Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
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  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. The saved items can be printed to PDF using the print function of your web browser.

      Direct bioautography hyphenated to direct analysis in real time mass spectrometry: Chromatographic separation, bioassay and mass spectra, all in the same sample run
      T. T. HÄBE, Maryam JAMSHIDI-AIDJI, Jennifer MACHO, Gertrud E. MORLOCK* (*Chair of Food Sci., Inst. of Nutrit. Sci., and Interdiscipl. Res. Center (iFZ), Justus Liebig Univ. Giessen, Heinrich-Buff-Ring 26-32, 35392, Giessen, Germany, Gertrud.Morlock@uni-giessen.de)

      J. Chromatogr. A 1568, 188-196 (2018). Application of an advantageous combination, the desorption-based direct analysis in real time mass spectrometry (DART-MS) immediately after direct bioautography (DB), i.e., in the presence of microorganisms, bioassay medium and substrate reagent. The method offers a straightforward and efficient mass spectrometric detection of bioactive analytes within the bioautogram. It discriminated microorganism cells and highly polar bioassay medium ingredients which could otherwise stress the MS system. Investigation of DB-DART-MS for bioactive compounds in cosmetics using the Bacillus subtilis and Aliivibrio fischeri bioassays for detection of Gram-positive and Gram-negative antimicrobials, respectively, and the planar yeast estrogen screen for detection of estrogen-effective compounds. Study of the influences of three different bioassay matrices on the analyte response and DB-DART-MS performance on different layers (NP and RP) on the example of parabens in hand creams. Ion suppression was enhanced with increasing culture medium complexity. The mass spectrometric quantification by DB-DART-MS at the ng-level in situ each different bioautogram was verified by comparison to HPTLC-DART-MS. The total paraben content of hand creams 1 and 2 was 0.17–0.20% and 0.30–0.34%, respectively, depending on the method used. It proved that DB-DART-MS is a reliable qantitative bioanalytical hyphenation.

      Keywords: hptlc cosmetics
      Classification: 4e
      Effect-directed profiling of aqueous, fermented plant preparations via high-performance thin-layer chromatography combined with in situ assays and high-resolution mass spectrometry
      Maryam JAMSHIDI-AIDJI, Jennifer MACHO, Margit MUELLER, Gertrud MORLOCK* (*Institute of Nutritional Science, Interdisciplinary Research Center (IFZ), Justus Liebig University Giessen, Heinrich-Buff-Ring 26–32, 35392 Giessen, Germany, Gertrud.Morlock@uni-giessen.de )

      J. Liq. Chromatogr. Relat. Technol. 42, 266-273 (2019). HPTLC of aqueous, fermented plant preparations from Chamomilla recutita L. (1), Allium cepa L. (2), Equisetum arvense L. (3) and Hamamelis virginiana L. (4) of different harvest years on silica gel with ethyl acetate - toluene - formic acid - water 16:4:3:2. The method was combined with effect-directed analysis (EDA) and high-resolution mass spectrometry (HRMS). For α-/β-glucosidase assays, the plate was sprayed with 2 mL substrate solution (60 mg 2-naphthyl-α-D-glucopyranoside or 2-naphthyl-β-D-glucopyranoside in 50 mL ethanol), then sprayed with 1 mL sodium acetate buffer and 2 mL enzyme solution (500 units α-glucosidase), followed by incubation at 37 ºC for 10 min. Analysis of multi-potent compounds was also performed using the 2,2-diphenyl-1-picrylhydrazyl reagent and Gram-positive Bacillus subtilis assays, followed by recording of elution head-based HPTLC-ESI-HRMS spectra. 

