Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      74 022
      Application of trifluoroacetic anhydride-sodium iodide reagent for selective detection in thin-layer chromatography IV
      A. KOTYNSKI, Z.H. KUDZIN*, (*Dept. Org. Chem., Univ. Lodz, Narutowcza 68, Lodz 90-136, Poland)

      Thin-layer chromatographic differentiation of nitrones, nitroxide radicals and nitroso amines in mixtures. J. Chromatogr. 663, 127-131 (1994). TLC of title compounds on silica with chloroform (or methanol) - acetone 4:1. Detection by spraying with sodium iodide and subsequently with trifluoroacetic anhydride-sodium iodide reagent. Brown spots appear on white background, stable for more than 20 min.

      Classification: 3e, 17
      78 042
      Effect of fluorescence intensifiers on the fluorodensitometric determination of flavones and flavonols after detection with diphenylboric acid 2-aminoethyl ester
      TH. KARTNIG*, I. GOEBEL, (*Inst. Pharm., Univ. Graz, UniversitÑtsplatz 411, A-8010 Graz, Austria)

      J. Chromatogr. A, 740, 99-107 (1996). TLC on silica with 1) toluene - ethyl formiate - formic acid 5:4:1, and 2) ethyl acetate - formic acid - water 20:2:1. Detection by dipping into diphenylboric acid 2-aminoethyl ester solution, and by fluorodensitometry. Investigation of the effect of different substances on the intensity and stability of the fluorescence. Comments on the procedure for measurement, and discussion of the correlation between fluorescence and molecular structure.

      Classification: 3e, 8a
      88 018
      A new chromogenic spray reagent for the detection and identification of monocrotophos
      V.B. PATIL, M.V. GARAD*, (Reg. For. Sci. Lab., State of Maharashtra, Cantonment, Aurangabad-431 002, India)

      J. Planar Chromatogr. 14, 210-212 (2001). HPTLC of monocrotophos and other organophosphorus insecticides (malathion, ethyl parathion, methylparathion, fenitrothion fenthion, phorate, dimethoate, phosphamidon, dichlorvos), organochlorine insecticides, carbamate insecticides, pyrethroid insecticides on silica gel in a pre-saturated chamber with chloroform - acetone 7:3. After drying the plate is sprayed with a 20% anhydrous sodium carbonate solution then with 0.5% chloranil (in acetone) reagent. The reagent is selective for monocrotophos among other insecticides.

      Keywords:
      Classification: 3e, 29b
      103 016
      2,4,6-triphenylpyrylium cations as derivatization reagents for sulfide ions detection in TLC
      R. ZAKRZEWSKI*, W. CIESIELSKI, A. ULANOWSKA, R. MARTINEZ (*Department of Instrumental Analysis, University of Lodz, Lodz, Poland, robzak@chemul.uni.lodz.pl)

      Phosphorus, Sulfur Silicon Relat. Elem. 184, 1139-1148 (2009). The new TLC system for sulfide ions detection is based on the use of 2,4,6-triphenylpyrylium salts as pre-chromatographic derivatization reagents. The cations L1 (2,4,6-triphenylpyrylium) or LN1 (4-[p-(N,N-dimethylamino) phenyl]-2,6-diphenylpyrylium) were used in the derivatization reactions in a tube or directly on the TLC plate before the developing step. TLC of L1 on silica gel with methanol – dichloromethane 1:5. TLC of LN1 on cellulose with phosphoric buffer (pH 6.0) – acetonitrile – 1,4-dioxane 4:2:1. The detection procedure allows selective and sensitive detection for sulfide anions at several dozen pmol/spot.

      Classification: 3e
      122 020
      All on one high-performance thin-layer chromatography plate
      I. YÜCE, Gertrud E. MORLOCK* (*Chair of Food Sci., Inst. of Nutrit. Sci., Interdiscipl. Res. Center (IFZ), Justus Liebig Univ. Giessen, Heinrich-Buff-Ring 26-32, 35392, Giessen, Germany, Gertrud.Morlock@uni-giessen.de)

      J. Chromatogr. A, 1572, 145-151 (2018). Introduction of on-surface reactions as a new strategy for rapid structure elucidation. This was illustrated by a miniaturized on-surface synthesis-guided identification of two new degradation products (impurities) occurring in a pharmaceutical formulation of the anti-cancer drug ifosfamide, especially in the presence of urea. The respective reagents were applied in the nanomole scale accurately and automated on a HPTLC silica gel plate. After a fast reaction in the start zone, the plate was developed, followed by online elution to high-resolution MS, whereby the on-surface reaction highlighted the impurities. As proof of concept and for benchmarking, it was compared to a reaction mixture obtained from conventional preparative synthesis in a round-bottom flask as well as to different formulations. Image evaluation was performed by videodensitometry. Discussion of the advantages such as: 1) the combination of all relevant steps on one HPTLC plate and its resulting efficiency made surface synthesis on chromatographic phases an optimal tool for signal highlighting in MS, and thus for the assignment of impurities in drugs; 2) the miniaturization of the chemistry process scale down to the μg-level per synthesis (in total 30-60 μg chemicals/reaction), setting a new state-of-the-art standard; 3) the contribution to a greener chemistry by reducing the consumption of chemicals and enhancing the analytical efficiency, when adapted for the quality control of any other chemical product.

      Classification: 3e, 4e, 32c
      59 188
      Direct fluorescence detection of non-steroidal anti-inflammatory agents separated by TLC with 9-isothiocyanatoacridine derivatives
      C. SARBU*, C. MARUTOIU, M. VLASSA, (* Polytech. Inst., Fac. Mech. Eng., 3400 Clay-Napoca, Romania)

      Chromatographia 21, 599-600 (1986). TLC of non-steroidal anti-inflammatory agents on silica with chloroform - methanol 25 % NH3 80:15:5. Detection by spraying with 0.1 % 9-isothiocyanotoacridine derivatives in dichloromethane or benzene and irradiating with UV 254 and 366 nm. Detection limit 0.1 mg.

      Classification: 3e, 32a
      66 030
      Fast Black K salt
      I. OJANPERÄ*, K. WÄHÄLÄ, T.A. HASE, (*Dep. Foren. Med., Univ. Helsinki, Kytösuontie II, SG-00300 Helsinki, Finland)

      Analyst 115, 263-267 (1990). Evaluation of diazonium reagent Fast Black K salt for visualization of amines and phenols on silica plates. Differentiation between aliphatic primary and secondary amines by color. Determination of the structures of colored reaction products. Detection limit 0.05 – 0.5 µg for various chromatographed drug substances.

      Keywords:
      Classification: 3e, 17a
      74 027
      (Densitometric detection of fluorescence enhanced by using a transparent polymer film in TLC
      K. SUGATA, K. NAGASHIMA, M. KAMAYA, E. ISHII, (Fac. Eng., Kogakuin Univ., Tokyo, Japan 160)

      Bunseki Kagaku (Jap. Anal. Chem.) 42, T143-146 (1993). Description of a method for fluorescence enhancement of spots on TLC plate by wrapping a silica plate with a transparent poly(vinylidene chloride) film just after development, and vaporizing the solvent of the plate with hot air for 15 min. The detection limits of N-dansyldiethylamine, 15 pmol per spot. Application of the method to other plates, such as RP-8 or RP-18, as well as to different solvents, such as benzene, chloroform, and 1,2-dichloroethane, and to the fluorescence compounds such as N-dansylamide, N-dansylhexylamine and dansylglycine.

      Keywords:
      Classification: 3e