Indian Drugs 42 (9), 600-603 (2005). HPTLC of cinnarizine and domperidone in tablets, on silica gel with toluene - ethyl acetate - methanol 14:1:5. Quantitative determination by absorbance measurement at 271 nm. Rf values of cinnarizine was 0.85 and of domperidone 0.4. Linearity was observed in the range of 0.1-0.4 for cinnarizine and 0.075-0.3 µg/µL for domperidone. The recoveries were in the range of 98.95-100.25 %. The tablet matrix did not interfere with the assay.

J. Planar Chromatogr. 19, 422-426 (2006). TLC of 26 substituted anilides of pyrazine-2-carboxylic acids on silica gel impregnated with a solution of silicone oil in diethyl ether 19:1 for 16 h. The aqueous component of the mobile phases was 0.05 M phosphate buffer of pH 7.4 or 3.0; methanol was used as organic modifier; separation in a pre-saturated chamber. Detection under UV light at 254 nm. .

Indian Drugs 44 (2), 111-116 (2007). HPTLC for simultaneous determination of mosapride citrate and pantoprazole from pharmaceutical formulations by using loratadine as an internal standard. HPTLC on silica gel with toluene - acetone - methanol 16:4:1. Quantitative determination by absorbance measurement at 254 nm. Mosapride citrate response was linear over the range 0.075 - 0.225 µg/mL, and that for pantoprazole was 0.2 - 0.6 µg/mL. Recovery was 99.6 - 101.3 % for both compounds. The developed method was validated regarding accuracy, precision, and stability, and can be used for routine quality control of formulations containing mosapride citrate and pantoprazole.

Indian J. Pharm. Sci. 68 (6),788-789 (2007). HPTLC of etorocoxib in dosage forms on silica gel with chloroform - methanol - toulene 2:1:2. The plate was scanned at 289 nm for quantitative evaluation. The hRf value of etorocoxib was 58. The method was linear in the range of 100 - 600 ng/spot.The method was validated for accuracy, precision and repeatability. It was found suitable for routine quality control of formulations.

J. Liq. Chromatogr. Relat. Technol. 29, 2059-2069 (2006). TLC of S-(+)-ibuprofen, S-(+)-naproxen, and R,S-(+/-)-2-phenylpropionic acid on silica gel (prewashed with methanol - water 9:1 and impregnated with a 0.03 mol/L solution of L-arginine in methanol by dipping for 2 s at 22 +/- 2 °C) with acetonitrile - methanol - water 10:2:3 for naproxen and 20:4:3 for 2-phenylpropionic acid. Both mobile phases contained several drops of acetic acid to fix the pH at 4.8. Densitometric evaluation at 210 nm.

J. Planar Chromatogr. 20, 457-461 (2007). HPTLC of rivastigmine ((-)-S-N-ethyl-3-[(1-dimethylamino)ethyl]-N-methylphenylcarbamate) and impurity on silica gel with chloroform - methanol 2:3 in a twin-trough chamber with chamber saturation for 30 min. Densitometric analysis was performed in absorbance mode at 210 nm. Limits of detection were 30 and 100 ng/zone, respectively.

CBS 98, 2-4 (2007). HPTLC of amino-3-propan-1-ol, a degradation product of dexpanthenol, on silica gel with ethanol - water - acetic acid 16:3:1. To the mobile phase the derivatization reagent was added, i.e. 0.5 g ninhydrin were dissolved in 100 mL solvent mixture. Development in the horizontal developing chamber from both plate sides over 40 mm. Detection by heating at 105 °C for 5 min. Quantitative determination by absorbance measurement at 486 nm. The hRf value of amino-propanol was 50. The mean repeatability was 4.9 % at 5 different concentration levels. The relative standard deviation of the intermediate precision (n=9) was 5.7 %. The limit of detection and quantification was 4.5 µg/mL and 15 µg/mL, respectively (related to the application volume of 2 µL). Recovery (n=15) was 102 %.

J. Planar Chromatogr. 20, 145-147 (2007). HPTLC of clotrimazole and tinidazole on silica gel in a twin-trough chamber with toluene - ethyl acetate - methanol - glacial acetic acid 60:30:10:3 with chamber saturation for 10 min. Quantitation by scanning at 254 nm.