Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      109 103
      Development and validation of an HPTLC method for determination of olanzapine in formulations
      R.B. PATEL, M.R. PATEL*, K.K. BHATT, B.G. PATEL (*Sardar Patel University, Indukaka Ipcowala College of Pharmacy, New Vallabh Vidyanagar-388 121, Gujarat, India; rashmru@gmail.com)

      J. AOAC Int. 93, 811-819 (2010). HPTLC of olanzapine on silica gel (prewashed twice with methanol) with methanol - ethyl acetate 4:1 in a twin-trough chamber saturated for 20 min at 25 +/- 2 °C. Quantitative determination by densitometry in absorbance mode at 285 nm. The hRf was 35. Linearity was between 100 and 600 ng/band for olanzapine. LOD was 24 ng/band and LOQ 91 ng/band. The average recovery (n = 6) was 100.4 %. The %RSD of intra-day and inter-day precision (n = 5) was between 0.2-1.4 %.

      Classification: 32a
      110 071
      Stability-indicating HPTLC method for simultaneous estimation of amlodipine besylate, hydrochlorothiazide and olmesartan medoxomil in combined tablet dosage forms
      N. DUBEY*, A. JAIN, A. RAGHUWANSHI, D. JAIN (*College of Pharmacy, IPS Academy, Indore-452015, Madhya Pradesh, India, nitindubeympharm@yahoo.com)

      J. Planar Chromatogr. 25, 475-480 (2012). HPTLC of amlodipine besylate (1), hydrochlorothiazide (2) and olmesartan medoxomil (3) on silica gel with chloroform - ethyl acetate - toluene - methanol - glacial acetic acid 39:39:77:39:6. Quantitative determination by absorbance measurement at 230 nm. The hRf of compounds (1) to (3) were 31, 56 and 81, respectively. Linearity was in the range of 200-4800 ng/band for (1), 100-4000 ng/band for (2) and 200-5200 ng/band for (3). Limits of detection and quantification were 35 and 101 ng/band for (1), 20 and 59 ng/band for (2) and 48 and 144 ng/band for (2), respectively. Intermediate/inter-day/intra-day precision was below 1.0 % (n=6). Mean recovery was between 100.0 and 100.3 % for all active agents.

      Classification: 32a
      110 150
      Stability-indicating HPTLC method for the determination of atorvastatin and ezetimibe - application to pharmaceutical dosage forms
      S. WALODE*, A. KASTURE, S. WADODKAR (*Sinhgad Institute of Pharmaceutical Sciences, Kusgaon (Bk), Lonavala, Pune 410401, Maharashtra, India, sanjuwalode@rediffmail.com)

      J. Planar Chromatogr. 25, 81-84 (2012). HPTLC of atorvastatin (1) and ezetimibe (2) on silica gel with methanol - toluene - chloroform - triethylamine 2:16:1:1. Quantitative determination by absorbance measurement at 259 nm. The hRf values of compounds (1) and (2) were 7 and 37, respectively. Linearity was in the range of 500-1500 ng/band for both (1) and (2). Intermediate/inter-day/intra-day precision was below 2 % (n=3). Mean recovery was 99.7 % for both active agents.

      Classification: 32a
      111 107
      Rapid and sensitive simultaneous estimation of metformin hydrochloride and pioglitazone hydrochloride in tablet formulation by HPTLC method
      D. MODI*, B. PATEL (*Institute of Pharmaceutical Education and Research, Department of Pharmaceutical Chemistry, Kadi Sarva Vishwavidyalaya, Gandhinagar-382023, Gujarat, India, darshana_pharma@yahoo.co.in)

      J. Liq. Chromatogr. Relat. Technol. 36, 618-627 (2013). HPTLC of metformin hydrochloride (1) and pioglitazone hydrochloride (2) in tablet on silica gel with butanol - 1,4-dioxane - glacial acetic acid 5:3:2. Quantitative determination by absorbance measurement at 226 nm. The hRf values of (1) and (2) were 36 and 73, respectively. Linearity was in the range of 2-20 µg/zone for (1) and 60-600 ng/zone for (2). LOD and LOQ were 630 and 1909 ng/zone for (1) and 9 and 26 ng/zone for (2). Intermediate precision was below 1.0 %. Average recovery (by standard addition) for (1) and (2) was 99.4 % and 98.5 %, respectively.

