J. Planar Chromatogr. 15, 192-195 (2002). HPTLC of rosiglitazone (and pioglitazone as internal standard) on silica gel after prewashing with methanol with ethyl acetate - toluene - methanol 45:55:1 after equilibration for 10 min. Densitometry at 242 nm. Limit of detection was found to be 40 ng; limit of quantitation 100 ng. New simple, specific, and sensitive method.

J. Planar Chromatogr. 15, 345-348 (2002). HPTLC of enoxacin, ofloxacin, and pefloxacin on silica gel in with dichloromethane - methanol - 25% NH3 14:10:3. Detection and quantification by videodensitometry at 254 nm and by classical densitometry at 263 nm for enoxacin, 290 nm for ofloxacin, and 275 nm for pefloxacin. Precision, expressed as RSD, was between 7.56 and 10.08.

J. Planar Chromatogr. 16, 19-22 (2003). TLC of fluoxetine [N-methyl-3-(4-trifluoromethylphenoxy)-3-phenyl-propylamine]and paroxetine [(-)-trans-5-[(4-p-fluorophenyl-3-piperidyl)methoxy]-1,3-benzodioxol]on silica gel with benzene - acetone - ethanol - NH3 9:7:2:1. Detection of fluoxetine by densitometry at 218 nm and of paroxetine at 293 nm. Video densitometry at 254 nm for both drugs. The range of linearity was 2-10 µg/spot for fluoxetine and 0.5-8 µg/spot paroxetine. RSD was less than 4.3% for densitometry and less than 4.9% for videodensitometry. New, simple, rapid, and accurate methods.

J. Planar Chromatogr. 16, 271-275 (2003). TLC of chlorpropamide, tolbutamide, glibenclamide, metformin, pioglitazone, rosiglitazone, and repaglinide on silica gel and oxide with mixtures of chloroform, ether, and ethyl acetate. For more effective resolution aqueous ammonia or acetic acid was added to the mobile phase. Silica enabled better separation than alumina. Reversed-phase chromatography was performed on RP-18 with mixtures of acetonitrile or 2-propanol with phosphate buffer. For the separation of these drugs RP chromatography was more effective than use of normal-phase mode. Determination under UV 254 nm. Systematic optimization of separation conditions.

CBS 92, 1-3 (2004). HPTLC of cinchocaine hydrochloride from suppositories on silica gel with 1-butanol - toluene - ethanol - water - 100 % acetic acid 10:8:7:4:1 over 30 mm followed by heating at 110 °C for 10 min. Quantitative determination by fluorescence measurement at 313/>400 nm.Precision is 2 % and recovery 101 %.

Indian Drugs 41 (3), 149-152 (2004). HPTLC on silica gel with toluene - ethyl acetate 1:24. Quantitative determination by absorbance measurement at 260 nm. The linearity range is 100-500 µg/µL and recovery is 100.7 %. The method was validated and compared with HPLC. The results were comparable. Advantages of HPTLC in terms of handling many samples. Thus, a simple, fast and precise HPTLC method was developed for quantification of ebastine in tablets.

J. Planar Chromatogr. 17, 75-78 (2004). HPTLC of montelukast sodium (1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyk)phenyl]-propyl]thio]methyl] cyclopropane acetic acid monosodium salt) and nimesulide (N-(4-nitro-2-phenoxyphenyl)methane sulfonamide or 4-nitro-2-phenoxymethanesulfonanilide) as internal standard on pre-washed silica gel with toluene - ethyl acetate - glacial acetic acid 60:34:1 in a twin-trough chamber. Quantitative determination at 344 nm.

J. Planar Chromatogr. 17, 383-387 (2004). TLC of fenbufen, ibuprofen, ketoprofen, diclofenac sodium, mefenamic acid, and tiaprofenic acid on silica gel by ascending and horizontal techniques, and on RP-18 in horizontal chambers. Good separation was achieved on silica gel by horizontal development with chloroform - methanol - 25 % ammonia 67:25:8; reversed phase chromatography on RP-18 with 0.15 mol/L phosphate buffer, pH 5.73 - 10 % CTMA-Br (N-cetyl-N,N,N-trimethylammonium bromide) in methanol 7:13 enabled better separation of the six drugs. Detection under UV light at 254 nm - for ibuprofen detection was best achieved after normal phase chromatography with 20 % aqueous sodium carbonate solution. A simple videodensitometric procedure was developed and validated. RSD for quantitation of fenbufen was 2.44 - 3.10 %.