J. Planar Chromatogr. 6, 296-299 (1993). Integration of four computer-assisted methods (the monofactor optimization system (MOS); the multicomponent solvent optimization system (MSOS); the difactor optimization system (DOS); and the stepwise gradient optimization (SGOS)) for optimizing HPTLC separation in order to produce the optimization system of TLC (OS T), resulting in a method development strategy which obtains simple solutions for simple separation problems and reserves the more complex solutions for difficult separations.

Proc. 9th Internat. Symp. Instr. Chromatogr., Interlaken, April 9.-11., 337-339 (1997). Prediction of retention data using multiple development and circular techniques from a single development.

J. Planar Chromatogr. b, 178-182 (2001). Evaluation of molecular interactions in liquid adsorption chromatography with mixed mobile phases. Two equations based on different retention mechanism models were verified experimentally. TLC on silica gel; development in horizontal chambers with cyclohexane - carbon tetrachloride, cyclohexane - ethylene chloride, n-heptane - ethylene chloride, and n-heptane - acetone.

2: Comparison of some parameters in OPLC and TLC. J. Planar Chromatogr. 6, 256-258 (1993). Investigation of the linearity of the calibration graph, the limits of detection and quantification and the precision of the data of an OPLC purity test during the development of chromatograms at different flow rates. The best results (lowest LOD and LOQ as well as the best precision) were obtained by OPLC when eluting with the optimum linear velocity. Quantification by densitometry at 237 nm.

Proc. Intern. Symp. on Planar Separations, Planar Chromatography 2001, pp. 91-101. HPTLC of sodium glutamate on silica gel. Quantitative TLC is considered as a typical separation technique where evaluation of uncertainty can be done with seriously planned validation. The contributions of sources calculated according to guidelines are so small that their effects on the final results are negligible.

J. of Chromatogr. A 1258, 94-100 (2012). Study of seven angiotensin-converting enzyme (ACE) inhibitors (enalapril, quinapril, fosinopril, lisinopril, cilazapril, ramipril, benazepril) to evaluate the correlation between their absorption and UHPLC–MS and RP-TLC hydrophobicity data (f0 or C0 parameters, respectively). Their absorption values were in the range of 25–60 % and calculated KOWWIN logP values ranged from -0.94 to 6.61. In order to obtain reliable correlation (r2 = 0.7208) between absorption and ACE inhibitors lipophilicity the solubility data (logS) must be considered, as independent variable, simultaneously with KOWWIN logP. Study of the relationships between literature available and absorption data predicted by multiple linear regression (MLR) using logS values besides chromatographically obtained hydrophobicity parameters C0 (r2 = 0.6424) or f0 (r2 = 0.6762) indicates that these parameters could be used in ACE inhibitors absorption evaluation. The UHPLC–MS method provides the direct application of experimentally obtained f0 values. Mathematical conversion of C0 parameters to logC0 values was necessary based on requisite for probability value of regression analysis (P < 0.05) for better MLR correlation of ACE inhibitors absorption with C0 parameters (RP-TLC) and logS. Definition of the accordance and differences between hydrophobicity parameters obtained by UHPLC–MS and RP-TLC.

Chromatographia 18, 37-40 (1984). The effects of different binary solvents on the retsntion behaviour of some steroids in TLC on alumina were studied. The slope of the linear relationship between the retention constant of the steroid and the logarithm of the volume fraction of the polar component in the binary solvent mixture depends predominantly on the diluent. Linear relationships between the axis intercepts and slopes of particular steroids exists for all chromatographic systems examined. TLC on alumina with different solvents, e.g. cyclohexane, benzene, chloroform or ether, ethyl acetate, MEK, etc.

J. Chromatogr. 290, 75-81 (1984). Method for constructing overlapping resolution maps for thin-layer chromatography. The axes of the maps are time, length and binary solvent composition. These maps can be used to identify sets of compounds within a mixture such that each set is fully separated under appropriate conditions. The separation of a mixture of fifteen steroids is described.