J. Chinese Trad. Patent Med. (Zhongchengyao) 23 (1), 20-23 (2001). TLC on silica gel with 1) petroleum ether (60-90°C) - ethyl acetate 50:1, 2) ethyl acetate - formic acid - acetic acid - water 15:1:1:2, 3) chloroform - ethyl acetate - methanol - water 15:40:22:10, 4) ethyl acetate - methanol - water 100:17:13, 5) cyclohexane - ethyl acetate 22:1, 6) toluene - ethyl acetate - formic acid 40:8:1, 7) benzene - acetone 9:1. Detection 1) by spraying with 5% vanillin-sulfuric acid reagent and heating at 110°C, 2) with 5% sulfuric acid in ethanol and heating at 105°C, 3) with 3% AlCl3 and under UV 365 nm, 4) with acetoanhydride - sulfuric acid 9:1 and heating at 110°C, 4) with aceto anhydride - sulfuric acid and heating at 110°C, 5) with 20% perchoric acid and heating at 105°C for 10 min. Identification by finger print technique.

J. Liq. Chrom. Rel. Technol. 27, 1967-1980 (2004). Part of a study originally devoted to investigating lateral interactions of monocarboxylic and a,?-dicarboxylic acids analyzed on a low-activity stationary phase (cellulose powder) with low-polarity monocomponent mobile phases (decalin for monocarboxylic acids and 1,4-dioxan for a,?-dicarboxylic acids). TLC of lauric, myristic, palmitic, 3-phenylpropionic, 2-phenylbutyric, and 4-phenylbutyric acid with decalin and of succinic, adipic, and suberic acid with 1,4-dioxan on cellulose. Detection with an ethanolic solution of bromocresol green. Quantitative determination at 625 nm.

J. Planar Chromatogr. 19, 124-128 (2006). Determination of log P values of 29 biologically active chalcone and cyclic chalcone analogues E-2-(X-benzylidene)-1-indanones and E-2-(X-benzylidene)-1-tetralones by an optimized and validated RP-TLC method. RP-TLC was performed on silanized silica gel with methanol - water 3:2. The experimentally determined log P(TLC) values were compared with the log P values predicted by use of the CLOGP program.

J. Chromatogr. Sci. 53 (2), 312-319 (2015). Investigation of lipophilicity for newly synthesized N-substituted-2-phenylacetamide derivatives by TLC on RP-18 in the presence of one protic (methanol) and one aprotic solvent (acetonitrile) followed by mathematical evaluation using different software packages. Establishment of the dependences between the partition coefficient, log P as the standard measure of lipophilicity and the alternative lipophilic parameters using the retention chromatographic constant RM0 and m values (the intercept and the slope of the linear dependence between volume fractions of the organic solvent and the retention parameters obtained experimentally by TLC), employing linear regression analysis and multivariate methods, cluster analysis (CA) and principal component analysis (PCA). All applied methods gave approximately similar results. Although there is a linear dependence between the two chromatographic parameters RM0 and m, only RM0 shows suitable similarity with the standard measure of lipophilicity of the investigated N-substituted-2-phenylacetamide derivatives at the given conditions. This proves that the chromatographic retention constant, RM0, obtained by reversed phase TLC could be successfully used for the description of lipophilicity of the compounds. The results confirmed that the applied linear regression analysis and the multivariate analysis (CA and PCA) have the ability to compare lipophilic parameters of the investigated phenylacetamide derivatives obtained in different ways.

Anal. Letters 21, 1075-1084 (1988). TLC on silica impregnated with metal salts with a) chloroform - butyl acetate 10:5 and b) chloroform - ethyl acetate 25:2. Detection by exposing to iodine vapor. Determination of the partition coefficients and the correlation with Rf values.

J. Planar Chromatogr. 3, 264-268 (1990). Comparison of various diluent + modifier - silica systems for 57 solutes by graphical methods; i.e. RM vs. eluent spectra plotted on the basis of equieluotropic series of RM1 vs. RM2 correlations. The spread of points was largest when the binary eluents differed in both diluent and modifier. The differentiated selectivity characteristics of the diluent - modifier binaries demonstrate good prospects for computer-aided selection of an optimal system for TLC analysis of a given set of compounds from the data base.

Chromatographia 35, 275-280 (1993). Determination of the lipophilicity of 14 anti-hypoxia drugs by reverse-phase TLC on paraffin-impregnated silica with 25-60% acetonitrile in steps of 5% containing a changing or constant concentration of buffer. Detection under UV 254 nm. Discussion of the correlation between lipophilicity and the specific hydrophobic surface area of the drugs, and the effect of the concentration of buffer on the retention of the drugs. Comparison of the results with those obtained by reverse-phase HPLC.

Part 1. J. Planar Chromatogr. 9, 430-434 (1996). Investigation of the stability of RP-18 TLC stationary phases, specifically their resistance to cleavage of the chemical bonds coupling the octadecyl ligands to the silica matrix using methanol - phosphate buffer (pH 3) solutions, repeatedly passed through the layer. It was demonstrated that cleavage of about fifty percent of octadecyl ligands from the matrix occurs in the course of the initial two runs of the methanol - phosphate buffer solutions through the RP-18 layer, and after this the stationary phase remains stable.