J. Planar Chromatogr. 15, 56-58 (2002). TLC of triclocarban (3,4,4'-trichlorocarbanilide) on silica gel with n-hexane - ethanol 24:1. Quantification by densitometry at 260 nm. Limit of detection 25 ng, good linear relationship within the range of 600 - 1300 ng, selectivity, precision, and accuracy make the method suitable for routine quality-control analysis.

J. Liq. Chrom. & Rel. Technol. 24, 2873-2878 (2001). HPTLC of meclizine (1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine) dihydrochloride on silica gel with n-butanol - deionized water - acetic acid 17:2:1. Quantification by densitometry at 254 nm. Precision (relative standard deviation) was 1.58 and 1.26% for replicate analyses of two tablets. The error of standard addition analysis performed to evaluate accuracy was 0.506%.

Indian Drugs 39 (8), 434-440 (2002). HPTLC on silica gel with chloroform - methanol - water 85:12:3. The method was validated for linearity (50 - 150 ng), accuracy and precision. A simple and rapid HPTLC method. Comparable with HPLC regarding sensitivity.

Proc. Intern. Symp. on Planar Separations Plan. Chrom. 185-189 (2003). OPLC of norsteroids (e.g. 19-nortestosterone, estradiol-methylether-acetate) on silica gel with different mixtures of toluene, chloroform, butyl acetate, and hexane, i.e. toluene - chloroform - cyclohexane - butyl acetate 55:3:40:2.Visualization by spraying with 10% sulfuric acid in ethanol and heating at 120°C for 2 min. Also visual evaluation under UV 254 and 366 nm before and after spraying. Use of a video documentation system.

Correlation with the lipophilicity of the compounds. J. Planar Chromatogr. 16, 363-368 (2003). Study of structure-activity relationship TLC of 12 differently substituted 2,4-dioxotetrahydro-1,3-thiazoles (4'-dimethylamino-benzylidene-, 1'-naphthylidene-, 2'-oxybenzylidene-, 3',4'-methylenedioxybenzylidene-, benzylidene-, 3'-thienylidene-, 3',4'-dimethoxybenzylidene-, 4'-bromobenzylidene-, 5'-methyl-2'-furfurylidene-, 4'-benzyloxybenzylidene-, 4'-ethoxybenzylidene-) on silica gel with hexane - ethyl acetate, hexane - acetone, and hexane - dioxane and on paraffin oil-impregnated silica gel with NH3 conc. - methanol, NH3 conc. - dioxane, and NH3 conc. - acetone in different ratios. Visualization under UV 254 nm.

CBS 93, 10-12 (2004). HPTLC of progesterone on silica gel prewashed by development in AMD2 first with chloroform - methanol 1:1 and then with the mobile phase, followed by drying at 80 °C for 15 min. Development in AMD2 with toluene - 2-propanol 10:1 without preconditioning over 60 mm. Quantitative determination by absorbance measurement at 252 nm followed by spectra recording from 200 to 360 nm. The linear working range is 25.7-154.5 ng/zone. Repeatability (standard deviation calculated from the amounts of seven simulated progesterone samples determined on the same plate at three concentration levels in the lower, middle and upper range) is 0.26-1.29 %. Recovery is 99.88-100.97 %. Reproducibility was performed with recycled HPTLC plates.

Indian Drugs 41 (8), 482-487 (2004). HPTLC on silica gel with toluene - acetone - ammonia 50:50:1. Quantitative determination by absorbance measurement at 315 nm. The method was validated in terms of linearity (300-1000 ng/spot), precision, accuracy, and specificity. For the content uniformity test the tizanidine hydrochloride content of 10 individual tablet units of two market formulations was determined after extracting with methanol. Both formulations compiled with the USP specification. The proposed content uniformity allows the parallel analysis of ten tablets on a single plate and provides a faster and cost-effective quality control tool for routine analysis. A simple, sensitive HPTLC content uniformity test was developed and validated for the analysis of tizanidine hydrochloride in its commercial single component tablet formulations (2 mg/tablet).

J. Planar Chromatogr. 17, 255-260 (2004). TLC of fourteen 1-arylpiperazine derivatives on silica gel with monocomponent and binary non-polar mobile phases and on RP-18 with binary mobile phases comprising mixtures of methanol, acetone, or dioxane (as organic modifiers) and water in a horizontal chamber after equilibration for 15 min. Detection under UV light at 254 nm.