Spot capacity in thin-layer chromatography. J. Chromatogr. 245, 1-20 (1982). The spot capacity in TLC is the number of spots resolved with a resolution of unity that can be placed between the sample spot and the spot of a non-retained compound. This is more difficult to calculate than the equivalent peak capacity in column chromatography. The spot capacity increases with decreasing diffusion coefficient and increasing kinetic coefficient of the solvent and plate quality. For a given solvent and development length there is an optimum particle size that provides the maximum spot capacity. The spot capacity also increases with increasing development distance towards a limit.

J. Chromatogr. 270, 97-194 (1983). The lipophilicity of some neutral, acidic and alkaline compounds was determined by reversed-phase thin-layer chromatography applying silica, aluminium oxide and cellulose in different degrees impregnated with paraffin oil as support. The lowest RM values were determined on cellulose support owing to its lower adsorptive capacity. The alkaline compounds showed higher RM values on silica and the acidic compounds on aluminium oxide, proving that also the surface pH value of the support influences the lipophilicity determination.

Chromatographia 18, 512-516 (1984). Test of the retention behaviour of some substituted benzoic acids on reversed-phase TLC plates in the presence of ammonium bromide and various tetraalkylammonium compounds with different alkyl chain lengths. Description of the dependence of the Rf values of the test materials on the alkyl chain length of the ion-pair reagent and on the type of the inorganic counter ion. Ion-pair TLC, theory.

J. Liquid Chromatogr. 14, 3061-3076 (1991). Study of the effect of the mobile phase on the retention of a set of structurally different solutes by using retention data estimated by HPTLC on silica, and by using activity coefficients in non-aqueous mobile phase determined on the basis of saturation solubility of solutes. Discussion of a common retention mechanism in liquid chromatography. The retention of solutes was affected by both mobile and stationary phase, and the magnitude of the effects depends on molecular structure of the solute.

Sz. Nyiredy, A. Kakuk (eds.): Planar Chromatography 2000, Lillafüred, Hungary, 24-26 June 2000, Res. Inst. for Med. Plants, p. 11-18. HPTLC of 45 aromatics with polar groups on RP18 and RP18 W with various binary solvent systems. One mobile phase component was water and the organic one was 70% methanol, 55% acetonitrile or 55% tetrahydrofuran. The smallest selectivity changes are observed between methanol and acetonitrile systems. Distinctive selectivity changes are caused by modifiers. Ternary solvent systems seem to be advantageous for fine tuning of the separation.

J. Planar Chromatogr. 26, 299-305 (2013). The review described the main reasons that transformed standard TLC into a reliable and regulatory acceptable technique. Different aspects that allowed the incorporation of quantitative TLC to the QA systems such as automation, standardization of analytical procedures and operational qualification and performance qualification, as well as development of digital technology and new instruments are discussed.

Examination of 150 known solvent systems. Demonstration by selecting the mobile phase for the separation of estigyn bromo derivatives

J. Chromatogr. 367, 155-159 (1986). Investigation of the utility of the reaction between alkylacrylates and diazomethane. TLC of whole homologous series of C1- C18 n-alkyl-3-alkoxy-carbonyl-2-pyrazolines on silica with binary systems containing benzene and ethyl acetate. Cellulose and octadecyl-bonded silica were also employed as sorbents.