      Classification: 32a
      113 091
      Screening method to study the reactivity of cosmetic UV filters on skin proteins
      W. SCHWACK*, Constanze STIEFEL (*Institute of Food Chemistry, University of Hohenheim, 70599 Stuttgart, Germany, wolfgang.schwack@uni-hohenheim.de)

      CBS 111, 7-9 (2013). HPTLC of benzophenone-3 (BP-3), butyl methoxydibenzoyl-_x000D_methane (BM-DBM), 3-benzylidene camphor (3‑BC), 4‑methylbenzylidene camphor (4‑MBC), octocrylene (OCR), ethylhexyl methoxycinnamate (EHMC), ethyl-hexyl salicylate (EHS), diethylhexyl butamido triazone (DEBT), octyldimethyl p-aminobenzoic acid (OD-PABA), 2-hydroxy-4-methoxy-benzophenone-5-sulfonic acid (HMBS), ethylhexyl triazone (EHT) on amino phase with petroleum ether - t-butyl-methyl ether - methanol 7:2:1 and 1 % triethylamine (HMBS with methanol – acetic acid 9:1), migration distance max. 48 mm from lower edge. For reaction with the UV filters the plate was stored up to 2 h in a dark at room temperature, then heated to 33 °C, and irradiated under natural sunlight or with a Suntest CPS+ at 350 W/m2. Quantitative absorbance measurement at UV 254 nm. The UV filters known as common triggers for photoallergic reactions showed the greatest tendency to bond to the amino phase. Thus, the developed screening method is well suited to estimate the potential of_x000D_ different UV filters to form protein adducts and to identify possible skin sensitizers.

      Classification: 32a
      115 068
      Quantitative determination of rivastigmine from a new biodegradable microparticulate system by high-performance thin-layer chromatography
      Sigrid MENNICKENT*, A. MIRANDA, Carolina GOMEZ, M. VEGA, Gisela RIOS, Marta DE DIEGO (*Department of Pharmacy, Faculty of Pharmacy, University of Concepcion, P.O. Box 237, Concepcion, Chile, smennick@udec.cl)

      J. Planar Chromatogr. 28, 251-255 (2015). HPTLC of rivastigmine on silica gel with toluene - acetonitrile - formic acid 6:3:1. Quantitative determination by absorbance measurement at 540 nm. The hRF value for rivastigmine was 41. Linearity was in the range of 125-1250 ng/zone. LOD and LOQ were 22 and 66 ng/zone, respectively. The intermediate precision was below 8 % (n=3). Recovery ranged between 99 and 102 %.

      Classification: 32a
      117 121
      Optimization of TLC method for separation and determination of ziprasidone and its impurities
      D. OBRADOVIC, S. FILIPIC, K. NIKOLIC, M. CARAPIC, D. AGBABA* (*Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe
      450, Belgrade 11000, Serbia, danica@pharmacy.bg.ac.rs)

      J. Liq. Chromatogr. Relat. Technol. 39, 271-276 (2016). HPTLC of ziprasidone and its impurities on silica gel with toluene – methanol – glacial acetic acid 15:1:1. Quantitative determination by absorbance measurement at 250 and 320 nm. The hRF value was 42 for ziprasidone and 19, 28, 31, 58 and 70 for its impurities. LOQ of impurities was 25 ng/zone. Recovery was between 94.9 and 106.7 %. See also J. Planar Chromatogr. 29, 239-246 (2016).

      Classification: 32a
      119 102
      Simultaneous densitometric analysis of amlodipine, hydrochlorothiazide, lisinopril, and valsartan by HPTLC in pharmaceutical formulations and human plasma
      J. PANDYA, M. SANYAL, P. SHRIVASTAV* (*Department of Chemistry, School of Sciences, Gujarat University, Navrangpura, Ahmedabad, Gujarat, India, pranav_shrivastav@yahoo.com)

      J. Liq. Chromatogr. Relat. Technol. 40, 467-478 (2017). HPTLC of lisinopril (1), amlodipine (2), valsartan (3) and hydrochlorothiazide (4) in pharmaceutical formulations and in human plasma on silica gel with methanol – dichloromethane – glacial acetic acid 90:10:1. Quantitative determination by absorbance measurement at 215 nm. The hRF values for (1) to (4) were 29, 56, 67 and 75, respectively. Linearity was between 400 and 2000 ng/zone for (1), 200 and 1500 ng/zone for (2), 1000 and 7000 ng/zone for (3) and 300 and 1500 ng/zone for (4). LOD and LOQ were 83 and 252 ng/zone for (1), 54 and 164 ng/zone for (2), 156 and 474 ng/zone for (3) and 77 and 234 ng/zone for (4), respectively. The intermediate precision was <3 % (n=6). Recovery rate ranged from 99.3 to 100.9 % for (1-4).

      Classification: 32a