       

      Classification: 4e
      Diterpene lipo-alkaloids with selective activities on cardiac K+ channels
      T. KISS, B. BORCSA, P. ORVOS, L. TÁLOSI, J. HOHMANN, D. CSUPOR* (*Department of Pharmacognosy, Faculty of Pharmacy, University of Szeged, Szeged, Hungary; csupor.dezso@pharmacognosy.hu)

      Planta Med. 83(17), 1321-1328 (2017). Benzoyl-aconine esters (lipo-alkaloids) produced by transesterification of aconitine (isolated from Aconitum sp.) with long-chain fatty acids were purified by a multistep chromatographic method, including cyclodextrane gel filtration chromatography, centrifugal planar chromatography on aluminium oxide layer using cyclohexane – chloroform – methanol 70:30:1 followed by 70:30:3 and/or preparative thin-layer chromatography on aluminium oxide layer with toluene – acetone – ethanol – concentrated ammonia 70:40:10:3.

      Classification: 32e, 22, 11a, 4d, 4e
      Diterpene lipo-alkaloids with selective activities on cardiac K+ channels
      T. KISS, B. BORCSA, P. ORVOS, L. TÁLOSI, J. HOHMANN, D. CSUPOR* (*Department of Pharmacognosy, Faculty of Pharmacy, University of Szeged, Szeged, Hungary; csupor.dezso@pharmacognosy.hu)

      Planta Med. 83(17), 1321-1328 (2017). Benzoyl-aconine esters (lipo-alkaloids) produced by transesterification of aconitine (isolated from Aconitum sp.) with long-chain fatty acids were purified by a multistep chromatographic method, including cyclodextrane gel filtration chromatography, centrifugal planar chromatography on aluminium oxide layer using cyclohexane – chloroform – methanol 70:30:1 followed by 70:30:3 and/or preparative thin-layer chromatography on aluminium oxide layer with toluene – acetone – ethanol – concentrated ammonia 70:40:10:3.

      Classification: 32e, 22, 11a, 4d, 4e
      Solvent front position extraction procedure for preparation of biological samples with coccidiostats for Liquid Chromatography–Tandem Mass Spectrometry determination
      Anna TUREK*, M. RYBICKI, A. GIERACH, W. KOROL, T. DZIDO (*Medical University of Lublin, Department of Physical Chemistry, ul. Chodźki 4a, 20-093 Lublin, Poland, anna.klimek@umlub.pl)

      J. Planar Chromatogr. 32, 41-46 (2019). HPTLC of the five coccidiostats monensin (1), narasin (2), nigericin (3), robenidine (4) and salinomycin (5) on silica gel with at least two developments with methanol. After evaporation of the solvent, a TLC–MS interface was used for solvent front position extraction (SFPE) and further analysis by liquid chromatography–tandem mass spectrometry (LC–MS/MS). 
       

      Classification: 4d
      53 021
      Computer-controlled evaluation in TLC/HPTLC
      S. EBEL, J. HOCKE, E. GEITZ

      Proceedings of Sino/ West German Symposium on Chromatography, Science Press,. Beijing, China 563-601 (1983). Using computer controlled TLC photometers, the whole domaine and flexibility of this analytical method can be used in a more accurate way.

      Keywords:
      Classification: 4
      62 039
      Constantly operating thin-layer chromatography
      D. ROGERS, (Mays Lauding, New Jersey, USA)

      Amer. Lab. 19, 23-25 (1987). Description of the advantages of constantly operating TLC over conventional TLC, column chromatography, or free flow analysis. Discussion of several contrasting views on the possibility of automating TLC, stressing on its significant increases in throughput. Some consideration on the chromatographic parameters, and instrumental parameters of constantly operating TLC.

      Keywords:
      Classification: 4
      55 082
      Circular thin-layer chromatography of quaternary alkaloids
      A. BAERHEIM SWENDSEN, A. Van KEPIPEN-VERLEUN, R. VERPOORTE

      Quaternary protoberberine alkaloids in plant material. J. Chromatogr. 291, 389-391 (1984). Circular TLC of quaternary alkaloids from jatrorrhiza palmata on silica with isopropanol - 1 M ammonium carbonate-dioxane 1551. Detection by UV 254 nm. Also PLC. Solvent system suitable for other protoberberine-type alkaloids. Recommended method for protoberberine alkaloid separation.

      Keywords:
      Classification: 22, 4a