Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      83 012
      Determination of lipophilicity of some non-steroidal anti-inflammatory agents and their relationships by using principal component analysis based on thin-layer chromatographic retention data
      C. SARBU*, S. TODOR, (*"Babes-Bolyai" Univ., Fac. Chem. & Chem. Eng., Arany Janos II, 3400 Cluj-Napoca, Romania)

      J. Chromatogr. A 822, 263-269 (1998). Determination of the relative lipophilicity of ten non-steroidal anti-inflammatory agents by reversed-phase TLC using different plates and water - methanol mixtures as eluents. Investigation of the retention behavior of the compounds, their Rm values decrease linearly with increasing concentration of methanol in the eluents. Estimation and comparison of lipophilicity of the "congeneric lipophilicity chart".

      Keywords:
      Classification: 2d
      89 007
      (Determination of formation constants for the inclusion complexes between emodin, aloe-emodin and cyclodextrins by thin-layer chromatography
      X. WANG (Wang Xiaoping), M. MA (Ma Maixia), SH. SHUANG (Shuang Shaomin), Y. ZHANG (Zhang Yong), J. ZHANG (Zhang Jinghao)*, (*Dept. Chem., Shanxi Univ., Taiyuan 030006, P.R. China)

      Chinese Anal. Chem. (Fenxi Huaxue) 30 (1), 38-41 (2002). TLC on polyamide with cyclodextrins (0-8 x 10-3 mol/L) as mobile phase and NH3(H2O-NH4Cl, pH 9.7 as buffer. Detection under UV. Investigation of the interaction between emodin, aloe-emodin and six cyclodextrins. Comparison of the inclusion capacity of different cyclodextrins. Calculation of the thermodynamic parameters of the interaction. Discussion of use of this interaction to modify the biological properties of emodin and aloe-emodin.

      Keywords:
      Classification: 2d, 32
      97 165
      Application of Thin-Layer Chromatography to investigate oscillatory instability of the selected profen enantiomers in dichloromethane
      M. SAJEWICZ*, R. PIETKA, A. PIENAK, T. KOWALSKA (*Institute of Chemistry, Silesian University, 9 Szkolna Street, 40-006 Katowice, Poland)

      J. Chromatogr. Sci. 43 (10), 542-548 (2005). The usefulness of TLC as an efficient measuring technique in the studies of oscillatory trans-enantiomerization of profens from the S to the R configuration (and vice versa) during their storage as 70 % ethanol solutions is demonstrated in the literature. S-(+)-ibuprofen, S-(+)-naproxen, and S,R-(±)-2-phenylpropionic acid are utilized as the test profens. It is proven possible to show oscillatory instability with the racemic S,R-(±)-2-phenylpropionic acid also. Correctness of the TLC assessment is successfully confirmed by means of polarimetry. Upon these preliminary results, it is concluded that the most probable mechanism might embrace the keto-enol tautomerism because of a convenient migration of the proton from one moiety of the profen molecule to another in an aqueous medium. To indirectly verify this hypothesis, profens are stored in dichloromethane, deliberately hampering their ability to dissociate and to re-structure. It is shown that the non-aqueous solvent considerably suppresses, although they do not completely eradicate, the oscillatory trans-enantiomerization of profens. In view of these findings, the reports which claim a predominant therapeutic potential of the respective S-profens become less convincing and certainly need reconsideration.

      Classification: 2d, 38
      68 015
      Computer-aided optimization of liquid-solid systems in TLC - 2) Comparison of selectivity for various silica-diluent + modifier systems
      M. MATYSKA*, E. SOCZEWINSKI, (*Dept. of Inorg. & Anal. Chem., Medical Acad., ul. Staszica 5, 20-081 Lublin, Poland)

      J. Planar Chromatogr. 3, 264-268 (1990). Comparison of various diluent + modifier - silica systems for 57 solutes by graphical methods; i.e. RM vs. eluent spectra plotted on the basis of equieluotropic series of RM1 vs. RM2 correlations. The spread of points was largest when the binary eluents differed in both diluent and modifier. The differentiated selectivity characteristics of the diluent - modifier binaries demonstrate good prospects for computer-aided selection of an optimal system for TLC analysis of a given set of compounds from the data base.

