Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      95 066
      TLC analysis of non-steroidal anti-inflammatory drugs and videodensitometric determination of fenbufen in tablets
      H. HOPKALA, A. POMYKALSKI* (*Department of Medicinal Chemistry, Faculty of Pharmacy, Prof. Skubiszewski Medical Universit y of Lublin, 6 Chodzki St., 20-093 Lublin, Poland)

      J. Planar Chromatogr. 17, 383-387 (2004). TLC of fenbufen, ibuprofen, ketoprofen, diclofenac sodium, mefenamic acid, and tiaprofenic acid on silica gel by ascending and horizontal techniques, and on RP-18 in horizontal chambers. Good separation was achieved on silica gel by horizontal development with chloroform - methanol - 25 % ammonia 67:25:8; reversed phase chromatography on RP-18 with 0.15 mol/L phosphate buffer, pH 5.73 - 10 % CTMA-Br (N-cetyl-N,N,N-trimethylammonium bromide) in methanol 7:13 enabled better separation of the six drugs. Detection under UV light at 254 nm - for ibuprofen detection was best achieved after normal phase chromatography with 20 % aqueous sodium carbonate solution. A simple videodensitometric procedure was developed and validated. RSD for quantitation of fenbufen was 2.44 - 3.10 %.

      Classification: 32a
      95 090
      HPTLC method for the simultaneous estimation of valdecoxib and tizanidine hydrochloride in tablets
      A. SUGANTHI VIPIN PRAKASH*, Sapna SHRIKUMAR, K. A. Mirkasim, T. K. RAVI (*College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences, Coimbatore 641 044, India)

      IPC 56th 2004, Abstract No. GP-3. Simultaneous HPTLC determination of valdecoxib and tizanidine in tablets on silica gel with n-butyl acetate - formic acid - chloroform 7:3:2. Quantitative determination by densitometric scanning at 283 nm. The Rf values of valdecoxib and tizanidine were 0.78 and 0.39 respectively. Linearity range was 200 - 1000 ng/spot and 60 - 300 ng/spot respectively. Mean recovery for both of the compounds was 99.57 – 101.28 %. The method was validated for accuracy, precision, linearity, LOD, and LOQ.

      Classification: 32a
      96 092
      Quantitative analysis of repaglinide in tablets by reversed-phase thin-layer chromatography with densitometric UV detection
      Anna Gumieniczek*, A. Berecka, H. Hopkala (*Department of Medicinal Chemistry, Medical University of Lublin, Chodzki Str. 6, 20-093 Lublin, Poland)

      J. Planar Chromatogr. 18, 155-159 (2005). TLC of repaglinide on RP-8 with acetonitrile - phosphate buffer pH 6.0 3:2. Quantitative determination by absorbance measurement at 225 nm. Calibration in the range of 0.6-3.6 µg was linear with a good correlation coefficient (r = 0.998 +/- 0.001). Limits of quantitation and detection were 0.27 µg and 0.08 µg, respectively.

      Classification: 32a
      96 122
      Determination of bezafibrate and ciprofibrate in pharmaceutical formulations by densitometric and videodensitometric TLC
      Genowefa Misztal*, L. Komsta (*Department of Medicinal Chemistry, Medical University, 6 Chodzki, 20-093 Lublin, Poland)

      J. Planar Chromatogr. 18, 188-193 (2005). HPTLC of of bezafibrate and ciprofibrate in tablets and capsules on diol phases with hexane - tetrahydrofuran 4:1. Quantitative determination by absorbance measurement at 227 nm and videoscanning at 254 nm. Recovery measured by use of densitometry was 100.3 % (RSD 7.8 %) for bezafibrate and 98.0 % (RSD 6.1 %) for ciprofibrate. Videodensitometry resulted in recovery of 96.2 % (RSD 9.8 %) and 97.8 % (RSD 11.2 %), respectively.

      Classification: 32a
      96 145
      Rapid identificaton and quantification of chlorpheniramine maleate or pheniramine maleate in pharmaceutical preparations by thin-layer chromatography-densitometry
      S.P. SUBRAMANIYAN, S.K. DAS* (*Government of India, Department of Biochemistry, Central Drugs Laboratory, 3, Kyd St, Kolkata 700 016, India)

      J. AOAC Int. 87, 1319-1322 (2004). TLC of chlorpheniramine and pheniramine maleate in combination with other drugs in pharmaceutical preparations of tablets, syrups, eye and ear drops etc. on silica gel with cyclohexane - chloroform - methanol - diethylamine 9:8:1:2. Detection under UV light at 254 nm and quantitative determination by scanning at 260 nm. Recoveries of CPM and PM were 100.1 +/- 0.8 % and 100.1 +/- 0.9 %, respectively.

      Classification: 32a
      97 086
      Development of HPTLC Method for simultaneous estimation of captopril and hydrochlorothiazide in combined dosage form
      S. G. WALODE*, M.S. CHARDE, M.R. TAJNE, A.V.KASTURE (*Dept. of Pharm. Sciences, Nagpur University Campus, Amravati Road, Nagpur 440033, India)

      Indian Drugs 42 (6), 340-344 (2005). HPTLC of captopril and hydrochlorothiazide in tablets on silica gel with methanol - toluene - ethyl acetate - glacial acetic acid 2:12:6:1. Quantitative determination by absorbance measurement at 219 nm. The Rf value of hydrochlorothiazide was 0.38 and of captopril 0.57. The calibration curve response was 4-14 µg for both drugs. Recovery was determined by standard addition method. The percent recovery by area was found to be 100.25 for captopril and 99.98 for hydrochlorothiazide. The method was suitable for routine quality control of such formulations.

      Classification: 32a
      97 130
      Preliminary phytochemical investigation and antimicrobial activity of fruits of Mimusops elengi Linn
      S. MUNDHADA*, P. TATKE (*C.U.Shah College of Pharmacy, SNDT Women’s University, Juhu Campus, Santacruz (W), Mumbai 400049, India)

      TLC/HPTLC fingerprint profile. Indian Drugs 42 (7), 417-423 (2005). Unripe, powdered fruits of Mimusops elengi Linn. extracted individually and successively with acetone and methanol were evaluated for antimicrobial activity. HPTLC on silica gel with toluene - ethyl acetate - chloroform - acetic acid 35:35:28:2. Detection under UV 254 nm, 366 nm and after spraying with anisaldehyde sulphuric acid reagent for qualitative evaluation for different phyto constituents.

      Classification: 32a
      98 071
      Estimation of impurity profiles of drugs and related materials
      G. BALOGH, E. CSIZÉR, G. G. FERENCZY, Z. HALMOS, B. HERÉNYI, P. HORVATH, A. LAUKÓ, S. GÖRÖG* (*Chemical Works of Gedeon Richter Ltd. , P. O. B. 27, H-1475, Budapest, Hungary)

      12. Isolation and identification of an isomeric impurity in danazol. Pharm. Research 12, 295-298 (1995). TLC of isodanazol according to The United States Pharmacopoeia XXII, 1990, pp. 379-380 and K. Ferenczi-Fodor, Z. Végh, Z. Pap-Sziklay, J. Planar chromatogr. 6, 198-203 (1993). Ferenczi-Fodor described a validated method for the selective determination of three individual impurities in danazol based on TLC-densitometric measurement at 252 nm. The Rf values of danazol and isodanazol in the TLC systems of USP XXII are 0.29 and 0.33, respectively, while in the system of Ferenczi-Fodor et al. 0.47 and 0.58.

      Classification: 32a