Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      131 002
      Bioassay-guided fractionation leads to the detection of cholic acid generated by the rare Thalassomonas sp.
      F. PHEIFFER, Y. K.-H. SCHNEIDER, E. H. HANSEN, J. HAMMER ANDERSEN, J. ISAKSSON, T. BUSCHE, C. RÜCKERT, J. KALINOWSKI, L. van ZYL, Marla TRINDADE* (*Institute for Microbial Biotechnology and Metagenomics, Department of Biotechnology, University of the Western Cape, Bellville, Cape Town, South Africa;

      Marine Drugs 21(1), 2 (2023). Samples were methanol extracts of cultivated marine bacteria Thalassomonas actiniarum, T. viridans and T. haliotis (Colwelliaceae),  as well as cholesterol, cholic acid, and deoxycholic acid as standards. TLC on silica gel with n-hexane – ethyl acetate – methanol – acetic acid 20:20:5:2. After drying at room temperature, visualization by spraying with phosphomolybdic acid (10 % in ethanol) and heating with a heat-gun. For isolation of cholic acid (hRF 80), present in all samples, preparative TLC on silica gel with the same mobile phase, the corresponding band was scraped off with a surgical blade and extracted with methanol overnight. The isolated cholic acid was identified by LC-MS.

      Classification: 13c, 13d
      126 026
      Thin-layer chromatographic separation of a number of bile acids with mobile phases based on surfactants
      N. REPINA, Olga KONOVALOVA*, D. KALININ, D. EDAMENKO (*Department of Chemical Metrology, Kharkiv V.N. Karazin National University, 4 Svobody Sq, Kharkiv 61022, Ukraine,

      J. Planar Chromatogr. 33, 271-279 (2020). Two-dimensional HPTLC of cholic, ursodeoxycholic, chenodeoxycholic, deoxycholic, and lithocholic bile acids on silica gel with 0.0001 M cetylpyridinium chloride at pH 9 with the addition of aliphatic alcohol modifiers 4 % 1-butanol (direction II) and 0.6 % 1-pentanol (direction II). Detection by drying the plate for 2-3 min in the oven at 120 ºC, followed by spraying with 8 % sulfuric acid in ethanol. Qualitative determination under UV light at 365 nm.

      Classification: 13d
      124 038
      Differentiation of various snake bile derived from different genus by high-performance thin-layer chromatography coupled with quadrupole time-of-flight mass spectrometry
      T. ZHENG (Zheng Tian Jiao), X. CHENG (Cheng Xianlong), L. WAN (Wan Linchun), Y. SHI (Shi Yan), F. WEI (Wei Feng)*, S. MA (Ma Shuang Cheng) (*National Institute for Food and Drug Control, 2 Tiantan Xili, Beijing 100050, China)

      J. AOAC Int. 102, 708-713 (2019). TLC of snake bile in 20 species from three families (Elapidae, Colubridae, and Viperidae) on silica gel with xylene – isopropanol – methanol – glacial acetic acid – water 80:40:30:20:3. Detection by spraying with a 10% sulfuric acid ethanol solution, followed by heating at 105 ºC.  Qualitative identification under UV light at 366 nm. TLC coupled with quadrupole–time-of-flight–MS analysis of each zone was used for compound identification and evaluation.

      Classification: 13d
      102 036
      TLC of selected bile acids
      Alina PYKA (Faculty of Pharmacy, Department of Analytical Chemistry, Medical University of Silesia, 4, Jagiellonska Str., 41-200 Sosnowiec, Poland;

      J. Liq. Chromatogr. Relat. Technol. 31, 1373-1385 (2008). TLC of cholic acid, glycocholic acid, glycolithocholic acid, deoxycholic acid, chenodeoxycholic acid, glycodeoxycholic acid, and lithocholic acid on silica gel with concentration zone, prewashed with methanol and dried for 24 h at room temperature, in a saturated chamber. Best separation of the bile acids was achieved with n-hexane - ethyl acetate - methanol - acetic acid 20:20:5:2. Detection by dipping for 15 s in sulfuric acid - methanol 1:19, followed by heating at 90 °C for 20 min provided better results than derivatization by spraying with 10 % phosphomolybdic acid in ethanol. Quantitative determination by absorbance measurement between 190 and 800 nm.

      Classification: 13d
      65 040
      Planar chromatography coupled with secondary ion mass spectrometry
      K.L. BUSCH, (School of Chemistry and Biochemistry, Atlanta, GA 30332, USA)

      J. Planar Chromatogr. 2, 355-361 (1989). Description of the use of SIMS in the direct analysis of samples separated by TLC (bile acids and diuretics). Discussion of the correct selection of extraction/sputtering solvent, the influences of extraction solvent volume and primary ion beam parameters.

      Classification: 4e, 13d
      97 029
      Optimization of TLC detection by phosphomolybdic acid staining for robust quantification of cholesterol and bile acids
      P. K. ZARZYCKI*, M. A. BARTOSUK, A. I. RADZIWON (Laboratory of Toxicology, Department of Environmental Biology, Technical University of Koszalin, Koszalin, Poland.

      J. Planar Chromatogr. 19, 52-57 (2006). TLC and HPTLC of cholesterol, cholic and lithocholic acid, and taurodeoxycholic acid sodium salt on silica gel with methanol - dichloromethane 1:4, and on RP18 with methanol - water 4:1 with chamber saturation. Detection by spraying with phosphomolybdic acid solution and placing the plates in a gravity convection oven. The plates were heated to different temperatures from 40 to 120 °C for different periods of time (from 2 to 40 min). Best conditions for sensitive and robust detection on silica gel and RP18 were low derivatization temperatures around 60 °C and long heating times of more than 15 min.

      Classification: 13d
      106 077
      Estimation of chromatographic lipophilicity of bile acids and their derivatives by reversed-phase thin layer chromatography
      C. ONISOR, M. POSA, S. KEVRESAN, K. KUHAJDA, C. SARBU* (*Babes-Bolyai University, Faculty of Chemistry and Chemical Engineering, Arany Janos 11, 400028 Cluj-Napoca, Romania,

      J. Sep. Sci. 33, 3110-3118 (2010). HPTLC of bile acids and their derivatives on 1) RP-18, 2) RP-18W and 3) cyano phase with methanol - water mixtures. The volume fraction of organic solvent in the mobile phase ranged from 70-90 % for (1), 50-70 % for (2) and 45-65 % for (3). Detection by spraying with a solution of manganese chloride in sulfuric acid, followed by heating at 100-120 °C for 10 min. Quantification by absorbance measurement at 254 nm and 365 nm.

      Classification: 13d
      65 077
      (Study of biles from animal sources by thin-layer chromatography
      S. NI (Ni Sufang), N. CHEN (Chen Ningning), W. FENG (Feng Wenli), (Liaoning Inst. Mater. Med., Shengyang, P.R. China)

      J. Shenyang Pharm. Coll. (Shenyang Yaoxueyuan Xuebao) 6, 197-198 (1989). TLC of bile components on silica with isopentanol - acetic acid - water 18:5:3. Identification by comparing the Rf values with those of standards.

      Classification: 11a, 13d