J. Planar Chromatogr. 11, 254-257 (1998). TLC of salbutamol sulfate and bromhexine hydrochloride on silica gel with methanol - chloroform - triethylamine 110:90:1. Densitometry at 276 nm. Calibration curves were linear in the concentration range 20 - 580 ng/µl for both compounds. Recoveries were 98.84%; 99.0% and 99.62%; 99.63%, respectively. Simple, rapid and precise quantitative TLC method.

J. AOAC Int. 82, 31-37 (1999). Examination of the retention behavior of 10 dihydroxythiobenzanilides for acquisition of log k' data. With water-acetone mixtures as the mobile phases, the concentration range for which the correlation between log k' and acetone concentration is linear was established for each stationary phase and used to determine hydrophobicity parameters log k'w by linear extrapolation. TLC on RP-8 and RP-18 in a sandwich chamber with chamber saturation with organic solvent vapor. Water-acetone was applied as mobile phase, with the concentration of acetone in the range 0.3-1.0v/v at increments of 0.05 v/v. Detection by densitometry at 325 nm.

J. Liq. Chrom. & Rel. Technol. 22, 153-159 (1999). HPTLC of diphenhydramine hydrochloride on silica gel (after pre-cleaning of the plate by development to the top with dichloromethane - methanol 1:1) with ethyl acetate - methanol - NH3 17:2:1. Densitometry at 260 nm.

(Spanish). Bol. Soc. Chil. Quim. 44, 479-485 (1999). HPTLC validation of metamizol-Na on silica gel with ethyl acetate - methanol - NH3 (75:24:1) to 50 mm. Quantitation by densitometry at 273 nm by linear regression (50-250 ng). Limit of detection is 10,9 ng and limit of quantification 16,1 ng. CV is 2,45%, recovery is 102,48% (225 ng), 98,78% (250 ng) and 100,69% (275 ng). The HPTLC method is precise, exact, proportional, linear and sensitive. Results do not differ statistically from the Official Method described in the German Pharmacopoeia.

J. Planar Chromatogr. 13, 420-425 (2000). HPTLC of 18 2,4-dihydroxythiobenzanilides on RP-18 with mixtures of water with organic modifier (acetone or methanol) at concentrations from 0.4 to 0.75 at intervals of 0.5. Detection by densitometry at 325 nm. Determination of physicochemical parameters (retention factors, log kw, and hydrophobicity, A12) describing the structural properties and phase affinity of 2,4-dihydroxythiobenzanilides. The parameters obtained were further used to estimate the hydrophobic character and biological activity of the compounds examined.

Indian Drugs 39 (2), 96-100 (2002). HPTLC on silica gel with chloroform - benzene - methanol 7:2:1. Quantification by densitometry.

Part 1. Lipophilicity of pyrimido[5,4-c]quinolin-4(3H)-ones and 1,2,3,4-tetrahydropyrimido[5,4-c]quinolin-2,4-diones. J. Planar Chromatogr. 15, 169-175 (2002). Determination of the lipophilicity of new bioactive pyrimido[5,4-c]quinolin-4(3H)-ones and 1,2,3,4-tetrahydropyrimido[5,4-c]quinolin-2,4-diones by RP-TLC with DMF-TRIS buffer. TLC of nine derivatives of N-3-substituted 2-methylpyrimido[5,4-c]quinolin-4(3H)ones and three derivatives of 1,2,3,4-tetrahydropyrimido[5,4-c]quinolin-2,4-diones on RP-18. Detection under UV. Experimental lipophilicity was determined by the use of calibration curves obtained under same measurement conditions for a set of six standards of known experimental lipophilicity.

J. Planar Chromatogr. 15, 410-413 (2002). TLC of nicotinic acid and derivatives (methyl nicotinate, ethyl nicotinate, isopropyl nicotinate, butyl nicotinate, hexyl nicotinate, benzyl nicotinate, nicotinamide, N-methylnicotinamide, N,N-diethylnicotinamide) on silica gel and silica gel kieselguhr with mixtures of acetone and n-hexane in different volume proportions, on RP silica gel with methanol - water 9:1, 8:2, and 7:3, on polyamide 11 with mixtures of benzene and methanol. Detection under UV 254 nm.