J. Food Hyg. Soc. of Jap. 34, 512-516 (1993). Description of reverse-phase TLC/FABMS method incorporating an analyte condensation technique for the identification of 12 coal tar dyes, using the magic bullet matrix (a 3:1 dithiothereitol-dithio-erythritol mixture). TLC of xanthene and other dyes on RP-18 with MEK - methanol - 5% aqueous sodium sulfate solution 1:1:1, and 2) methanol - acetonitrile - 5% aqueous sodium detection limit 150-fold with good reproducibility by using the condensation technique.

Anal. Chem. 67, 1805-1814 (1995). Presentation of a direct coupling protocol of TLC with matrix-assisted laser desorption ionization (MALDI) MS, including analyte extraction from TLC plate, its transport to the surface following matrix deposition and crystallization. Optimization of the extraction procedure. Evaluation of the MALDI matrices for use with silica and cellulose TLC plate. Discussion of the detection limits, the influence of ninhydrin on spectral quality, and suitability of TLC/MALDI method for direct TLC imaging.

J. Planar Chromatogr. 9, 84-91 (1996). Review of the use of tandem mass spectrometry (MS-MS) in combination with planar chromatography (TLC or HPTLC). Examples of the use of the technique with a wide range of synthetic compounds (drugs, plasticizers) and natural products (steroids, glycolipids) are provided. Ionization techniques for performing TLC-MS are described and critically appraised and practical aspects of the hyphenation of TLC and mass spectrometry are considered. Discussion of the advantages of MS-MS over simple MS techniques.

Talanta 42, 1553-1557 (1995). TLC on RP-18 with methanol - water 1:1, 1:3, 1:5. Analysis of amino acids that form colored compounds with reagents such as ninhydrin by spectrophotometry.

seed oils. J. High Resol. Chromatogr. 20, 315-320 (1997). TLC of oils and fatty acid methyl esters (FAME) on silica gel with hexane - ether 7:3 or 8:2. Detection by spraying with phosphomolybdic acid (5% in ethanol) and heating at 100°C. Preparative TLC on silica gel impregnated with 100% silver nitrate in acetonitrile, with hexane - ether - acetic acid 90:9:1. Detection by spraying with 2,7-dichlorofluorescein and under UV. Analysis by GLC after elution. Identification by GC/MS and IR.

GIT Fachz. Lab. 1, 14-18 (1999). TLC of hydroxybenzenes (pyrocatechol, resorcinol, phloroglucinol, hydroquinone, and pyrogallol) on conventional silica gel and specific Raman-TLC plates (coated with spherical silica gel) with toluene - methanol - acetic acid 45:16:4 in a saturated chamber. The spectra obtained by Raman spectroscopy enabled the use of data banks for the identification of substances. Typical detection limits are in the low microgram region per application.

J. Chinese Trad. & Herb. Drugs (Zhongcaoyao) 32 (4), 312-314 (2001). TLC on silica gel with chloroform - methanol - water 65:30:10. Detection by spraying with 10% sulfuric acid in ethanol and heating at 1058C for 5 min. Quantitation by spectrophotometry.

J. Planar Chromatogr. 17, 398-403 (2004). Review divided into several sections: ,Summaries’ contains a review of some recent research results in TLC-MS and PC-MS (use of a diode IR laser to desorb samples from a thin-layer chromatogram, with ionization of the desorbed gaseous molecules via a corona discharge; description of an interface between TLC and an electrospray ionization (ESI) mass spectrometer; ,on spot’ matrix-assisted laser desorption ionization (MALDI) mass spectrometry for TLC-MS); in ,Assessments and perspectives’ new results are detailed, precedent and new instrumental developments are previewed; in the section ,Interconnections’ synergies between mass spectrometry and different approaches to planar separations are explored. Finally, in ,Forecasts’ expectations and future developments, in addition to recent techniques, are described. 11 references.