Cumulative CAMAG Bibliography Service CCBS
Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.
The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:
- Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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J. Planar Chromatogr. 7, 349-353 (1994). TLC on silica with dichloromethane - methanol - 25% NH3 60:6:1. Detection by spraying with 0.15% xanthydrol in hydrochloric acid conc. - acetic acid 60:5, followed by heating. Quantification by densitometry at 525 nm. Comparison of TLC with LC. This TLC method can be used for rapid and simple quantification of erythromycin in urine and plasma samples.
Biomed. Chromatogr. 10, 256-260 (1996). TLC on silica impregnated with EDTA in different concentrations with 1) propionic acid - 2-propanol - water 2:1:1, 2) 2-propanol - water - ethyl acetate 5:3:3, 3) butanol - water - acetic acid 5:4:2. Detection by exposure to iodine vapor. Discussion of the effects of the concentration of the impregnating reagent and the composition of the mobile phase on the resolution.
Part I: Evaluation of the HPTLC plate. J. Planar Chromatogr. 11, 195-200 (1998). Description of the use of scanning densitometry to evaluate a hydrocarbon-impregnated HPTLC plate for the direct quantitation of antibiotics without prior plate elution. HPTLC of ceftriaxone on silica gel impregnated with hydrocarbons with different solvents - 95% ethanol, 3% trehalose, 0.1 N HCl, 1 N NaOH, 100 mM 7.5 phosphate buffer. Quantitation by densitometry. The results demonstrated that hydrocarbon-impregnated silica gel HPTLC plates can be used for direct determination of antibiotics without elution.
J. Planar Chromatogr. 14, 435-438 (2001). TLC of streptomycin, kanamycin, gentamycin, and tobramycin on silica gel and RP-18 with acetone - 2% sodium acetate - acetic acid - butanone 7:6:4:1 for normal-phase TLC, and acetonitrile - 5mM sodium acetate buffer (pH 4.6) 2:9 for reversed-phase TLC. Visualization by iodine vapor. The minimum detection limits were in the range of 0.4 - 0.6 µg.
J. Planar Chromatogr. 18, 203-206 (2005). TLC of primycin (a mixture of related compounds), streptomycin, dihydrostreptomycin on silica gel with A) n-butanol - water - methanol - acetic acid 4:2:1:1; and B) chloroform - methanol - water - 35% formic acid - n-butanol - formaldehyde 160:53:9:6:3:3. When using phase B repeated development improved the resolution. After development the plates were dried in a vacuum chamber at 100 °C. An efficient prewashing technique (with methanol - 35 % formic acid 1:1 followed by drying with hot air) made the TLC plates suitable for densitometric measurements at short wavelengths. Quantitative determination by absorbance measurement at 200 nm.
J. Chromatogr. Sci. 48 (1), 26-28 (2010). HPTLC of cefuroxime axetil and ornidazole in combined tablet dosage form on silica gel with toluene - n-butanol - triethylamine 17:4:1. The hRf value of ornidazole was 51 and of cefuroxime axetil 67. Quantification by densitometry at 285 nm. Linearity was between 100 and 500 ng/band for both cefuroxime axetil and ornidazole. The method was used for the assay of the compounds in pharmaceutical formulations. The content of cefuroxime axetil was 102.4 % and of ornidazole 101.0 %.
J. Planar Chromatogr. 24, 23-29 (2011). TLC of cephalexin, cefadroxil, cefazolin, cefaclor, cefuroxime axetil, ceftriaxone, and cefotaxime on silica gel with chloroform - ethyl acetate - glacial acetic acid - water 4:4:4:1. Quantitative determination by absorbance measurement at 275 nm. Accuracy was in the range of 98.3-100.8 % and precision (%RSD) was 0.4-2.5 %. LOQ were 0.1 µg/L for cefuroxime and 2.8 µg/L for cefotaxime. The method was highly reproducible with inter- and intra-day precisions between 0.24-0.25 %.
J. Liq. Chromatogr. Relat. Technol. 37, 1416-1426 (2014). HPTLC of lumefantrine (1) and artemether (2) on silica gel with toluene – ethyl acetate – acetic acid 4:15:5. Detection by dipping into a derivatization reagent (10 % each of methanolic concentrated sulfuric acid and anisaldehyde), followed by heating at 110 °C for 3 min. Quantitative determination by absorbance measurement at 519 nm. The hRF values for (1) and (2) were 55 and 70, respectively. Linearity was in the range of 60-360 ng/zone for (1) and 10-60 ng/zone for (2). The intermediate/interday/intra-day precisions were below 1 % (n=3). The LOD and LOQ were 7 and 26 ng/zone for (1) and 2 and 6 ng/zone for (2), respectively. Recoveries were between 97.6-101.3 % for both (1) and (2).