Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      127 019
      Optimization of processing parameters for the microencapsulation of soursop (Annona muricata L.) leaves extract: Morphology, physicochemical and antioxidant properties
      O. JORDAN, P. GLORIO, L. VIDAL (*Universidad Le Cordon Bleu, Facultad de Ciencias de los Alimentos. Av. Salaverry 3180, Lima, Peru,

      Sci. Agropecu. 12, 161-168 (2021). HPTLC of annonacin in the leaves of soursop (Annona muricata) and microencapsulated extract on silica gel with chloroform - cyclohexane - diethylamine 2:1:1. Quantitative determination by absorbance measurement at 210 nm. 

      Classification: 23
      127 035
      Stability assessment of tamsulosin and tadalafil co-formulated in capsules by two validated chromatographic methods
      M. REZK, E. MOETY, M. WADIE*, M. TANTAWY (*Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, KasrEl-Aini Street, ET-11562, Cairo, Egypt,

      J. Sep. Sci. 44, 530-538 (2021). HPTLC of tamsulosin (1) and tadalafil (2) in presence of their degradation products (2) and (3) on silica gel with ethyl acetate - toluene - methanol - ammonia 20:10:20:3. Quantitative determination by absorbance measurement at 280 nm. The hRF values for (1) to (4) were 55, 68, 14 and 24, respectively. Linearity was between 0.5 and 25 µg/zone for (1) and (2). Intermediate precision was below 2 % (n=3). Average recovery was 99.7 % for (1) and 100.3 % for (2).

      Classification: 23e, 32a
      127 038
      Chromatographic methods for the determination of aminexil, pyridoxine, and niacinamide in a novel cosmetic hair preparation
      M. REZK, H. ESSAM, E. AMER, D. YOUSSIF (*National Organization for Drug Control and Research, Wezaret El-Zeraa st., Dokki, Giza, Egypt,

      J. AOAC Int. 103, 1167-1172 (2020). HPTLC of aminexil (1), niacinamide (2) and pyridoxine HCl (3) on silica gel with propanol - toluene - 33 % ammonia solution
      20:30:1. Quantitative determination by absorbance measurement at 270 nm. Linearity was between 0.25 and 1.25 µg/zone for (1), 2 and 7 µg/zone for (2) and 3 and 7 µg/zone for (3). Intermediate precision was below 2 % (n=3). The LOD and LOQ were 20 and 60 ng/zone for (1), 180 and 540 ng/zone for (2) and 140 and 430 ng/zone for (3), respectively. Average recovery was 100.1 % for (1) and (2) and 101.1 % for (3). 

      Classification: 23
      127 007
      Carotenoid composition and antioxidant potential of Eucheuma denticulatum, Sargassum polycystum and Caulerpa lentillifera.
      V. BALASUBRAMANIAM*, L. JUNE CHELYN, S. VIMALA, M.N. MOHD FAIRULNIZAL, I.A. BROWNLEE, I. AMINE (*Nutrition, Metabolism & Cardiovascular Research Centre, Institute for Medical Research, Ministry of Health Malaysia, Shah Alam, Selangor, Malaysia;

      Heliyon 6(8), e04654 (2020). HPTLC of ethanolic extracts of three algae (100µg/band) on silica gel, along with carotenoid standards (10µg/band), developed with toluene – acetone 7:3. Detection under white light. Carotenoids appeared orange or yellow, chlorophylls green, pheophytins dark khaki. Carotenoid patterns of the algae were very different depending on the family: red alga Eucheuma denticulatum (Solieriaceae) contained mainly zeaxanthin and lutein (hRF 44) and β-carotene (hRF 88), but also β-cryptoxanthin (hRF 69-71) and fucoxanthin (hRF 39); brown alga Sargassum polycystum (Sargassaceae) contained mainly fucoxanthin, and also cryptoxanthin; green alga Caulerpa lentillifera (Caulerpaceae) contained mainly zeaxanthin, but also astaxanthin (hRF 61) and canthaxanthin (hRF 77) in smaller amounts. Separately, HPLC-MS was used to confirm and quantify these compounds, which was necessary for carotenoids with similar hRF values: zeaxanthin and lutein (hRF 44), and β-carotene and lycopene (hRF 88).

