J. Planar Chromatogr. 3, 425-528 (1990). It is proposed the RM values of substances analyzed on silica with tertiary mobile phases may be predicted from one-parameter regression equations. Experimental RM values for a group of isomers investigated have been compared with theoretical values calculated both on the basis of the author’s own studies (RMy = f(RMx)), and from Oscik’s theory. Substances chromatographed: o-, m- and p-isomers of aminophenol, ethylphenol, cresol, nitroaniline, nitrophenol, toluidine, chloroaniline, chlorophenol, nitrotoluene, chlorotoluene.

J. Planar Chromatogr. 6, 66-69 (1993). Use of a computer-assisted method to select the optimum mobile phase composition for the HPTLC separation of an unknown mixture of a pesticide intermediate. The method is based on spot order identification, by comparison of the UV spectra of spots, followed by single-factor optimization. Excellent agreement was obtained between predicted data and experimental results.

Chinese J. Chem. 14, 354-358 (1996). Presentation of a computer-assisted method for optimization of mobile phase composition and development distance in gradient two-step development HPTLC. The method is based on a system which can predict the final Rf values for gradient two-step development from values measured using five preliminary runs. The statistical scanning method is then used for optimization, using Rf difference as the selection criterion. The method was evaluated using a mixture of eight components and showed excellent agreement between predicted and experimental results.

J. Planar Chromatogr. 13, 337-347 (2000). HPTLC on cyano phases with five binary and ten ternary mobile phases containing methanol, acetonitrile, and water. A retention model was formulated at each composition using the solvation-parameter model. A mixture-design approach was then used to model the individual system constants as a continuous function of mobile phase composition, producing system surfaces from which retention surfaces could be calculated for method development. Regression analysis for the full data set indicated that the mixture-design models can be used to estimate solute migration properties with accuracy similar to that of the original solvation-parameter models.

Trends Anal. Chem. 81, 51-62 (2016). Review on aspects to consider during calibration for quantitative chromatographic analysis such as noise and detector response, data acquisition and processing, calibration curve and inverse calibration.

Determination of isoniazid in serum by thin-layer chromatography.) (Chinese). J. Pharm. Anal. (Yaowu Fenxi Zazhi) 17, 116-118 (1997). TLC on silica with chloroform - methanol 9:1. In situ spectra recording of isoniazid and its salicylaldehyde - and benzaldehyde-derivatives. Quantification by densitometry at 225 nm. Validation of the method by investigation of linearity and range, RSD, recovery and detection limits for the compounds.

J. of Chromatogr. B 879, 1764-1772 (2011). Quantitative structure-activity relationship (QSAR) analysis of 20 drugs with affinity for serotonin (5-HT) receptors by calculation of a set of physicochemical parameters and TLC data. TLC on silica gel and RP-2 impregnated with solutions of aspartic acid, serine, phenylalanine, tryptophan, tyrosine, asparagine, threonine and their mixtures, with two mobile phases - the systems were chosen as models of drug-5-HT-receptor interaction. The relationships between chromatographic data, molecular descriptors and biological activity data were found by regression analysis. The resulting correlations for the compounds with serotoninergic activity represent their interaction with the proposed biochromatographic models. The presented regression models based on biochromatographic studies can be an efficient tool in the QSAR analysis for initial prediction of compounds activity direction within 5-HT receptors.

J. Chromatogr. 262, 113-120 (1983). Separation performance data obtained under different conditions with a newly developed technique in the area of TLC, overpressured TLC (OPTLC). The changes in theoretical plate heights and resolution values for some lipophilic dyes were determined at different flow-rates, migration distances and layer thicknesses. Some of these data are compared with corresponding results obtained by linear high-performance TLC without pressure.