Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      96 058
      Use of selected structural descriptors for evaluation of the lipophilicity of bile acids investigated by RP HPTLC
      Alina PYKA*, M. DOLOWY, D. GURAK (*Department of Analytical Chemistry, Faculty of Pharmacy, Silesian Academy of Medicine, Jagiellonska 4, 41-200 Sosnowiec, Poland)

      J. Planar Chromatogr. 18, 465-470 (2005). HPTLC of cholic, glycocholic, glycodeoxycholic, chenodeoxycholic, deoxycholic, lithocholic, and glycolithocholic acid on RP-18 W, RP-2, and cyano phases in a presaturated chamber with mixtures of an organic modifier (methanol, dioxane, acetonitrile, acetone) and water in different volume proportions which were varied in steps of 5 % from 35 to 80 %. Detection by spraying with a 10 % aqueous solution of sulfuric acid or by dipping in a 10 % solution of phosphomolybdic acid in ethanol and heating at 120 °C for 20 min. Investigation of relationships between lipophilicity obtained by use of RP-HPTLC, experimental and theoretical partition coefficients, and selected structural descriptors.

      Classification: 2d, 23b
      68 008
      Effect of the impregnating agent on the lipophilicity determination of some triazine and cyanophenyl derivatives
      Z. ILLES, T. CSERHATI*, (*Central Research Inst. for Chemistry, Hungarian Academy of Sciences, H-1525 Budapest, POB 17, Hungary)

      J. Planar Chromatogr. 3, 381-385 (1990). The retention of 13 2-nitro-4-cyanophenyl esters and 10 trisubstituted symmetric triazine derivatives was determined on silica layers impregnated with silicone oils of various molecular mass, and vinyl content. The data were evaluated by principal component (PC) analysis performed on the covariance and correlation matrices of the original data set. It was established that the retention of each solute increases with increasing vinyl content, and that the molecular mass has a lower impact on retention than does the vinyl content. Application of multivariate mathematical methods in the evaluation of RP retention data.

      Keywords:
      Classification: 2e
      70 007
      Retardation behavior and prediction of Rf values in TLC using the „PRISMA“ model
      P. HÄRMÄLÄ, (Pharmacognosy Div., Dept. of Pharm., Univ. of Helsinki, SF-001 70 Helsinki, Finland)

      I. Regular part of the model. J. Planar Chromatogr. 4, 460-466 (1991). Manual examination of the retardation behavior of 16 apolar, closely related coumarins in normal phase TLC using the regular part of the three-dimensional „PRISMA“ model. The results show a highly significant second order dependency between the retardation factor (Rt) and the solvent strength (vertical correlation), as well as between the retardation factor and the selectivity point (horizontal factor).

      Classification: 2e, 8b
      74 057
      Comparison of mobile phases and HPTLC qualitative and quantitative analysis, on preadsorbent silica gel plates, of phospholipids in Biomphalaria glabrata (gastropoda) infected with Echinostoma caproni (trematoda)
      M. K. PEREZ, B. FRIED, J. SHERMA*, (*Dept. of Chem., Lafayette College, Easton, PA 18042, USA)

      J. Planar Chromatogr. 7, 340-343 (1994). Comparative study of seven earlier reported (CBS 69 079) and six additional mobile phases for TLC of phospholipids. Best resolution and most sensitive detection of phospholipids was obtained by four unidimensional developments on silica with chloroform - methanol - isopropanol - 0.25 % potassium chloride - ethyl acetate 30:9:25:6:18. Visualization of amino lipids by spraying with 0.2 % ninhydrin in butanol saturated with water and of glycolipids by spraying with 0.5% a-naphthol in methanol - water 1:1, followed by drying, spraying with sulfuric acid - water 95:5 and heating at 100 °C. Quantification by densitometry at 400 nm.

