Indian Drugs 41 (6), 362-365 (2004). HPTLC on silica gel with n-butane - n-propanol - glacial acetic acid - water - chloroform 4:1:1:1:2 with addition of formic acid in proportion of 1:0.001. Densitometric evaluation of ginkgo biloba extract by absorbance measurement at 254 nm. The same plate was used for the quantitative determination of ginseng at 520 nm after spraying with ninhydrin reagent. A simple, fast and precise HPTLC method has been developed for the simultaneous determination of ginkgo biloba and ginseng in solid dosage form.

IPC 56th 2004, Abstract No. G-5. HPTLC of conessine in Holarrhena antidysentrica, an important ayurvedic drug, on silica gel with toluene - ethyl acetate - diethyl amine 13:5:2. Detection by spraying with Dragendroff’s reagent. Quantitative determination by densitometric scanning at 520 nm. Different market samples of the drug were found to contain 0.30 - 1.46 % of conessine with recovery of 95.18 - 102.70 %

An improved analytical procedure. J. Planar Chromatogr. 17, 173-176 (2004). TLC of R,S-(+-)-ibuprofen and S-(+)-ibuprofen on silica gel prewashed with methanol - water 9:1 and impregnated with L-arginine by conventional dipping for 2 s in a 0.03 mol/L solution of the compound in methanol. One-dimensional development with acetonitrile - methanol - water 5:1:1 plus several drops of acetic acid to adjust the pH to 4.8, and two-dimensional chromatography with the same solvent mixture in two directions. Quantitation by densitometry at 210 nm.

Abstract G-9, IPC (2005). HPTLC of pantoprazole and mosapride in combined dosage form on silica gel with methanol - toluene - chloroform 4:30:15. Quantitative determination by absorbance measurement at 305 nm. The hRf value of pantoprazole was 31 and of mosapride 43, recovery was 99.9-101.1 %. Accuracy, precision, and linearity of the method were established.

J. Planar Chromatogr. 18, 384-387 (2005). TLC of thirty-seven N-[(4-arylpiperazin-1-yl)alkyl]-2-azaspiro[4.4]nonane- and [4.5]decane-1,3-dione derivatives on RP-18 in a pre-saturated chamber with n-propanol - Tris buffer (pH 7.0) mixtures. Detection under UV at 254 nm.

Part 1. Lipophilicity of 8-aryl-3-phenyl-6,7-dihydro-4H-imidazo[2,1-c][1,2,4]triazin-4-ones. J. Planar Chromatogr. 18, 274-281 (2005). Determination of the lipophilicity of 13 carbonyl derivatives of imidazo[1,2-c][1,2,4]triazine by TLC on RP-18 and RP-18 W in horizontal chambers with aqueous mobile phases containing organic modifiers (methanol or dioxane). Detection under UV light at 254 and 366 nm.

Abstract GP-41, IPC (2005). HPTLC of tizanidine in tablets on silica gel with ethyl acetate - methanol - acetic acid 60:4:1. Linearity range was 0.5-0.6 µg, LOQ 0.5 µg, and average recovery was 99.4-101.6 %. The method was validated according to ICH guidelines.

Indian Drugs 42 (10), 665-670 (2005). HPTLC of carbamazepine, phenytoin, and phenobarbitone extracted with ethyl acetate from human serum, on silica gel with toluene - acetone 5:2. Quantification by absorbance measurement at 217 nm. Rf values were 0.20 for carbamazepine, 0.41 for phenytoin, and 0.49 for phenobarbitone. The linearity (r=0.998) was in the range of 100-2000 ng. LOQ was found to be 30 ng/spot for carbamazepine and 80 ng/spot for phenytoin and phenobarbitone. The accuracy was in the range of 88.5 to 98.1 % and the CV in range of 1.1 to 3.9 %. Intra day and inter day reproducibility was comparable and within the stated limits.