Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      90 015
      TLC-TOF SIMS monitoring of zinc complex origin - carboxylate ligand movement
      A. ORINAK*, C. CRONE, A. BENNINGHOVEN, N. BUSCHMANN, R. ORINAKOVA, H.F. ARLINGHAUS, M. JUSTINOVA, (*Inst. of Chem. Sci., Univ. of P. J. Safarik, Moyzesova 11, 041 54 Kosice, Slovak Republic)

      J. Planar Chromatogr. 15, 286-288 (2002). To characterize the stability and retention behavior of zinc carboxylato mixed-ligand complexes movement of the carboxylate ligand has been monitored by TLC coupled with time-of -flight secondary-ion mass spectrometry (TLC-TOF SIMS). TLC of zinc carboxylato mixed-ligand complexes on RP-18, prewashed with methanol, with methanol - water 2:3. After development the layers were coated with silver, from the vapor state, and the analytes were eluted with a strongly polar mobile phase to a target channel.

      Keywords:
      Classification: 4e
      96 030
      The potential of BioArena in the study of the formaldehydome
      E. TYIHAK*, A. MORICZ, P.G. OTT, G. KATAY, Z. KIRALY-VEGHELY (Plant Protection Institute, Hungarian Academy oF Sciences, Budapest, Herman O. Str. 15, 1022 Budapest, Hungary)

      J. Planar Chromatogr. 18, 67-72 (2005). TLC of trans-resveratrol (trans-3,5-dihydroxystilbene), semicarbazide and dimedone (as standards) on silica gel using different mobile phases; OPLC on silica gel with chloroform - methanol 10:1. After drying bioautographic detection by immersion in the bacterial suspension of Pseudomonas savastanoi for 25 s. Visualization with MTT either after a short draining period or after overnight incubation.

      Keywords:
      Classification: 4e, 5b, 17a
      103 018
      The Use of Thin-Layer Chromatography with Direct Bioautography for Antimicrobial Analysis
      Irena CHOMA (Department of Chromatographic Methods, M. Curie-Sklodowska University, Lublin, Poland)

      LC-GC Europe 18, 482-488 (2005). Contact Bioautography: Antimicrobials diffusion from a TLC plate to an inoculated agar plate.The chromatogram is placed face down onto the inoculated agar layer and left for some minutes or hours for diffusion. After removing the plate the inhibition zones are observed on the agar surface in the places where the spots of antimicrobials are stuck to the agar. The method resembles a disk assay. Immersion Bioautography: The chromatogram is covered with a molten, seeded agar medium. After solidification, incubation and staining (usually with tetrazolium dye) the inhibition or growth bands are visualized. Direct Bioautography: A developed plate is dipped in the suspension of microorganisms growing in a suitable broth or this suspension is sprayed onto the plate. The plate is incubated and microorganisms grow directly on it. It can be performed with Photobacterium phosphoreum (Vibrio fischeri) suspension. Bioautography systems and coupling possibilities are presented.

      Classification: 4e
      104 009
      Direct quantitative bioanalysis of drugs in dried blood spot samples using a thin-layer chromatography mass spectrometer interface
      P. ABU-RABIE*, N. SPOONER (*PreClinical Development Drug Metabolism and Pharmacokinetics, GlaxoSmithKline Research and Development, Park Road, Ware, Hertfordshire, SG12 ODP, United Kingdom; Paul.2.Abu-Rabie@gsk.com)

      Anal. Chem. 81, 10275-10284 (2009). Direct quantitative bioanalysis of drugs from dried blood spot samples using a TLC-MS interface with or without HPLC separation. The method gave acceptable sensitivity, linearity, accuracy, and precision data for bioanalytical validations. The direct elution technique was shown to increase assay sensitivity for a range of analytes. Investigations were performed to optimize extraction time, minimize sample-to-sample carry-over, and compare chromatographic performance. On the basis of this preliminary assessment, it has been demonstrated that this TLC-MS interface has the potential to be an effective tool for the direct analysis of drugs in dried blood samples at physiologically relevant concentrations.

