Abstract G-9, IPC (2005). HPTLC of pantoprazole and mosapride in combined dosage form on silica gel with methanol - toluene - chloroform 4:30:15. Quantitative determination by absorbance measurement at 305 nm. The hRf value of pantoprazole was 31 and of mosapride 43, recovery was 99.9-101.1 %. Accuracy, precision, and linearity of the method were established.

J. Planar Chromatogr. 18, 384-387 (2005). TLC of thirty-seven N-[(4-arylpiperazin-1-yl)alkyl]-2-azaspiro[4.4]nonane- and [4.5]decane-1,3-dione derivatives on RP-18 in a pre-saturated chamber with n-propanol - Tris buffer (pH 7.0) mixtures. Detection under UV at 254 nm.

Part 1. Lipophilicity of 8-aryl-3-phenyl-6,7-dihydro-4H-imidazo[2,1-c][1,2,4]triazin-4-ones. J. Planar Chromatogr. 18, 274-281 (2005). Determination of the lipophilicity of 13 carbonyl derivatives of imidazo[1,2-c][1,2,4]triazine by TLC on RP-18 and RP-18 W in horizontal chambers with aqueous mobile phases containing organic modifiers (methanol or dioxane). Detection under UV light at 254 and 366 nm.

Abstract GP-41, IPC (2005). HPTLC of tizanidine in tablets on silica gel with ethyl acetate - methanol - acetic acid 60:4:1. Linearity range was 0.5-0.6 µg, LOQ 0.5 µg, and average recovery was 99.4-101.6 %. The method was validated according to ICH guidelines.

Indian Drugs 42 (10), 665-670 (2005). HPTLC of carbamazepine, phenytoin, and phenobarbitone extracted with ethyl acetate from human serum, on silica gel with toluene - acetone 5:2. Quantification by absorbance measurement at 217 nm. Rf values were 0.20 for carbamazepine, 0.41 for phenytoin, and 0.49 for phenobarbitone. The linearity (r=0.998) was in the range of 100-2000 ng. LOQ was found to be 30 ng/spot for carbamazepine and 80 ng/spot for phenytoin and phenobarbitone. The accuracy was in the range of 88.5 to 98.1 % and the CV in range of 1.1 to 3.9 %. Intra day and inter day reproducibility was comparable and within the stated limits.

Acta Chrom. 11, 96-101 (2001). HPTLC of the muscle relaxant carisoprodol on silica gel uniplates with inorganic binder and fluorescent indicator, prewashed with dichloromethane – methanol 1:1, with chloroform – acetone 4:1 as mobile phase. Detection by spraying with conc. sulfuric acid – methanol 1:1 followed by heating at 150 ºC for 5 min. Quantitative determination by absorbance measurement at 550 nm. The method was applied to tablets containing carisoprodol as the only active ingredient and to tablets containing carisoprodol with aspirin and with aspirin plus codeine phosphate.

Acta Chrom. 16, 153-163 (2006). HPTLC of salicylamide in diuretic tablets and pain-relief tablets on silica gel with concentrating zones (pre-washed with dichloromethane - acetone 1:1) with dichloromethane – acetone 4:1. Quantification by densitometry at 254 nm. The method is suitable for routine quality-control analysis of pharmaceuticals containing salicylamide.

Ind. J. Pharm. Sci. 68 (6), 838-840 (2006). HPTLC of ofloxacin and ornidazole in tablet dosage form on silica gel with n-butanol - ethanol - ammonia 5:5:4. Quantitative determination by absorbance measurement at 295 nm. The method was found to be linear in the concentrate range of 1-5 ng/spot with recovery of 99.5-102.5 % for both compounds. The method was validated for linearity, accuracy, precision, repeatability, and specificity.