      Classification: 11c, 15a, 23a, 32e
      127 065
      Development and validation of thin‑layer chromatography and high‑performance thin‑layer chromatography methods for the simultaneous determination of linagliptin and empagliflozin in their co‑formulated dosage form
      M. RIZK, A. ATTIA, H. MOHAMED*, M. ELSHAHED (*Department of Analytical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt,

      J. Planar Chromatogr. 33, 647-661 (2020). HPTLC of empaglifozin (1) and linagliptin (2) on silica gel with chloroform - methanol - ammonia (25 %) 100:10:1. Quantitative determination by absorbance measurement at 225 nm. The hRF values for (1) and (2) were 31 and 71, respectively. Linearity was between 100 and 5000 ng/zone for (1) and 50 and 2500 ng/zone for (2), respectively. Intermediate precision was below 2 % (n=3). The LOD and LOQ were 32 and 97 ng/zone for (1) and 14 and 42 ng/zone for (2), respectively. Average recovery was 100.1 % for (1) and 99.9 % for (2). Comparison with a similar TLC method showed no significant statistical differences.

      Classification: 9, 23e
      127 041
      Simultaneous estimation of azilsartan medoxomil and chlorthalidone by chromatography method using design of experiment and quality risk management based quality by design approach
      P. PRAJAPATI*, S. PATEL, A. MISHRA (*Department of Quality Assurance, Maliba Pharmacy College, Uka Tarsadia University, Tarsadi, Mahuva, Surat, Gujarat 394350, India,

      J. Planar Chromatogr. 33, 631-646 (2020). HPTLC of azilsartan medoxomil (1) and chlorthalidone (2) on silica gel with toluene - methanol - ethyl acetate - formic acid 35:10:5:1. Quantitative determination by absorbance measurement at 241 nm. The hRF values for (1) and (2) were 55 and 36. Linearity was between 800 and 4000 ng/zone for (1) and 250 and 1250 ng/zone for (2), respectively. Intermediate precision was below 2 % (n=3). The LOD and LOQ were 15 and 44 ng/zone for (1) and 10 and 32 ng/zone for (2). Recovery was between 100.8 and 101.7 % for (1) and 99.4 and 101.0 % for (2).

      Classification: 23e, 32a
      126 011
      Quality risk assessment and DoE-based analytical quality by design approach to stability-indicating assay method for acidic degradation kinetic study of apremilast
      P. PRAJAPATI*, H. PATEL, S. SHAH (*Maliba Pharmacy College, Maliba Campus, Uka Tarsadia University, Bardoli, Gujarat 394350, India,

      J. Planar Chromatogr. 33, 231-244 (2020). HPTLC of apremilast on silica gel with toluene - methanol - ethyl acetate 7:2:1. Quantitative determination by absorbance measurement at 241 nm. The hRF value for apremilast was 63. Linearity was between 200 and 1000 ng/zone. Inter-day and intra-day precision were below 1 % (n=3). The LOD and LOQ were 4 and 13 ng, respectively. Recovery rate was between 99.7 and 100.0 %. Apremilast was subjected to acidic, alkaline, oxidative, dry heat, neutral, and photolytic degradation conditions. The method was implemented using a quality risk management and quality by design approach for regulatory requirements.

      Classification: 23e
      106 114
      HPLC, TLC, and first-derivative spectrophotometry stability-indicating methods for the determination of tropisetron in the presence of its acid degradates
      L.S. ABDEL-FATTAH, Z. EL-SHERIF, K.M. KILANI, Dalia A. EL-HADDAD* (*National Organization for Drug Control & Research, 6&7 AboHazem St, Pyramids, P. O. Box 29, Giza, Egypt;

      J. AOAC Int. 93, 1180-1191 (2010). TLC of tropisetron and its acid-induced degradation products on silica gel with methanol - glacial acetic acid 22:3 with chamber saturation for 45 min. Detection under UV light at 254 nm. Quantitative determination by scanning at 285 nm. The hRf values were 44, 84, and 92 for tropisetron and degradates I and II, respectively. Linearity was between 1 and 10 µg/zone. Mean accuracy was 100.2 %. The precision was 0.64 %.The limit of detection and quantification for tropisetron was 0.26 and 0.80 µg/zone, respectively. The intraday and interday precisions were evaluated by assaying freshly prepared samples of tropisetron in triplicate concentrations, i. e. 3, 5, and and 9 µg/zone, resulting in 99.8 %, 100.3 %, and 100.4 %, respectively, for interday precision and 99.7 %, 100.2 %, and 99.7 %, respectively, for intraday precision (with a precision of 0.9 %, 0.6 %, 0.8 % and 0.6 %, 0.4 %, 0.6 %, respectively).

      Classification: 23