Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      109 090
      Thin layer chromatographic method for the determination of flurbiprofen
      V. JAGATHI*, V. RAJESH, D. RAMESH, G. DEVALARAO (*K.V.S.R. Siddhartha College Pharmaceutical Sciences, Siddhartha Nagar, Vijayawada, A.P., India)

      Research Journal of Pharmaceutical, Biological and Chemical Sciences 2(1), 108-110 (2011). TLC of flurbiprofen in raw material and tablet dosage form on silica gel with chloroform - methanol - 25 % ammonia 45:5:3. Quantitative evaluation by absorbance measurement at 247 nm. The method was linear in the range of 50-600 ng/band. The sample was subjected to different stress conditions and all the degradation products were well resolved from the main compound. The method can therefore be used for stability studies.

      Classification: 32a
      110 062
      Statistical correlation and simultaneous estimation of atazanavir sulfate and ritonavir in fixed dosage form by high performance liquid chromatography and high-performance thin-layer chromatography
      Anindita BEHERA*, K. SETHY, Dannana SANKAR, S. MITRA, S. SI (*School of Pharmaceutical Sciences, Siksha O Anusandhan University, Bharatpur, Ghatikia, Bhubaneswar - 751003, Orissa, India, anindita02@gmail.com)

      J. Liq. Chromatogr. Relat. Technol. 35, 1731-1749 (2012). HPTLC of atazanavir sulfate (1) and ritonavir (2) in fixed dosage on silica gel with toluene – methanol – glacial acetic acid – ethyl acetate 14:1:3:4. Quantitative determination by absorbance measurement at 254 nm. The hRf values of (1) and (2) were 50 and 63, respectively. Linearity was 30-300 ng/zone for (1) and 10-100 ng/zone for (2). The intermediate/inter-day/intra-day precision was 0.3 % for (1) and 0.7 % for (2) (n=6). The limit of detection and quantification was 16 and 49 ng/zone for (1) and 18 and 55 ng/zone for (2), respectively. Recovery (by standard addition) was 99.9 % for (1) and (2). The results were in accordance with those by a validated HPLC method.

      Classification: 32a
      110 139
      Validated TLC and HPLC stability-indicating methods for the quantitative determination of dapsone
      A. SALAMA*, M. EL RIES, S. TOUBAR, M. HAMIDE, M. WALASH (*Pharmaceutical Chemistry Department, National Organization for Drug Control and Research, Giza, Egypt, salama_nahla2004@hotmail.com)

      J. Planar Chromatogr. 25, 65-71 (2012). HPTLC of dapsone in presence of its oxidative degradants on silica gel with acetate - toluene 1:1. Quantitative determination by absorbance measurement at 289 nm. Linearity was in the range of 0.5-6.0 µg/zone. Recovery was 99.4 %. The method showed comparable results to a validated HPLC method.

      Classification: 32a
      111 091
      Determination of lamotrigine in tablets using HPTLC, HPLC, and derivative spectrophotometry methods
      M. KOBA*, M. MARSZALL, W. SROKA, M. TLUCHOWSKA, T. BACZEK (*Department of Medicinal Chemistry, Faculty of Pharmacy, Collegium Medicum of Nicolaus Copernicus University, Bydgoszcz, Poland, kobamar@cm.umk.pl)

      J. Liq. Chromatogr. Relat. Technol. 36, 537-548 (2013). HPTLC of lamotrigine in tablets on silica gel with toluene - acetone - ammonia 6:14:1. Quantitative determination by absorbance measurement at 312 nm. The hRf value of lamotrigine was 55. LOD and LOQ were 0.57 and 1.73 µg/mL, respectively. Intermediate precision was below 1.9 %. Average recovery (by standard addition) was 101.5 %. Comparable results were obtained as compared with a validated HPLC method.

