Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      74 092
      Quantitative TLC of erythromycin - application to commercial bulk samples and biological samples
      K. KHAN, J. PAESEN, E. ROETS, J. HOOGMARTENS*, (*Katholieke Universiteit Leuven, Lab. voor Farm. Chem., Fac. Farm. Wetenschappen, Van Evenstraat 4, B-3000 Leuven, Belgium)

      J. Planar Chromatogr. 7, 349-353 (1994). TLC on silica with dichloromethane - methanol - 25% NH3 60:6:1. Detection by spraying with 0.15% xanthydrol in hydrochloric acid conc. - acetic acid 60:5, followed by heating. Quantification by densitometry at 525 nm. Comparison of TLC with LC. This TLC method can be used for rapid and simple quantification of erythromycin in urine and plasma samples.

      Classification: 28a
      78 091
      Separation and identification of some cephalosporins on impregnated TLC plates
      R. BHUSHAN*, V. PARSHAD, (Dept. Chem., Univ. Roorkee, Roorkee-247-667, India)

      Biomed. Chromatogr. 10, 256-260 (1996). TLC on silica impregnated with EDTA in different concentrations with 1) propionic acid - 2-propanol - water 2:1:1, 2) 2-propanol - water - ethyl acetate 5:3:3, 3) butanol - water - acetic acid 5:4:2. Detection by exposure to iodine vapor. Discussion of the effects of the concentration of the impregnating reagent and the composition of the mobile phase on the resolution.

      Classification: 28a
      82 080
      Quantitation of antibiotics by densitometry on a hydrocarbon-impregnated silica gel HPTLC plate
      S.C. DHANESAR, (SCD Sci. Sol., 14 Carissa Court, Owings Mills, MD 21117, USA)

      Part I: Evaluation of the HPTLC plate. J. Planar Chromatogr. 11, 195-200 (1998). Description of the use of scanning densitometry to evaluate a hydrocarbon-impregnated HPTLC plate for the direct quantitation of antibiotics without prior plate elution. HPTLC of ceftriaxone on silica gel impregnated with hydrocarbons with different solvents - 95% ethanol, 3% trehalose, 0.1 N HCl, 1 N NaOH, 100 mM 7.5 phosphate buffer. Quantitation by densitometry. The results demonstrated that hydrocarbon-impregnated silica gel HPTLC plates can be used for direct determination of antibiotics without elution.

      Keywords:
      Classification: 28a
      89 091
      Separation of aminoglycosides by normal- and reversed-phase TLC
      R. BHUSHAN*, M. ARORA, (*Dept. of Chem., Indian Inst. of Techn., Roorkee-247 667, India)

      J. Planar Chromatogr. 14, 435-438 (2001). TLC of streptomycin, kanamycin, gentamycin, and tobramycin on silica gel and RP-18 with acetone - 2% sodium acetate - acetic acid - butanone 7:6:4:1 for normal-phase TLC, and acetonitrile - 5mM sodium acetate buffer (pH 4.6) 2:9 for reversed-phase TLC. Visualization by iodine vapor. The minimum detection limits were in the range of 0.4 - 0.6 µg.

      Keywords:
      Classification: 28a
      96 063
      Densitometric determination of some bioactive guanidinium compounds without post-derivatization
      A. Szabo, B. Erdélyi*, J. Salát, G. Máté (*Fermantation Pilot Plant, IVAX Drug Research Institute, Berlini u. 47-49, 1049 Budapest, Hungary)

      J. Planar Chromatogr. 18, 203-206 (2005). TLC of primycin (a mixture of related compounds), streptomycin, dihydrostreptomycin on silica gel with A) n-butanol - water - methanol - acetic acid 4:2:1:1; and B) chloroform - methanol - water - 35% formic acid - n-butanol - formaldehyde 160:53:9:6:3:3. When using phase B repeated development improved the resolution. After development the plates were dried in a vacuum chamber at 100 °C. An efficient prewashing technique (with methanol - 35 % formic acid 1:1 followed by drying with hot air) made the TLC plates suitable for densitometric measurements at short wavelengths. Quantitative determination by absorbance measurement at 200 nm.

      Classification: 28a
      104 050
      HPTLC determination of cefuroxime axetil and ornidazole in combined tablet dosage form
      P.N. RANJANE*, S.V. GANDHI, S.S. KADUKAR, K.G. BOTHARA, (*Department of Pharmaceutical Analysis, A.I.S.S.M.S. College of Pharmacy, Kennedy Road, Near R.T.O., Pune 411 001, India)

      J. Chromatogr. Sci. 48 (1), 26-28 (2010). HPTLC of cefuroxime axetil and ornidazole in combined tablet dosage form on silica gel with toluene - n-butanol - triethylamine 17:4:1. The hRf value of ornidazole was 51 and of cefuroxime axetil 67. Quantification by densitometry at 285 nm. Linearity was between 100 and 500 ng/band for both cefuroxime axetil and ornidazole. The method was used for the assay of the compounds in pharmaceutical formulations. The content of cefuroxime axetil was 102.4 % and of ornidazole 101.0 %.

      Classification: 28a
      109 059
      Simultaneous identification and quantitative analysis of eight cephalosporins in pharmaceutical formulations by TLC-densitometry
      Monika DABROWSKA*, M. STAREK, S. PIKULSKA (*Jagiellonian University, Collegium Medicum, Department of Inorganic and Analytical Chemistry, Medyczna 9, Kraków, Poland; mtylka@cm-uj.krakow.pl)

      J. Planar Chromatogr. 24, 23-29 (2011). TLC of cephalexin, cefadroxil, cefazolin, cefaclor, cefuroxime axetil, ceftriaxone, and cefotaxime on silica gel with chloroform - ethyl acetate - glacial acetic acid - water 4:4:4:1. Quantitative determination by absorbance measurement at 275 nm. Accuracy was in the range of 98.3-100.8 % and precision (%RSD) was 0.4-2.5 %. LOQ were 0.1 µg/L for cefuroxime and 2.8 µg/L for cefotaxime. The method was highly reproducible with inter- and intra-day precisions between 0.24-0.25 %.

      Classification: 28a
      113 055
      Analysis of active ingredients, lumefantrine and artemether in combined antimalarial tablet by HPTLC with densitometric measurement before and after derivatization
      S. MEENA, S. SANDHYA* (*Department of Pharmaceutical Analysis, Devaki Amma Memorial College of Pharmacy, Chelembra, Malappuram 673634, Kerala, India, sandhyashiji82@gmail.com)

      J. Liq. Chromatogr. Relat. Technol. 37, 1416-1426 (2014). HPTLC of lumefantrine (1) and artemether (2) on silica gel with toluene – ethyl acetate – acetic acid 4:15:5. Detection by dipping into a derivatization reagent (10 % each of methanolic concentrated sulfuric acid and anisaldehyde), followed by heating at 110 °C for 3 min. Quantitative determination by absorbance measurement at 519 nm. The hRF values for (1) and (2) were 55 and 70, respectively. Linearity was in the range of 60-360 ng/zone for (1) and 10-60 ng/zone for (2). The intermediate/interday/intra-day precisions were below 1 % (n=3). The LOD and LOQ were 7 and 26 ng/zone for (1) and 2 and 6 ng/zone for (2), respectively. Recoveries were between 97.6-101.3 % for both (1) and (2).

      Classification: 28a