Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      98 076
      Validated HPLC and HPTLC stability-indicated methods for determination of alfuzosin hydrochloride in bulk powder and pharmaceutical formulations
      A. FAYED*, M. SHEHATA, N. HASSAN, S. EL-WESHAHY (*Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt, fayedaeg@yahoo.com)

      J. Sep. Sci. 29, 2716-2724 (2006). HPTLC of alfuzosin hydrochloride subjected to stress conditions (alkaline, acidic, oxidative, thermal, and photo-degradation) on silica gel with methanol - ammonia 125:3. Quantitative determination by absorbance measurement at 245 nm. Linearity of determination of alfuzosin is between 0.5 and 7.0 µg and its average percentage recovery is 98.5 - 101.8 %. The drug is well separated from its degradation products upon applying the two methods.

      Classification: 32a
      98 108
      Determination of gatifloxacin and ornidazole in tablet dosage forms by high-performance thin-layer chromatography
      B. SUHAGIA, S. SHAH, I. RATHOD, H. PATEL*, D. SHAH, B. MAROLIA (*Department of Quality Assurance, L.M. College of Pharmacy, Gujarat, India, patelhary2001@yahoo.com)

      Anal. Sci. 22, 743-745 (2006). HPTLC of gatifloxacin and ornidazole on silica gel with n-butanol – methanol 8:1 and 1 drop ammonia with chamber saturation for 45 min. Quantitative determination by absorbance measurement at 302 nm. Linearity of determination of gatifloxacin is 100 – 500 ng and of ornidazole 250 – 1250 ng, with a correlation coefficient of more than 0.9850. The intra-day and inter-day coefficients of variation are found to be in the range of 0.68 - 2.58 % and 0.37 - 3.62%, respectively.

      Classification: 32a
      99 100
      Development and validation of a HPTLC method for the simultaneous estimation of atorvastatin calcium and ezetimibe
      B. G. CHAUDHARI*, N. M. PATEL, P. B. SHAH, K. P. MODI (*Shri B. M. Shah College of Pharmacy, Modasa 383315, Shri B. M. Shah College of Pharmaceutical Education & Research , Modasa 383315, India)

      Indian J. Pharm. Sci. 68 (6), 793-796 (2006). HPTLC of atorvastatin calcium and ezetimibe in combined dosage form on silica gel with chloroform - benzene - methanol - acetic acid 60:30:10:1. Detection under UV 250 nm.The method was validated in terms of linearity, accuracy, precision and specificity.The calibration curve was found to be linear between 0.8 and 4.0 µg/spot for atorvastatin calcium and 0.1 and 1.0 µg/spot for ezetimibe. The limit of detection and the limit of quantification for atorvastation calcium were found to be 170 ng/spot and 570 ng/spot, respectively, and for ezetimibe 20 ng/spot and 70 ng/spot, respectively.The recovery was in the range of 99.9 - 102.7 %.

      Classification: 32a
      99 133
      Investigations on the thermal behavior of omeprazole and other sulfoxides
      K. M. ROSENBLATT, H. BUNJES, A, SEELING, H, OELSCHLAEGER* (*Institute of Pharmacy, Philosophenweg 13, D-07743 Jena, Germany)

      Pharmazie 60, 503-507 (2005). TLC of omeprazole (5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole) and more than 30 degradation products on silica gel with ethyl acetate. Evaluation in white light and under UV 254 and 366 nm.

      Classification: 32a
      100 079
      Separation and Determination of Nitroguanidine and Guanidine Nitrate by HPTLC
      M. CHALOOSI*, M. AMOLI-DIVA, F. GHOLAMIAN, S. MOZAFFARI (*Faculty of Chemistry, Tarbiat Moalem University, 49 Mofateh Avenue, Tehran, Iran)

      Chromatographia 66 (3-4), 295-296 (2007). HPLC of nitroguanidine and guanidine nitrate on silica gel layers with dioxane – tetrahydrofuran 1:1. Detection under UV 210 nm for guanidine nitrate and 265 nm for nitroguanidine. Quantification by absorbance densitometry using peak area calibration. The method was used for separation and quantification of the compounds for online and off-line quality control of synthesis.

      Classification: 32a
      100 118
      Development and validation of a High-Performance Thin-Layer Chromatographic method, with densitometry, for quantitative analysis of tizoxanide (a metabolite of nitazoxanide) in human plasma
      S. NAMUR*, L. CARINO, M. GONZALES-DE LA PARRA (*Fundación Liomont A. C. Mexico City, México, Privada Jesús del Monte 77, Cuajimalpa CP 05000, México)

      J. Planar Chromatogr. 20, 331-334 (2007). HPTLC of tizoxanide (with nitazoxanide as internal standard) on silica gel prewashed with methanol in a twin-trough chamber with toluene - ethyl acetate - acetic acid 62:134:4. UV detection and quantitation at 313 nm for the internal standard and at 410 nm for tizoxanide.

      Classification: 32a
      100 153
      Validation and development of an HPTLC method for the simultaneous estimation of olmesartan medoxomil and hydrochlorothiazide in tablet dosage form
      S.H. SHAH*, C.R. SHAH, N.J. SHAH, N.M. PATEL, B.N. SUHAGIA, (*Shri B.M. Shah College of Pharm. Edu. and Res. Gujrat, India)

      59th Indian Pharmaceutical congress F-10, 392, (2007). HPTLC of olmesartan medoxomil and hydrochlorothiazide on silica gel with acetonitrile - chloroform - glacial acetic acid 14:4:1 with chamber saturation for 30 min. Densitometric evaluation at 254 nm. Linearity was between 480 and 900 ng/zone for olmesartan and 150 and 600 ng/zone for hydrochlorothiazide. Recovery was 99.7 - 100.4 % . The method can be used for routine quality control of formulations.

      Classification: 32a
      101 065
      Optimization of UDP-N-acetylmuramic acid synthesis
      J. HUMLJAN*, S. STARCEVIC, V. CAR, P. STEFANIC ANDERLUH, D. KOCJAN, B. JENKO, U. URLEB (*Drug Discovery Department, Lek Pharmaceuticals, Verovskova 57, 1526 Ljubljana, Slovenia; jan.humljan@sandoz.com)

      Pharmazie 63, 102-106 (2008). TLC of benzyl 2-acetamido-6-O-acetyl-3-O-[(R)-1-carboxyethyl]-2-deoxy-alpha-D-glucopyranoside 1’,4-lactone, 2-acetamido-6-O-acetyl-3-O-[(R)-1-carboxyethyl]-2-deoxy-alpha-D-glucopyranoside 1’,4-lactone, and 2-acetamido-6-O-acetyl-3-O-[(R)-1-carboxyethyl]-2-deoxy-alpha-D-glucopyranoside-1-alpha-(diphenyl phosphate) 1’,4-lactone on silica gel with ethyl acetate - acetone 2:1. TLC of triethylammonium muramyl phosphate on silica gel with isopropanol - water - 25 % ammonia 6:1:3. Evaluation under UV light and by heating the plate at 250 °C.

      Classification: 32a