁS, R. LAUFER, Huba KALÁSZ* (*Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Nagyvárad tér 4, Hungary; huba.kalasz@gmail.com)

      J. Planar Chromatogr. 20, 39-42 (2007). Displacement TLC of quaternary pyridinium aldoximes (e. g. pralidoxime and obidoxime) on silica gel impregnated with paraffin oil by continous development with 10 % paraffin oil in n-hexane for 18 h with water - acetone - hydrochloric acid 8:1:1. Detection under UV light at 254 nm.

      Classification: 32a
      100 119
      A new validated HPTLC method for the quantitative estimation of atorvastatin calcium and amlodipine besylate in tablets
      M.G. PAI, R. GUDE*, S. BHENDE, D. VERLEKAR (*Goa College of Pharmacy, Panaji, Goa, India)

      59th Indian Pharmaceutical congress F-154, 426, 2007. HPTLC of atorvastatin calcium and amlodipine besylate on silica gel with ethyl acetate - 1,4-dioxane - methanol - ammonia 10:1:2:1. Quantitative evaluation by densitometry at 254 nm. The hRf value was 35 and 56 for atorvastatin and amlodipine, respectively. Linearity was between 200 and 1000 ng/zone for atorvastatin and 400 and 2000 ng/zone for amlodipine. Recovery was 99.8 - 100.9 % for both compounds. The method was found suitable for routine quality control of formulations containing both drugs in combined formulations.

      Classification: 32a
      100 155
      Simultaneous assay of olanzapine and fluoxetine in tablets by column High-Performance Liquid Chromatography and High-Performance Thin-Layer Chromatography
      C.R. SHAH*, N.J. SHAH, B.N. SUHAGIA, N.M. PATEL (* Shri B. M. Shah College of Pharmaceutical Education and Research, Department of Pharmaceutical Chemistry, College Campus, Modasa-383315, Gujarat, India; crshah681@yahoo.com)

      J. AOAC Int. 90, 1573-1578 (2007). TLC of olanzapine [2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine] and fluoxetine [(+/-)-N-methyl-3-phenyl-3-[(alpha,alpha,alpha-trifluoro-p-tolyl)oxy]propylamine] on silica gel using methanol - toluene 2:1 in a twin-trough chamber with chamber saturation. Quantitation by densitometry in absorption mode at 233 nm.

      Classification: 32a
      101 070
      HPTLC-densitometric analysis of candesartan cilexetil and hydrochlorothiazide in tablets
      B.H. MEHTA, S.B. MORGE* (*Department of Chemistry, University of Mumbai, Vidaynagari, Santacruz [E] Mumbai 400098, India; s_morge@yahoo.com)

      J. Planar Chromatogr. 21, 173-176 (2008). HPTLC of candesartan cilexetil and hydrochlorothiazide on silica gel with acetone - chloroform - ethyl acetate - methanol 6:6:6:1 at 25 +/- 5°C and a relative humidity of 50-60 % in a saturated twin trough separation chamber. Quantitation by densitometry at 280 nm.

      Classification: 32a
      102 097
      Lipophilicity determination of some ACE inhibitors by TLC
      T. CSERMELY, H. KALÁSZ*, K. DEÁK, M. Y. HASAN, F. DARVAS, G. PETROIANU (*Department of Pharmacology and Therapeutics, United Arab Emirates University, Al Ain, P.O. Box 17666, United Arab Emirates; huba.kalasz@gmail.com)

      J. Liq. Chromatogr. Relat. Technol. 31, 2019-2034 (2008). TLC of captopril, delapril, enalapril, lisinopril, amd moexipril on silica gel (impregnated by continous development with 10 % paraffin oil in n-hexane for 18 h) and RP-18 with various mobile phases. Detection under UV 254 nm. TLC is a fast and economical method for the determination of lipophilicity.

      Classification: 32a
      102 121
      Validated HPTLC method and content uniformity test for analysis of telmisartan and hydrochlorothiazide in tablet dosage forms
      S. Mogre*, B. Mehta (*Dept. of Chemistry, University of Mumbai, Vidyanagari, Santacruz (E) Mumbai 400098, India)

      J. Pharm. Res. 7(2), 126-128 (2008). HPTLC on silica gel with acetone - chloroform - ethyl acetate - methanol 6:6:6:1. Quantitative determination by absorbance measurement at 280 nm. The hRf value for telmisartan was 27 and for hydrochlorothiazide 45. The regression curve shows good linear relationship in the concentration range of 25.5 - 128.0 µg for hydrochlorothiazide and 81.6 - 408.0 µg for telmisartan. The content uniformity test was carried out as per the USP specification of the content uniformity test. The percent drug estimated from the marketed formulations were found to be in the range 99.3 and 100.5 for both drugs. The percent recoveries of drug carried out by the standard addition method was found to be 100.3 and 99.4 for hydrochlorothiazide and telmisartan respectively. The proposed method was found suitable for routine quality control and content uniformity tests.

      Classification: 32a
      102 142
      Development of stability-indicating HPTLC method for the determination of trandolapril in bulk drug and pharmaceutical dosage form
      V.L. SATHIYANARAYANAN*, A. KHEDKAR, J. RAO, S. YADAV (*Poona College of Pharmacy, Bharati Vidyapeeth, Pune, India)

      60th Indian Pharmaceutical Congress PA-195, (2008). HPTLC of trandolapril on silica gel with toluene - ethyl acetate - methanol - formic acid 5:16:2:1. The hRf value of trandolapril was 51. Trandolapril was subjected to different stress conditions like acidic and alkaline hydrolysis, oxidation, dry heat, wet heat, neutral condition and photodegradation. The degradation products were well resolved from the pure drug. Quantitative determination by absorbance measurement at 220 nm. Linearity was between 300-1800 ng/spot. The method was suitable for routine analysis of the drug in bulk and pharmaceutical dosage form.

      Classification: 32a
      103 082
      HPTLC analysis of a new ultra-short-acting thiazolodiazepine hypnotic (HIE-124) in spiked human plasma
      E.A. ABOURASHED*, M.M. HEFNAWY, H.I. EL-SUBBAGH (*ElSohly Laboratories, 5 Industrial Park Drive, Oxford, MS 38655, USA; eabourashed@elsohly.com)

      J. Planar Chromatogr. 22, 183-186 (2009). HPTLC of ethyl 8-oxo-5,6,7,8-tetrahydrothiazolo[3,2-a][1,3]diazepin-3-carboxylate (HIE-124) in plasma (with diazepam as internal standard) on silica gel with chloroform - ethyl acetate 4:1 with chamber saturation for 30 min. Quantitative determination by absorbance measurement at 265 nm. The limit of detection and quantification was 20 µg/L (40 ng/band) and 40 µg/L (80 ng/band), respectively.

      Classification: 32a