      Classification: 2e, 11c
      82 007
      A new method for mobile phase optimization in high-performance thin-layer chromatography (HPTLC)
      C. CIMPOIU, L. JANTSCHI, T. HODISAN*, ('Babes-Bolyai' Univ., Fac. of Chem. and Chem. Eng.; 11 Arany Janos, 3400 Cluj-Napoca, Romania)

      J. Planar Chromatogr. 11, 191-194 (1998). Description of a new method used to optimize a ternary mobile phase used for separation of mixtures of organic compounds by HPTLC. Computer programs have been written to assist prediction of the optimum mobile phases. The method was found to be a rapid and efficient tool in mobile phase optimization. HPTLC of (chlordiazepoxide, oxazepam, nitrazepam, medazepam, diazepam) on silica gel with chloroform - acetone - i-propanol mixtures of different compositions. Densitometry at 254 nm.

      Keywords:
      Classification: 2e
      75 014
      Test procedure validation for the TLC assay of a degradation product in a pharmaceutical formulation
      S.W. SUN, H. FABRE*, H. MAILLOLS, (*Lab. de Chim. Anal., Fac. de Pharm., 34060 Montpellier, France)

      J. Liquid Chromatogr. 17, 2495-2509 (1994). Presentation of an experimental and statistical approach for validating the TLC assay of the title product, including the main particular aspects of the technique with a special focus on the detection and quantification limits. At the limit of quantification, in addition to the accuracy and repeatability tests, a ruggedness test has been investigated: the influence of the plate batch number, mobile phase composition and temperature on the assay results, resolution and Rf values.

      Classification: 2f, 32c
      94 002
      Validation of standardized high-performance thin-layer chromatographic methods for quality control and stability testing of herbals
      Kathrin KOLL*, E. REICH, Anne BLATTER, M. VEIT (*Forschungsvereinigung der Arzneimittel-Hersteller e. V. (FAH), Kranzweiherweg 10, 53489 Sinzig, Germany)

      J. AOAC Int. 86, 909-915 (2003). In quality control and stability testing of herbal medicinal products, fingerprint chomatograms are used as powerful tools to evaluate and compare the composition of compounds in such products. To fulfill the ICH- and GMP-based regulatory requirements in pharmaceutical QC, chromatographic fingerprint analysis needs to be validated. By considering the stationary phase, sample application, developing solvents, chromatogram development, plate labeling, derivatization, documentation, and chromatographic equipment the paper provides a comprehensive concept for evaluating validation parameters for planar chromatographic fingerprinting based on a standardized methodology. Validation parameters addressed include stability of the analyte, selectivity, robustness testing, and method reproducibility.

      Classification: 2f, 32e
      110 013
      Slantingly cross loading sample system enables simultaneous performance of separation and mixture to detect molecular interactions on thin-layer chromatography
      H. SHIMIZU-YUMOTO, N. HAYASHI*, K. ICHIMURA, M. NAKAYAMA (*Institute of Vegetable and Tea Science, National Agriculture and Food Research Organization, 2769 Kanaya-Shishidoi, Shimada, Shizuoka 428-8501, Japan)

      J. of Chromatogr. A 1245, 183-189 (2012). Anthocyanins are major flower pigments that can be affected by copigments, colorless compounds that can modify anthocyanin coloration. Application of TLC to separate and analyze anthocyanins and copigments. By slantingly cross loading samples compounds are symmetrically developed in various angles from the upper origin to individual Rf values and cross each other. Detection of copigments as color change on the developed line of anthocyanin. Demonstration by using pink sweet pea (Lathyrus odoratus L.) petals showing a more intense zone and a paler zone on the anthocyanin line. The zones were identified as kaempferol 3-rhamnoside and 2-cyanoethyl-isoxazolin-5-one. Kaempferol 3-rhamnoside is a flavonoid with general copigment effect of more intense and bluer coloration change, whereas the structure 2-cyanoethyl-isoxazolin-5-one is not a conventional copigment, it had a novel effect to change anthocyanin coloration paler while maintaining color tone.

      Classification: 2