      Classification: 32a
      113 064
      Simultaneous estimation of amiloride hydrochloride and torsemide in their combined dosage forms by high-performance thin-layer chromatography
      S. BHADJA*, U. CHHALOTIYA, D. SHAH, F. MEHTA, K. BHATT (*Indukaka Ipcowala College of Pharmacy, Beyond GIDC, P.B. No. 53, Vitthal Udyognagar 388 121, Gujarat, India, bhadjasmit@gmail.com)

      J. Planar Chromatogr. 27, 294-298 (2014). HPTLC of amiloride hydrochloride (1) and torsemide (2) in dosage forms on silica gel with chloroform - methanol - ammonia 15:7:2. Quantitative determination by absorbance measurement at 286 nm. The hRF values for (1) and (2) were 46 and 24, respectively. Linearity was in the range of 50-300 ng/zone for (1) and 100-600 ng/zone for (2). The intermediate/inter-day/intra-day precision were below 4 % (n=3). The LOD and LOQ were 16 and 50 ng/zone for (1) and 33 and 100 ng/zone for (2), respectively. Recoveries for (1) and (2) were between 97.4 and 99.5 %.

      Classification: 32a
      115 064
      Male enhancement nutraceuticals in the Middle East market
      G. ELAGOURI, F. ELAMRAWY, A. ELYAZBI, A. ESHRA, M. NOUNOU* (*Department of Pharmaceutics of Pharmacy Alexandria University 1 El-Kartum Square Alexandria Egypt, mohamed.nounou@alexu.edu.eg, nounou@uh.edu)

      Int. J. Pharm. 492, 109-119 (2015). HPTLC of sildenafil on silica gel with chloroform - ethanol 9:1. Quantitative determination by absorbance measurement at 254 nm.

      Classification: 32a
      117 111
      Screening of three PDE5-inhibitors and eight of their analogs in lifestyle products
      Tiên DO (CAMAG, Sonnenmattstrasse 11, 4132 Muttenz, Switzerland, tien.do@camag.com)

      CBS 114, 9-10 (2015). HPTLC of phosphodiesterase type 5 inhibitors Viagra (sildenafil), Levitra (vardenafil), Cialis (tadalafil) and their analogs (hydroxyacetildenafil, homosildenafil, thiohomosildenafil, acetildenafil, acetaminotadalafil, propoxyphenyl, hydroxyhomosildenafil, hydroxyhomosildenafil, and_x000D_
      hydroxythiohomosildenafil) on silica gel with t-butyl methyl ether – methanol – 28 % ammonia 20:2:1 with chamber saturation, migration distance 70 mm. Detection under UV 254 and 366 nm. Densitometric evaluation by absorbance measurement at 232 nm. Identification of the substances based on their hRf values and distinctly different UV spectra.

      Classification: 32a
      119 098
      Validated chromatographic methods for the analysis of two binary mixtures containing pyridoxine hydrochloride
      N. HABIB, M. ABDELRAHMAN, N. ABDELWHAB, N. ALI (*Beni-Suef University, Faculty of Pharmacy, Pharmaceutical Analytical Chemistry Department, Alshaheed Shehata Ahmed Hegazy St, Beni-Suef 62514, Egypt, neeeven_magdy@yahoo.com)

      J. AOAC Int. 100, 414-421 (2017). HPTLC of two binary mixtures containing pyridoxine hydrochloride (1) with either cyclizine hydrochloride (2) or meclizine hydrochloride (3) on silica gel with dichloromethane – acetone – methanol 14:2:1. Quantitative determination by absorbance measurement at 220 nm. The hRF values for (1-3) were 7, 25 and 80, respectively. Linearity was in the range of 0.2-5 μg/zone for (1) and 0.2-4 μg/zone for (2) and (3). The LOD and LOQ were 60 and 190 ng/zone for (1), 50 and 170 ng/zone for (2) and 60 and 170 ng/zone for (3), respectively. The intermediate precision was <2 % (n=3). Average recovery rate was 99.9 % for (1) and (3) and 100.1 % for (2).

      Classification: 32a