      Keywords:
      Classification: 2d, 2e
      70 064
      Retention behavior of closely related coumarins in thin-layer chromatographic preassays for high-performance liquid chromatography according to the „PRISMA“ model
      P. HÄRMÄLÄ, (Pharmacognosy Div., Dept. of Pharm., Univ. of Helsinki, SF-001 70 Helsinki, Finland)

      J. Chromatogr. 593, 329-337 (1992). Study of the retention behavior of 14 closely related coumarins in normal-phase TLC and HPLC with the aim of testing the suitability of TLC as a pre assay of HPLC when the optimization of the mobile phase has been carried out according to the PRISMA system. Measurement of the retention in TLC and HPLC at 37 and 13 selective points, respectively. Two and three dimensional evaluations of capacity factor k' against selectivity points showed similar retention behavior for the coumarins in TLC and HPLC. Discussion of the dependency of k' on the change in solvent strength.

      Keywords:
      Classification: 2e, 8b
      76 012
      Automatic mobile phase optimization, using the “PRISMA” model, for the TLC separation of apolar compounds
      SZ. NYIREDY*, Z. FATER, (*Res. Inst. f. Med. Plants, P. O. Box 11, H-2011 Budakalasz, Hungary)

      J. Planar Chromatogr. 8, 341 - 345 (1995). Description of the vertical and horizontal correlations between the hRf values of apolar compounds and the selectivity points at constant and different solvent strength levels in saturated TLC chambers. - HPTLC of furocoumarins on silica, of anthraquinones on silica CN-phase and of opium alkaloids on NH2 silica with multicomponent solvent systems (dichloromethane, tetrahydrofuran, chloroform, n-hexane; ether, tetrahydrofuran, ethyl acetate, hexane; ethyl acetate, acetone, dichloromethane, hexane, methanol). - Anthraquinone aglycones: rhein, aloe-emodin, emodin, physicon, chrysophanic acid; furocoumarin isomers: bergaptene, iso-bergaptene, shondin, pimpinellin, iso-pimpinellin, xanthotoxin, angelicin, psoralen; opium alkaloids: morphine, codeine, narcotoline, thebaine, papaverine, narcotine. Densitometry at 425 nm (anthraquinones), or 280 nm (opium alkaloids).

      Keywords:
      Classification: 2e
      84 001
      A new mathematical model for the optimization of the mobile phase composition in HPTLC and the comparison with other models
      C. CIMPOIU, L. JANTSCHI, T. HODISAN, (Fac. of Chem. and Chem. Engineering, "Babes-Bolyai" Univ., 11 Arany Janos, 3400 Cluj-Napoca, Romania)

      J. Liq. Chrom. & Rel. Technol. 22, 1429-1441 (1999). Presentation of a new mathematical model for the optimization of the eluent composition used for the separation of a mixture of 1,4-benzodiazepines. HPTLC of 1-chlordiazepoxide, oxazepam, nitrazepam, medazepam and diazepam on silica gel with chloroform - acetone - isopropanol mixtures in different compositions. Quantitation by densitometry in reflectance mode at 254 nm.

      Keywords:
      Classification: 2e
      113 005
      Discrete fourier transform convoluted densitometric peak responses for the determination of methocarbamol in different pharmaceutical mixtures in the presence of its degradation product
      M. RAGAB*, M. KORANY, M. ISSA, H. DAABEES, D. ELKAFRAWY (*Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, University of Alexandria, Alexandria, Egypt, marmed_2001@yahoo.com)

      J. Planar Chromatogr. 27, 1999-2020 (2014). HPTLC of methocarbamol in pharmaceutical mixtures with ibuprofen, paracetamol and diclofenac sodium and in the presence of its degradation product guaifenesin on silica gel with chloroform - methanol 47:3. Quantitative determination by absorbance measurement at 264 nm. A chemometric handling of the TLC peak responses involving the convolution of the derivative curves using 8-points sin x i polynomials, allowed the analysis of different mixtures of methocarbamol with enhancing of the regression parameters.

      Classification: 2f, 32a