J. Planar Chromatogr. 8, 366 - 368 (1995). Study of the retention behavior of a series of para-substituted anilides on silica with nonaqueous mobile phases. The results were discussed in terms of the nature of the solute and the eluent. - TLC of N-substituted amides, N-substituted benzamides, and N-substituted a-phenylacetamides on silica with 8 different mobile phases; spots were observed under UV 254 nm.

J. Chromatogr. A 719, 45-51 (1996). Study of the relationship between the RM values obtained by TLC for phenols and connectivity indices. Presentation of the corresponding connectivity functions, selection based on their respective statistical parameters by using multivariate regression, and a correct prediction of the experimental elution sequence for the molecules using silica layers and mobile phases of different polarity. Random and stability studies of different prediction models.

J. Planar Chromatogr. 10, 406-410 (1997). To study the relationship between chemical structure and retention behavior in TLC on silica, the retention constants of variously substituted 1,2-O-isopropylidene derivatives of aldohexoses and 1,2-O-cyclohexylidene derivatives of aldopentoses were measured as a function of the composition of eight binary mobile phases. The slopes and intercepts of the linear relationships between the retention constant (RM) and the logarithm of the volume fraction of the polar mobile phase component were calculated and are discussed in relation to solute and mobile phase characteristics. The RF values and relative retention of compounds depend largely on the retention behavior of their substituents.

J. Chromatogr. A 847, 291-296 (1999). TLC of 16 neutral and cationic complexes containing from five-to seven-membered diamine chelate rings on thin layers of silica cellulose and polyacrylonitrile sorbents with six aqueous solution of ammonium sulfate at various concentrations. Establishment of hRf decreasing with increasing ring size in all of the instances, and Rm values being a linear function. Discussion also of the effect of salt concentration. Proposal of a mechanism based on hydrophobic interaction between the sorbend and sorbent.

Part 2. The lipophilicity of 1,6-diaryl-5,7(1H)dioxo-2,3-dihydroimidazo[1,2-a][1,3,5]triazines and 1-aryl-5,6(1H)dioxo-2,3-dihydroimidazo[1,2-a]imidazoles. J. Planar Chromatogr. 13, 130-134 (2000). Determination of the lipophilicity of twenty five new carbonyl derivatives of 1-aryl-2-aminoimidazolines-2 (twenty 1,6-diaryl-5,7(1H)dioxo-2,3-dihydroimidazo[1,2-a][1,3,5]triazines and five 1-aryl-5,6(1H)dioxo-2,3-dihydroimidazo[1,2-a]imidazoles) by RPTLC on commercial RP-18 silica gel plates with methanol - acetic acid - water. RM values for all the compounds were linearly dependent on mobile phase methanol concentration within the range of 60 to 90%.

II Dicarboxylic acids as the test analytes. J. Liq. Chrom. & Rel. Technol. 25, 1469-1482 (2002). Investigation of intermolecular hydrogen-bonding interactions among adsorbed analyte molecules (so-called lateral interactions), and their impact on the retention process. TLC of dicarboxylic acids (succinic acid, suberic acid and adipic acid) on cellulose with dioxane as mobile phase.

Chromatographia 62 (3-4), 121-126 (2005). 2,4-Dihydroxyphenylthioamide derivatives modified on the N-aryl ring have substantial fungicidal activity. To determine their quantitative structure-activity relationships their lipophilicity was determined by use of column liquid chromatography and thin-layer chromatography. Methanol - water systems were used as mobile phases and the linear dependences of retention (RM and log k) on volume fraction of organic modifier, phi, were determined. This enabled precise determination of lipophilicity (RMw and log kw) by extrapolation. Correlations were found between quantities characterizing the lipophilicity of the compounds. Deviations enabled discovery of compound structural features which increase or reduce lipophilicity. When these data were correlated with biological activity against the phytopathogenic fungi Alternaria alternata and Botrytis cinerea parabolic dependences were obtained.

J. Liq. Chromatogr. Relat. Technol. 33, 894-902 (2010). Five amphoteric piperazynyl fluoroquinolones and flumequine were analyzed in an RP system on C8 plates with acetonitrile/aqueous acidic mobile phases containing various concentrations of potassium perchlorate. Perchlorate as a so-called chaotropic ion caused the increase in the retention of basic fluoroquinolones. TLC of sarafloxacin, difloxacin, norfloxacin, enrofloxacin, ciprofloxacin, and flumequine on RP-8 with acetonitrile - water containing constant concentration of citric acid but various concentrations of potassium perchorate. After air-drying, fluoroquinolone zones were detected at 366 nm and 254 nm and flumequine only at 254 nm. The retention increased with the increasing concentrations of perchlorate ion in the mobile phase and achieved a plateau for the mobile phases containing 10-20 mM of chaotropic perchlorate.