      Classification: 4e
      107 031
      TLC/HPTLC-ELSD-MS coupling
      F. BRETIN, F. MAQUIN* (*Sanofi-Aventis, Centre de Recherche, 13 quii Jules Guesde, 94403 Vitry-sur-Seine, France, francis-maquin@sanofi-aventis.com)

      CBS 105, 2-4 (2010). TLC and HPTLC of reaction samples from small molecule lead development, on silica gel with mixtures of methanol and dichloromethane/ethyl acetate or ethyl acetate and heptane/cyclohexane (ratios depending on the compound mixtures). Detection with primuline or berberine reagent. Direct elution into the MS with the TLC-MS interface. Substances not detected by DAD can successfully be measured by ELSD detection coupled to TLC.

      Classification: 4e
      112 048
      TLC-direct bioautography for determination of antibacterial activity of Artemisia adamsii essential oil
      G. HORVATH, K. ACS (*University of Pécs, Medical School, Department of Pharmacognosy, Hungary, gyorgyi.horvath@aok.pte.hu)

      J. AOAC Int. 96, 1209-1213 (2013). TLC of thujone (1) and 1,8-cineole (2) in the leaves of Artemisia adamsii essential oil on silica gel with toluene - ethyl acetate 93:7. Detection by dipping into vanillin - sulfuric acid reagent, followed by heating at 90 ºC for 3 min. The hRf values for (1) and (2) were 56 and 45. Bioautography by dipping into S. aureus suspension for 10 s. After drying for 2 min followed by incubation at 37 ºC for 17 h the plates were dipped in an aqueous solution of MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide 50 mg/80 mL) for 10 s and incubated at 37°C for 2 h. Inhibition zones appeared as pale yellowish zones against blue background.

      Classification: 4e, 15a
      117 005
      Biological desorption electrospray ionization mass spectrometry (DESI MS) – unequivocal role of crucial ionization factors, solvent system and substrates
      M. MANIKANDAN, Z. KAZIBWE, N. HASAN, A. DEENADAYALAN, J. GOPAL, T. PRADEEP, S. CHUN* (*Department of Bioresource and Food Science, Konkuk University, Seoul 143-701, South Korea, scchun@konkuk.ac.kr)

      Trends Anal. Chem. 78, 109-119 (2016). Review on the application of desorption electrospray ionization mass spectrometry (DESI-MS) for the analysis of biological samples. The review described different substrates in DESI-MS of plant, animal and human samples, including polytetrafluoroethylene/TLC surfaces. A comprehensive list of surfaces and solvents for the analysis of molecules such as salvinorin, divinatorin, metabolites from strawberries, potatoes, among others were described.

      Classification: 1, 4e
      119 026
      Five new triterpenoid saponins from the rhizomes of Panacis majoris and their antiplatelet aggregation activity
      M. LI (Li Min), F. LIU (Liu Fen), Y. JIN (Jin Yong-Ri), X. WANG (Wang Xiao-Zhong), Q. WU (Wu Qian), Y. LIU (Liu Ying), X. LI (Li Xu-Wen)* (*College of Chemistry, Jilin University, Changchun, China; xwli@jlu.edu.cn)

      Planta Medica 83(03/04), 351-357 (2017). Acid hydrolysis of five new dammarane-type saponosides extracted from Panax japonicus var. major rhizomes for 5 h in methanol – HCl 1:1 in sealed capillary at 80°C, then TLC on silica gel with n-butanol – acetic acid – water 5:1:4 (upper phase) and with chloroform – methanol – water 16:8:1. After derivatization with aniline phthalic acid reagent, sugar moieties were identified as glucose units by comparison to standards. Note that in the title, by ignorance of the Latin grammar, the authors wrote “Panacis majoris” instead of the nominative “Panax major”. In the names of the compounds, the –ane or –ene ending was often also omitted.

      Classification: 4e, 6, 9, 14, 32e